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Träfflista för sökning "AMNE:(MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Farmaceutiska vetenskaper) ;mspu:(patent)"

Search: AMNE:(MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Farmaceutiska vetenskaper) > Patent

  • Result 1-4 of 4
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1.
  • Eriksson, Leif A., 1964-, et al. (author)
  • Tetrazole derivatives as cytochrome p450 inhibitors
  • 2019
  • Patent (pop. science, debate, etc.)abstract
    • According to the invention there is provided a compound of formula I, wherein R1 and R2 have meanings given in the description, which compounds are useful in the treatment of skin disorders and other diseases.
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2.
  • Andersson, Sören, 1957-, et al. (author)
  • CHIMERIC MOMP ANTIGEN
  • 2015
  • Patent (pop. science, debate, etc.)
  •  
3.
  • Ragno, Rino, et al. (author)
  • Structure-based modeling and target-selectivity prediction
  • 2014
  • Patent (pop. science, debate, etc.)abstract
    • The present invention provides, inter alia, methods, models, and systems for selecting an effector having specificity for a target molecule. The methods and systems of the present invention involve several steps, including compiling a database containing structural data for a library of molecules and a population of ligands and activity data, establishing structure-based equivalence of sequence elements in the library of molecules, determining likely spatial orientations of population ligands in library molecules, calculating interaction energies for each ligand-molecule pair, generating statistical models that are predictive of sequence elements likely to contribute to a differential effect of ligands on molecules, selecting an effector that is likely to have a desired specificity for the target molecule, experimentally determining activity data for effector-library molecule pairs, and at least once repeating the steps listed above wherein the effector is a member of the population of ligands.
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  • Result 1-4 of 4

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