| 1. |
- Hanner, P, et al.
(författare)
-
Clinical observations of effects on central nervous system in patients with acute facial palsy.
- 1987
-
Ingår i: Archives of otolaryngology--head & neck surgery. - 0886-4470. ; 113:5, s. 516-20
-
Tidskriftsartikel (refereegranskat)abstract
- Twenty-eight consecutive patients with acute unilateral facial palsy were examined with special reference to clinical signs of central nervous system involvement. The clinical investigation in the acute stage of the disease showed that only seven patients had solitary facial nerve dysfunction, while the remaining patients had evidence of more widespread disease involvement. The most frequent finding was a trigeminal dysfunction of the paretic side, as shown by paresthesia and sensibility disturbance corresponding to the sensoritrigeminal area, as well as a dysfunction of the trigeminal component of the corneal reflex of the paretic side. Three patients showed migrating symptoms that were suggestive of a brain-stem disorder. In addition, four patients had an optic neuropathy, while an abnormal brain-stem audiometry response was demonstrated in five patients. The outcome of acute facial palsy one to two years after onset, however, could not be predicted from the clinical central nervous system signs. The degree of the palsy in the acute stage of the disease still seemed to be one of the most important prognostic factors. It is concluded that acute facial palsy is not a single entity, but rather a feature of different neurologic conditions.
|
|
| 2. |
- Frisén, Lars, 1939, et al.
(författare)
-
A primer of ophthalmic computer graphics.
- 1990
-
Ingår i: Documenta ophthalmologica. Advances in ophthalmology. - 0012-4486. ; 74:4, s. 337-50
-
Tidskriftsartikel (refereegranskat)abstract
- Computer graphics offers an unprecedented opportunity to probe new and old ideas in vision testing, without going to the expense of building dedicated equipment. However, the large variety of computer hardware is bewildering and only occasionally can commercial software tools be used. This mini review of the basic principles of computer graphics on personal computers is intended to help the newcomer to the field.
|
|
| 3. |
- Frisén, Lars, 1939, et al.
(författare)
-
A simple relationship between the probability distribution of visual acuity and the density of retinal output channels.
- 1976
-
Ingår i: Acta ophthalmologica. - 0001-639X. ; 54:4, s. 437-44
-
Tidskriftsartikel (refereegranskat)abstract
- Throughout the retina, the parameters of the probability distribution of visual acuity for monochromatic interference fringes are closely proportional to the number of retinal ganglion cells per degree of visual angle. There are no simple relationships to receptor spatial frequencies. These findings suggest that neuro-retinal acuity is determined principally by the spatial frequency of neural output channels.
|
|
| 4. |
|
|
| 5. |
- Frisén, Lars, 1939
(författare)
-
Acuity perimetry: estimation of neural channels.
- 1988
-
Ingår i: International ophthalmology. - 0165-5701. ; 12:3, s. 169-74
-
Tidskriftsartikel (refereegranskat)abstract
- Measurements of peripheral visual acuity allow quantitative estimations of retino-cortical neural channels. Analysis of results from high-pass resolution perimetry revealed that about 2/3 of all channels are contained within 30 degrees of visual field eccentricity and that loss of 1/3 raises the average threshold level about 1 decibel. The analytical procedure can be applied to any type of visual field defect.
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
- Frisén, Lars, 1939, et al.
(författare)
-
Binocular summation in humans: evidence for a hierarchic model.
- 1988
-
Ingår i: The Journal of physiology. - 0022-3751. ; 402, s. 773-82
-
Tidskriftsartikel (refereegranskat)abstract
- 1. Binocular summation was studied in human subjects using a batter of vision tests. Two tests assessed detection, another three acuity, one hyperacuity and one pattern recognition. 2. The magnitude of summation was consistent with, or exceeded, the level predicted from quadratic summation for both detection tests. 3. The summation factor was significantly smaller in the resolution tests than in the detection tests. Hyperacuity showed a large individual variation. 4. Spatial filtering of acuity targets did not influence summation. 5. No summation was found in the pattern recognition test. 6. It is argued that the degree of summation is related to the complexity of the visual task. A simple task yields a larger binocular summation than a more complex one. This may be related to the level of processing in the primary visual cortex.
|
|
| 9. |
- Frisén, Lars, 1939, et al.
(författare)
-
Characterization of vigabatrin-associated optic atrophy.
- 2003
-
Ingår i: Acta ophthalmologica Scandinavica. - : Wiley. - 1395-3907. ; 81:5, s. 466-73
-
Tidskriftsartikel (refereegranskat)abstract
- To report the discovery of a previously unknown form of optic atrophy associated with use of the anti-epileptic drug vigabatrin.We conducted a retrospective analysis of digitally enhanced ocular fundus photographs, kinetic visual field maps and treatment parameters for 25 patients, who were selected to represent a large spectrum of visual field defects.In all, 21 patients (84%) evidenced subtle, diffuse atrophy of the retinal nerve fibre layer, in a pattern accessible to scoring. Atrophy scores correlated with visual field remains and cumulative vigabatrin doses. A pathophysiological model is proposed that involves the lengths of intraocular (unmyelinated) retinal ganglion cell axons.Optic atrophy attests to the irreversible nature of vigabatrin's visual toxicity. Ocular fundus imaging should prove useful for objectively monitoring vigabatrin-treated subjects for visual toxicity.
|
|
| 10. |
|
|
