| 1. |
- Sanli, Kemal, et al.
(författare)
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Metagenomic Sequencing of Marine Periphyton: Taxonomic and Functional Insights into Biofilm Communities
- 2015
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Ingår i: Frontiers in Microbiology. - : Frontiers Media SA. - 1664-302X. ; 6:1192
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Tidskriftsartikel (refereegranskat)abstract
- Periphyton communities are complex phototrophic, multispecies biofilms that develop on surfaces in aquatic environments. These communities harbor a large diversity of organisms comprising viruses, bacteria, algae, fungi, protozoans and metazoans. However, thus far the total biodiversity of periphyton has not been described. In this study, we use metagenomics to characterize periphyton communities from the marine environment of the Swedish west coast. Although we found approximately ten times more eukaryotic rRNA marker gene sequences compared to prokaryotic, the whole metagenome-based similarity searches showed that bacteria constitute the most abundant phyla in these biofilms. We show that marine periphyton encompass a range of heterotrophic and phototrophic organisms. Heterotrophic bacteria, including the majority of proteobacterial clades and Bacteroidetes, and eukaryotic macro-invertebrates were found to dominate periphyton. The phototrophic groups comprise Cyanobacteria and the alpha-proteobacterial genus Roseobacter, followed by different micro- and macro-algae. We also assess the metabolic pathways that predispose these communities to an attached lifestyle. Functional indicators of the biofilm form of life in periphyton involve genes coding for enzymes that catalyze the production and degradation of extracellular polymeric substances, mainly in the form of complex sugars such as starch and glycogen-like meshes together with chitin. Genes for 278 different transporter proteins were detected in the metagenome, constituting the most abundant protein complexes. Finally, genes encoding enzymes that participate in anaerobic pathways, such as denitrification and methanogenesis, were detected suggesting the presence of anaerobic or low-oxygen micro-zones within the biofilms.
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| 2. |
- Dodig-Crnkovic, Gordana, 1955
(författare)
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Cognitive Architectures Based on Natural Info-Computation
- 2022
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Ingår i: Studies in Applied Philosophy, Epistemology and Rational Ethics. - Cham : Springer. - 2192-6255 .- 2192-6263. ; , s. 3-13, s. 3-13
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Bokkapitel (refereegranskat)abstract
- At the time when the first models of cognitive architectures have been proposed, some forty years ago, understanding of cognition, embodiment and evolution was substantially different from today’s. So was the state of the art of information physics, information chemistry, bioinformatics, neuroinformatics, computational neuroscience, complexity theory, self-organization, theory of evolution, as well as the basic concepts of information and computation. Novel developments support a constructive interdisciplinary framework for cognitive architectures based on natural morphological computing, where interactions between constituents at different levels of organization of matter-energy and their corresponding time-dependent dynamics, lead to complexification of agency and increased cognitive capacities of living organisms that unfold through evolution. Proposed info-computational framework for naturalizing cognition considers present updates (generalizations) of the concepts of information, computation, cognition, and evolution in order to attain an alignment with the current state of the art in corresponding research fields. Some important open questions are suggested for future research with implications for further development of cognitive and intelligent technologies.
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| 3. |
- Liu, Yuanhua, 1971, et al.
(författare)
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Considering the importance of user profiles in interface design
- 2009
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Ingår i: User Interfaces. ; , s. 23-
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- User profile is a popular term widely employed during product design processes by industrial companies. Such a profile is normally intended to represent real users of a product. The ultimate purpose of a user profile is actually to help designers to recognize or learn about the real user by presenting them with a description of a real user’s attributes, for instance; the user’s gender, age, educational level, attitude, technical needs and skill level. The aim of this chapter is to provide information on the current knowledge and research about user profile issues, as well as to emphasize the importance of considering these issues in interface design. In this chapter, we mainly focus on how users’ difference in expertise affects their performance or activity in various interaction contexts. Considering the complex interaction situations in practice, novice and expert users’ interactions with medical user interfaces of different technical complexity will be analyzed as examples: one focuses on novice and expert users’ difference when interacting with simple medical interfaces, and the other focuses on differences when interacting with complex medical interfaces. Four issues will be analyzed and discussed: (1) how novice and expert users differ in terms of performance during the interaction; (2) how novice and expert users differ in the perspective of cognitive mental models during the interaction; (3) how novice and expert users should be defined in practice; and (4) what are the main differences between novice and expert users’ implications for interface design. Besides describing the effect of users’ expertise difference during the interface design process, we will also pinpoint some potential problems for the research on interface design, as well as some future challenges that academic researchers and industrial engineers should face in practice.
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| 4. |
- Abarenkov, Kessy, et al.
(författare)
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Annotating public fungal ITS sequences from the built environment according to the MIxS-Built Environment standard – a report from a May 23-24, 2016 workshop (Gothenburg, Sweden)
- 2016
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Ingår i: MycoKeys. - : Pensoft Publishers. - 1314-4057 .- 1314-4049. ; 16, s. 1-15
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Tidskriftsartikel (refereegranskat)abstract
- Recent molecular studies have identified substantial fungal diversity in indoor environments. Fungi and fungal particles have been linked to a range of potentially unwanted effects in the built environment, including asthma, decay of building materials, and food spoilage. The study of the built mycobiome is hampered by a number of constraints, one of which is the poor state of the metadata annotation of fungal DNA sequences from the built environment in public databases. In order to enable precise interrogation of such data – for example, “retrieve all fungal sequences recovered from bathrooms” – a workshop was organized at the University of Gothenburg (May 23-24, 2016) to annotate public fungal barcode (ITS) sequences according to the MIxS-Built Environment annotation standard (http://gensc.org/mixs/). The 36 participants assembled a total of 45,488 data points from the published literature, including the addition of 8,430 instances of countries of collection from a total of 83 countries, 5,801 instances of building types, and 3,876 instances of surface-air contaminants. The results were implemented in the UNITE database for molecular identification of fungi (http://unite.ut.ee) and were shared with other online resources. Data obtained from human/animal pathogenic fungi will furthermore be verified on culture based metadata for subsequent inclusion in the ISHAM-ITS database (http://its.mycologylab.org).
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| 5. |
- Dodig-Crnkovic, Gordana, 1955
(författare)
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Natural Morphological Computation as Foundation of Learning to Learn in Humans, Other Living Organisms, and Intelligent Machines
- 2020
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Ingår i: Philosophies. - Basel, Switzerland : MDPI AG. - 2409-9287. ; 5:3
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Tidskriftsartikel (refereegranskat)abstract
- The emerging contemporary natural philosophy provides a common ground for the integrative view of the natural, the artificial, and the human-social knowledge and practices. Learning process is central for acquiring, maintaining, and managing knowledge, both theoretical and practical. This paper explores the relationships between the present advances in understanding of learning in the sciences of the artificial (deep learning, robotics), natural sciences (neuroscience, cognitive science, biology), and philosophy (philosophy of computing, philosophy of mind, natural philosophy). The question is, what at this stage of the development the inspiration from nature, specifically its computational models such as info-computation through morphological computing, can contribute to machine learning and artificial intelligence, and how much on the other hand models and experiments in machine learning and robotics can motivate, justify, and inform research in computational cognitive science, neurosciences, and computing nature. We propose that one contribution can be understanding of the mechanisms of 'learning to learn', as a step towards deep learning with symbolic layer of computation/information processing in a framework linking connectionism with symbolism. As all natural systems possessing intelligence are cognitive systems, we describe the evolutionary arguments for the necessity of learning to learn for a system to reach human-level intelligence through evolution and development. The paper thus presents a contribution to the epistemology of the contemporary philosophy of nature.
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| 6. |
- Chatterjee, Bapi, 1982
(författare)
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Lock-free Concurrent Search
- 2017
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The contemporary computers typically consist of multiple computing cores with high compute power. Such computers make excellent concurrent asynchronous shared memory system. On the other hand, though many celebrated books on data structure and algorithm provide a comprehensive study of sequential search data structures, unfortunately, we do not have such a luxury if concurrency comes in the setting. The present dissertation aims to address this paucity. We describe novel lock-free algorithms for concurrent data structures that target a variety of search problems. (i) Point search (membership query, predecessor query, nearest neighbour query) for 1-dimensional data: Lock-free linked-list; lock-free internal and external binary search trees (BST). (ii) Range search for 1-dimensional data: A range search method for lock-free ordered set data structures - linked-list, skip-list and BST. (iii) Point search for multi-dimensional data: Lock-free kD-tree, specially, a generic method for nearest neighbour search. We prove that the presented algorithms are linearizable i.e. the concurrent data structure operations intuitively display their sequential behaviour to an observer of the concurrent system. The lock-freedom in the introduced algorithms guarantee overall progress in an asynchronous shared memory system. We present the amortized analysis of lock-free data structures to show their efficiency. Moreover, we provide sample implementations of the algorithms and test them over extensive micro-benchmarks. Our experiments demonstrate that the implementations are scalable and perform well when compared to related existing alternative implementations on common multi-core computers. Our focus is on propounding the generic methodologies for efficient lock-free concurrent search. In this direction, we present the notion of help-optimality, which captures the optimization of amortized step complexity of the operations. In addition to that, we explore the language-portable design of lock-free data structures that aims to simplify an implementation from programmer’s point of view. Finally, our techniques to implement lock-free linearizable range search and nearest neighbour search are independent of the underlying data structures and thus are adaptive to similar data structures.
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| 7. |
- David, I., et al.
(författare)
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Blended modeling in commercial and open-source model-driven software engineering tools: A systematic study
- 2023
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Ingår i: Software and Systems Modeling. - : Springer Science and Business Media LLC. - 1619-1366 .- 1619-1374. ; 22, s. 415-447
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Tidskriftsartikel (refereegranskat)abstract
- Blended modeling aims to improve the user experience of modeling activities by prioritizing the seamless interaction with models through multiple notations over the consistency of the models. Inconsistency tolerance, thus, becomes an important aspect in such settings. To understand the potential of current commercial and open-source modeling tools to support blended modeling, we have designed and carried out a systematic study. We identify challenges and opportunities in the tooling aspect of blended modeling. Specifically, we investigate the user-facing and implementation-related characteristics of existing modeling tools that already support multiple types of notations and map their support for other blended aspects, such as inconsistency tolerance, and elevated user experience. For the sake of completeness, we have conducted a multivocal study, encompassing an academic review, and grey literature review. We have reviewed nearly 5000 academic papers and nearly 1500 entries of grey literature. We have identified 133 candidate tools, and eventually selected 26 of them to represent the current spectrum of modeling tools.
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| 8. |
- Yun, Yixiao, 1987, et al.
(författare)
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Maximum-Likelihood Object Tracking from Multi-View Video by Combining Homography and Epipolar Constraints
- 2012
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Ingår i: 6th ACM/IEEE Int'l Conf on Distributed Smart Cameras (ICDSC 12), Oct 30 - Nov.2, 2012, Hong Kong. - 9781450317726 ; , s. 6 pages-
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Konferensbidrag (refereegranskat)abstract
- This paper addresses problem of object tracking in occlusion scenarios, where multiple uncalibrated cameras with overlapping fields of view are used. We propose a novel method where tracking is first done independently for each view and then tracking results are mapped between each pair of views to improve the tracking in individual views, under the assumptions that objects are not occluded in all views and move uprightly on a planar ground which may induce a homography relation between each pair of views. The tracking results are mapped by jointly exploiting the geometric constraints of homography, epipolar and vertical vanishing point. Main contributions of this paper include: (a) formulate a reference model of multi-view object appearance using region covariance for each view; (b) define a likelihood measure based on geodesics on a Riemannian manifold that is consistent with the destination view by mapping both the estimated positions and appearances of tracked object from other views; (c) locate object in each individual view based on maximum likelihood criterion from multi-view estimations of object position. Experiments have been conducted on videos from multiple uncalibrated cameras, where targets experience long-term partial or full occlusions. Comparison with two existing methods and performance evaluations are also made. Test results have shown effectiveness of the proposed method in terms of robustness against tracking drifts caused by occlusions.
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| 9. |
- Bengtsson-Palme, Johan, 1985, et al.
(författare)
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Improved software detection and extraction of ITS1 and ITS2 from ribosomal ITS sequences of fungi and other eukaryotes for analysis of environmental sequencing data
- 2013
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Ingår i: Methods in Ecology and Evolution. - 2041-210X. ; 4:10, s. 914-919
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Tidskriftsartikel (refereegranskat)abstract
- The nuclear ribosomal internal transcribed spacer (ITS) region is the primary choice for molecular identification of fungi. Its two highly variable spacers (ITS1 and ITS2) are usually species specific, whereas the intercalary 5.8S gene is highly conserved. For sequence clustering and blast searches, it is often advantageous to rely on either one of the variable spacers but not the conserved 5.8S gene. To identify and extract ITS1 and ITS2 from large taxonomic and environmental data sets is, however, often difficult, and many ITS sequences are incorrectly delimited in the public sequence databases. We introduce ITSx, a Perl-based software tool to extract ITS1, 5.8S and ITS2 – as well as full-length ITS sequences – from both Sanger and high-throughput sequencing data sets. ITSx uses hidden Markov models computed from large alignments of a total of 20 groups of eukaryotes, including fungi, metazoans and plants, and the sequence extraction is based on the predicted positions of the ribosomal genes in the sequences. ITSx has a very high proportion of true-positive extractions and a low proportion of false-positive extractions. Additionally, process parallelization permits expedient analyses of very large data sets, such as a one million sequence amplicon pyrosequencing data set. ITSx is rich in features and written to be easily incorporated into automated sequence analysis pipelines. ITSx paves the way for more sensitive blast searches and sequence clustering operations for the ITS region in eukaryotes. The software also permits elimination of non-ITS sequences from any data set. This is particularly useful for amplicon-based next-generation sequencing data sets, where insidious non-target sequences are often found among the target sequences. Such non-target sequences are difficult to find by other means and would contribute noise to diversity estimates if left in the data set.
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| 10. |
- Ge, Chenjie, 1991, et al.
(författare)
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Co-Saliency-Enhanced Deep Recurrent Convolutional Networks for Human Fall Detection in E-Healthcare
- 2018
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Ingår i: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. - 1557-170X. ; 2018-July, s. 1572-1575
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Konferensbidrag (refereegranskat)abstract
- This paper addresses the issue of fall detection from videos for e-healthcare and assisted-living. Instead of using conventional hand-crafted features from videos, we propose a fall detection scheme based on co-saliency-enhanced recurrent convolutional network (RCN) architecture for fall detection from videos. In the proposed scheme, a deep learning method RCN is realized by a set of Convolutional Neural Networks (CNNs) in segment-levels followed by a Recurrent Neural Network (RNN), Long Short-Term Memory (LSTM), to handle the time-dependent video frames. The co-saliency-based method enhances salient human activity regions hence further improves the deep learning performance. The main contributions of the paper include: (a) propose a recurrent convolutional network (RCN) architecture that is dedicated to the tasks of human fall detection in videos; (b) integrate a co-saliency enhancement to the deep learning scheme for further improving the deep learning performance; (c) extensive empirical tests for performance analysis and evaluation under different network settings and data partitioning. Experiments using the proposed scheme were conducted on an open dataset containing multicamera videos from different view angles, results have shown very good performance (test accuracy 98.96%). Comparisons with two existing methods have provided further support to the proposed scheme.
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