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Träfflista för sökning "AMNE:(MEDICIN OCH HÄLSOVETENSKAP Medicinska grundvetenskaper Farmakologi och toxikologi) ;mspu:(conferencepaper)"

Sökning: AMNE:(MEDICIN OCH HÄLSOVETENSKAP Medicinska grundvetenskaper Farmakologi och toxikologi) > Konferensbidrag

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Numrering	Referens	Omslagsbild	Hitta
1.	Munthe, Christian, 1962 (författare) Ethical aspects on prioritisation of new cancer drugs 2015 Ingår i: 11th Nordic Melanoma Meeting, Gothenburg, 3 September, 2015. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
2.	Winder, Michael, 1980 (författare) The ambiguous role of nitric oxide in the urinary bladder 2017 Ingår i: 7th National Symposium on Advances in Gastrointestinal & Urogenital Research, 2017, Gold Coast, Australia. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
3.	Helldén, Anders, et al. (författare) Aciclovir- a nearly atoxic antiviral drug with severe neurotoxic side effects. A retrospective review of 280 cases and the importance of analysing the aciclovir metabolite CMMG. 2008 Ingår i: 2nd World Conference on Magic Bullets (Ehrlich II) Nürnberg, Germany 2008. Konferensbidrag (refereegranskat)abstract Aciclovir- a nearly atoxic antiviral drug with severe neurotoxic side effects. A retrospective review of 280 cases and the importance of analysing the aciclovir metabolite CMMG.
4.	Östman, Elin, et al. (författare) Improvement of the metabolic features of bread by use of organic acids. 2003 Ingår i: Annals of Nutrition and Metabolism. - : S. Karger AG. - 0250-6807 .- 1421-9697. ; 47:6, s. 638-638, s. 106-106 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
5.	Bergström, Ulrika, et al. (författare) Neurotoxicity of the Olfactory toxicant 2,6-Dichlorophenyl Methylsulphone in Olfactory bulb:Impaired expression of genes relating to neurodegenerative disease 2007 Ingår i: DIOXIN2007. ; , s. 1841-1844 Konferensbidrag (refereegranskat)
6.	Rolfö, Linda, et al. (författare) Predictors of Preference for the Activity-based Flexible Office 2019 Ingår i: Human Systems Engineering and Design. - Cham : Springer. - 9783030020521 - 9783030020538 ; 876, s. 547-553 Konferensbidrag (refereegranskat)abstract Activity-based Flexible Offices (A-FOs) are implemented with varying degree of success. Employees relocate from cell or open-plan offices, from different organizational backgrounds, varying design and implementation processes, and have different types of work tasks. This study aims at investigating whether preference for the A-FO correlate with these preconditions. The results from Chi-square tests and Spearman’s non-parametric correlation of post-relocation questionnaires distributed to 11 A-FO sites, showed that a high preference for the A-FO correlated strongest with an A-FO preference prior to relocation, being a former open-plan office occupier and with frequent performance of innovation. Low preference for the A-FO correlated with frequent performance of concentration demanding tasks. Working with tasks with high confidentiality did not predict the preference ratings.
7.	Hedmer, Maria, et al. (författare) Cyklofosfamid (CP) i urin vid riskvärdering vid cytostatikaarbete 2003 Konferensbidrag (refereegranskat)
8.	Lundälv, Jörgen, 1966 (författare) Terroristen trenger journalisten. Bioterrorisme og media, trusselbilder og erfaringer fra konkrete cases 2006 Ingår i: Oral Presentation, Konferense Informasjonsberedskap 2006. Tema: Smitte og bioterrorisme. Konferens 7 september 2006 i Trondheim, Norge.. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
9.	Memedi, Mevludin, 1983-, et al. (författare) Upper limb motor tests are related to clinical ratings of motor function in advanced Parkinson's disease 2016 Ingår i: Movement Disorders. Vol. 31, suppl. 2, s. 640-641, nr. 1948. - : John Wiley & Sons. - 0885-3185 .- 1531-8257. Konferensbidrag (övrigt vetenskapligt/konstnärligt)
10.	Abbas, Abdul-Karim, 1959, et al. (författare) Pharmacological characteristics of protein synthesis inhibitors by radioactive leucine incorporation in rat hippocampal slices: experimental evidence and pre-clinical implications 2011 Ingår i: The 23rd Biennial Meeting of the International Society for Neurochemistry (ISN), August 28-September 1 2011, Athens, Greece. Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract Protein synthesis inhibitors (PSIs) constitute a major tool to validate the hypothesis of protein synthesis-dependent phase of synaptic plasticity and memory consolidation. However, several reports have showed inconsistent findings about the effect of these drugs on behavioral learning and synaptic plasticity. Testing the potencies of these drugs is hence crucial for validating such negative findings and in planning future studies. It is also necessary to examine the dose dependence, onset dynamics and reversibility, and possible effects on basal proteins. Here we used the labeled leucine as marker for the newly synthesized proteins. The fraction of leucine incorporation, following 50 min of pre-incubation, was compared between two groups of slices: a PSI-treated and a control group. Both anisomycin and cycloheximide revealed a dose-dependent but time-independent manner of inhibition reaching over 92% at concentrations well below those used in previous experiments which revealed effects on synaptic plasticity and learning. Surprisingly, washout of a “reversible” inhibitor, anisomycin was not followed by rapid reversibility of the action of the drug, the case that differs with cycloheximide. Interestingly, emetine revealed a time-dependent inhibition of protein synthesis, where levels above 80% needed drug pre-incubation for as long as 90 min. Since the duration of labeling relates to the half-life of the proteins, short-time labeling as used in this study will result in radioactivity incorporation into short-lived proteins and proteins that are synthesized in large quantities. We therefore studied the availability of newly synthesized proteins at 8-10 h following leucine incorporation. The results revealed virtually the same protein content as in slices retrieved for analysis immediately following the labeling period, indicating that the main pool of the newly synthesized proteins is of intracellular long-lived pool. This likely reflects a stable metabolic state of our prepared slices. These findings challenge current idea on the role of de novo protein synthesis in synaptic plasticity as well as brain changes underlying several neurological and psychiatric disorders.

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Typ av publikation: konferensbidrag (301)Ta bort avgränsningen

Typ av innehåll: övrigt vetenskapligt/konstnärligt (157); refereegranskat (144)

Författare/redaktör: Backhaus, Thomas, 19 ... (47); Aronsson, Patrik, 19 ... (40); Winder, Michael, 198 ... (33); Tobin, Gunnar, 1954 (25); Kempe, Maria (24); Carlsson, Thomas, 19 ... (21); visa fler...; Celander, Malin C., ... (14); Hedlund, Petter (11); Johnsson, Martin, 19 ... (11); Dave, Göran, 1945 (10); Decker, Ralph, 1968 (10); Blanck, Hans, 1950 (10); Albertsson-Wikland, ... (9); Kempe, Henrik (9); Andersson, Michael, ... (8); Stenqvist, Johanna (8); Wassmur, Britt, 1976 (8); Gräns, Johanna, 1979 (8); Ekström, Jörgen, 194 ... (7); Andersson, K E (7); Giglio, Daniel, 1977 (7); Dahlgren, Jovanna, 1 ... (7); Kriström, Berit, 194 ... (7); Grubb, Anders (6); Höglund, Peter (6); Jirstrand, Mats, 196 ... (6); Hasselberg, Linda, 1 ... (6); Söderpalm, Bo, 1959 (5); Ericson, Mia, 1970 (5); Meyer, W. (5); Gabrielsson, Johan (5); Lithner, Delilah, 19 ... (5); Oskarsson, Agneta (5); Frische, Tobias (5); Eriksson, Martin, 19 ... (5); Chau, Pei Pei, 1981 (5); Gratzke, C (5); Matzke, M. (5); Stief, C. G. (5); Hassold, Enken (5); Bergquist, Filip, 19 ... (4); Lundqvist, Johan (4); Larsson, Åke, 1944 (4); Aydogdu, Özgu, 1978 (4); Pålsson, Erik, 1975 (4); Klamer, Daniel, 1976 (4); Grimme, L H (4); Svensson, Lennart, 1 ... (4); Fejgin, Kim, 1978 (4); Weinhold, P. (4); visa färre...

Lärosäte: Göteborgs universitet (180); Lunds universitet (72); Chalmers tekniska högskola (22); Sveriges Lantbruksuniversitet (14); Umeå universitet (7); Uppsala universitet (6); visa fler...; Linnéuniversitetet (5); Stockholms universitet (4); Karolinska Institutet (4); Malmö universitet (3); Kungliga Tekniska Högskolan (2); Linköpings universitet (2); Högskolan i Gävle (1); Örebro universitet (1); RISE (1); Karlstads universitet (1); visa färre...

Språk: Engelska (296); Svenska (4); Tyska (1)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (301); Naturvetenskap (96); Samhällsvetenskap (7); Teknik (6); Lantbruksvetenskap (6); Humaniora (1)

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