| 1. |
- Törner, Anna, et al.
(author)
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Renal function in community-dwelling frail elderly : comparison between measured and predicted glomerular filtration rate in the elderly and proposal for a new cystatin C-based prediction equation
- 2008
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In: Aging Clinical and Experimental Research. - Milano : Editrice Kurtis. - 1594-0667 .- 1720-8319. ; 20:3, s. 216-225
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Journal article (peer-reviewed)abstract
- BACKGROUND AND AIMS: There is a great need to evaluate renal function regularly in elderly people. This study aimed at analyzing renal function in stable, community-dwelling elderly people of 75 years and over, to compare measured and predicted glomerular filtration rates (GFR) and to develop an accurate prediction equation for this age group. METHODS: Forty-five ambulatory elderly people in stable health in ordinary living were randomly selected into four age-classes, aged 75-95. Demographic data, personal activities of daily living, continuous drug prescriptions, body composition, blood pressure and blood chemistry were analysed. GFR was measured as Iohexol clearance based on three time-points 3, 4 and 7 hours after Iohexol injection. RESULTS: Mean GFR was well preserved in all four age-classes. The GFR range was 18-83 mL/min and declined with age. The Cockcroft-Gault prediction equation systematically underestimated measured GFR. A new 'GFRA' prediction equation is presented, based on the inverse of serum cystatin C and independent of gender, body surface area, body weight, lean body mass or serum creatinine. The proposed equation underestimated measured GFR with a mean of only 0.1 mL/min, had better precision compared with the Cockcroft-Gault equation, and was evaluated by the method of cross-validation. CONCLUSIONS: GFR exhibits extensive heterogeneity in frail, community-dwelling elderly people. The proposed GFRA was clearly more precise than the Cockcroft-Gault prediction equation in the study group. However, it needs to be validated in a larger population of elderly subjects, including more individuals in stable health with substantially reduced renal function in whom GFR is measured by a reference method with adequate sampling time.
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| 2. |
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| 3. |
- Rydwik, Elisabeth, et al.
(author)
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Effects of a physical and nutritional intervention program for frail elderly people over age 75 : a randomized controlled pilot treatment trial
- 2008
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In: Aging Clinical and Experimental Research. - Milano, Italy : Editrice Kurtis. - 1594-0667 .- 1720-8319. ; 20:2, s. 159-170
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Journal article (peer-reviewed)abstract
- BACKGROUND AND AIMS: There are few studies published that combine the interventions of physical training and nutrition. The aim of the present study was to describe the impact of a physical and nutritional intervention program for frail community- dwelling elderly people over the age of 75. METHODS: Ninety-six community-dwelling elderly people (58 women) were randomized to four different groups: i) a physical training program (aerobic, muscle strength, balance), ii) a nutritional intervention program (individually targeted advice and group sessions), iii) a combination of these interventions, and iv) a control group. At baseline subjects were screened for physical performance such as muscle strength, balance, mobility and activities of daily living, as well as nutritional aspects such as energy intake, body weight and fat-free mass. These measurements were repeated immediately after the intervention, which lasted for 12 weeks, and after another 6 months. RESULTS: The intention-to-treat analysis indicated significant improvements in lower- extremity muscle strength in both training groups compared with the nutrition group at 1st follow-up. There were small significant changes for some of the balance measurements in the training group without nutrition treatment. The nutrition intervention did not show any significant results. CONCLUSIONS: This study shows the positive effect on lower-extremity muscle strength directly after the intervention. Balance training most probably needs to be more individualized in order to be effective for frail elderly people. Further studies are needed, with larger sample sizes, to investigate the effects of these types of interventions before any further conclusions can be drawn.
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| 4. |
- Akner, Gunnar, 1953-, et al.
(author)
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Personalized Geriatric Medicine
- 2014
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In: European Geriatric Medicine. - : Elsevier BV. - 1878-7649 .- 1878-7657. ; 5, s. 145-146
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Journal article (peer-reviewed)
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| 5. |
- Akner, Gunnar, 1953-
(author)
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Geriatric care in Sweden
- 2014
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In: Current Diagnosis & Treatment. - USA : McGraw-Hill. - 9780071792080 ; , s. 539-542
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Book chapter (peer-reviewed)
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| 6. |
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| 7. |
- Akner, Gunnar, 1953-, et al.
(author)
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Multisjuka och bräckliga äldre
- 2015. - 1
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In: Mat och hälsa. - Stockholm : Studentlitteratur AB. - 9789144083575 ; , s. 105-108
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Book chapter (other academic/artistic)
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| 8. |
- Akner, Gunnar, 1953-
(author)
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Multisjuklighet hos äldre personer
- 2012. - 1
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In: Äldres hälsa. - Lund : Studentlitteratur AB. - 9789144073125 ; , s. 367-382
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Book chapter (other academic/artistic)
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| 9. |
- Akner, Gunnar, 1953-, et al.
(author)
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Vanligt att kommunalt bistånd till äldre rör nutrition
- 2013
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In: Läkartidningen. - 0023-7205 .- 1652-7518. ; 110:45
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Journal article (other academic/artistic)abstract
- För ungefär hälften av de personer över 65 år som hade kommunalt bistånd för vård och omsorginsatser var biståndsbesluten relaterade till mat, måltider eller nutrition. Det visar en punktprevalensstudie i Örebro kommun.
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