| 1. |
- Amundin, Mats, et al.
(författare)
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A proposal to use distributional models to analyse dolphin vocalisation
- 2017
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Ingår i: Proceedings of the 1st International Workshop on Vocal Interactivity in-and-between Humans, Animals and Robots, VIHAR 2017. - 9782956202905 ; , s. 31-32
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Konferensbidrag (refereegranskat)abstract
- This paper gives a brief introduction to the starting points of an experimental project to study dolphin communicative behaviour using distributional semantics, with methods implemented for the large scale study of human language.
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| 2. |
- Schötz, Susanne, et al.
(författare)
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Phonetic Characteristics of Domestic Cat Vocalisations
- 2017
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Ingår i: Proceedings of the 1st International Workshop on Vocal Interactivity in-and-between Humans, Animals and Robots, VIHAR 2017. - 9782956202905 ; , s. 5-6
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Konferensbidrag (refereegranskat)abstract
- The cat (Felis catus, Linneaus 1758) has lived around or with humans for at least 10,000 years, and is now one of the most popular pets of the world with more than 600 millionindividuals. Domestic cats have developed a more extensive, variable and complex vocal repertoire than most other members of the Carnivora, which may be explained by their social organisation, their nocturnal activity and the long period of association between mother and young. Still, we know surprisingly little about the phonetic characteristics of these sounds, and about the interaction between cats and humans.Members of the research project Melody in human–cat communication (Meowsic) investigate the prosodic characteristics of cat vocalisations as well as the communication between human and cat. The first step includes a categorisation of cat vocalisations. In the next step it will be investigated how humans perceive the vocal signals of domestic cats. This paper presents an outline of the project which has only recently started.
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| 3. |
- Keshavarz, Mahmoud, et al.
(författare)
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Orientations of Europe : Boats, the Mediterranean Sea and the Materialities of Contemporary Mobility Regimes
- 2018
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Ingår i: Borderlands e-journal. - Sydney, NSW, Australia : Borderlands. - 1447-0810. ; 17:2, s. 1-27
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Tidskriftsartikel (refereegranskat)abstract
- This paper is an investigation of how the specific design and materiality of the artefact of the boat, as well as the various material, visual, technical and geographical practices at work in the space of Mediterranean Sea, orientate a specific space and produce a selective politics of seeing, saving and framing of bodies on the move. It highlights how the very presence and movement of ‘unseaworthy boats’ in this actively orientated space of the sea brings to the fore the many strategies and techniques that have been employed to make it a space of European control. We argue that this is an active and deadly orientation carried out in an often dispersed number of practices and interventions within a seemingly flat space of water. The paper concludes that border transgressors’ act of moving by boat, with all of the losses involved, both challenge and potentially reorientate European mobility regimes.
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| 4. |
- Ribeiro, Luis, et al.
(författare)
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Industrial Agents for the Fast Deployment of Evolvable Assembly Systems
- 2015. - 1st ed.
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Ingår i: Industrial Agents. - Amsterdam, Netherlands : Elsevier. - 9780128003411 ; , s. 301-321, s. 301-322
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Bokkapitel (refereegranskat)abstract
- The current manufacturing scenario is characterized by high market unpredictability. Agility is therefore a central challenge for modern companies that need to understand and be proactive towards their product offer in respect to “what is offered, when it is offered, where, how and by whom” (Brown & Bessant 2003).The “what” and the “when” are particularly relevant to the research in emerging paradigms as they account for variety, customization and volume; and timing, speed and seasonality (Brown & Bessant 2003).In this scenario, several design approaches and models have been proposed in the last decade to enable re-configurability and subsequently enhance the companies’ ability to adjust their offer in nature and time.From a paradigmatic point of view research has concentrated on the organizational structure of the shop-floor and the associated controls aspects. Concepts like Reconfigurable Manufacturing Systems (RMS) (Koren & Shpitalni 2010) and Fractal Factories (FF) (Montreuil 1999) support the physical construction of production systems by regulating their layout and making a few assumptions on their logical organization. On the other hand, concepts like Bionic Manufacturing Systems (BMS)(Ueda 1992), Holonic Manufacturing Systems (HMS)(Van Brussel et al. 1998), Evolvable Assembly Systems (Ribeiro et al. 2010) essentially provide the theoretical guidelines for the logical/computational organization of the system (see (Tharumarajah 1996) for a comparison between BMS, HMS and FF and (Setchi & Lagos 2004) for the rationale supporting the shift from Dedicated Lines to Flexible Manufacturing System and finally RMS).While these paradigms provide the conceptual framework and the main design guidelines their actual interpretation and implementation has led to a wider set of architectures (Monostori, Váncza & Kumara 2006; Leitão 2009; Parunak 2000; Pěchouček & Mařík 2008).These architectures align the high-level principles with the technological offer and limitations while seeking to address the re-configurability requirements of (Mehrabi, Ulsoy & Koren 2000; Rösiö & Säfsten 2013):module mobility – modules are easy and quick to move and install;“diagnosability” – it is quick to identify the sources of quality and reliability problems;“integrability” – modules are easy to integrate into the rest of the system.“convertibility” – it is easy and quick to switch between existing products and it is easy to adapt the system to future products;scalability – it is easy to enlarge and downsize the production system;“automatibility” – a dynamic level of automation is enabled;modularity – all system elements are designed to be modular;customization – the capability and flexibility of the production system is designed according to the products to be produced in the system.Instant deployment, as addressed in the present chapter directly addresses mobility, “integrability”, “convertibility”, scalability and customization. Mechatronic modularity is a prerequisite and is enforced by the proposed architecture and the considered modular design. “Diagnosability” was not specifically tackled.In this context, the chapter analyses the agent-based architecture related with the Instantly Deployable Evolvable Assembly System (IDEAS) project that is inspired by the Evolvable Assembly System (EAS) paradigm (Ribeiro et al. 2010) as a mechanism to enable fast deployment of mechatronic modules. EAS advocates the use of process-oriented modules and envisions the production system as a collection of processes and the associated interacting agents.The architecture and the related test cases are used to draw the main lessons learned in respect to technological and conceptual implications.In this context, the remainder of this text is organized as follows: section 1.1 discusses the main deployment challenges, section 1.2 details the reference architecture and associated concepts, section 1.3 presents the principal implementation decisions, section 1.4 features the main lessons learned, sections 1.5 discusses the benefits of the proposed approach and finally section 1.6 reflects on the main conclusions.
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| 5. |
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| 6. |
- Zhang, Chi, et al.
(författare)
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Spatial-Temporal-Spectral LSTM: A Transferable Model for Pedestrian Trajectory Prediction
- 2023
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Ingår i: IEEE Transactions on Intelligent Vehicles. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2379-8858 .- 2379-8904.
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Tidskriftsartikel (refereegranskat)abstract
- Predicting the trajectories of pedestrians is critical for developing safe advanced driver assistance systems and autonomous driving systems. Most existing models for pedestrian trajectory prediction focused on a single dataset without considering the transferability to other previously unseen datasets. This leads to poor performance on new unseen datasets and hinders leveraging off-the-shelf labeled datasets and models. In this paper, we propose a transferable model, namely the “Spatial-Temporal-Spectral (STS) LSTM” model, that represents the motion pattern of pedestrians with spatial, temporal, and spectral domain information. Quantitative results and visualizations indicate that our proposed spatial-temporal-spectral representation enables the model to learn generic motion patterns and improves the performance on both source and target datasets. We reveal the transferability of three commonly used network structures, including long short-term memory networks (LSTMs), convolutional neural networks (CNNs), and Transformers, and employ the LSTM structure with negative log-likelihood loss in our model since it has the best transferability. The proposed STS LSTM model demonstrates good prediction accuracy when transferring to target datasets without any prior knowledge, and has a faster inference speed compared to the state-of-the-art models. Our work addresses the gap in learning knowledge from source datasets and transferring it to target datasets in the field of pedestrian trajectory prediction, and enables the reuse of publicly available off-the-shelf datasets.
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| 7. |
- Steins, Krisjanis
(författare)
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Towards Increased Use of Discrete-Event Simulation for Hospital Resource Planning
- 2017
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Health care systems in many countries are experiencing a growing demand while their resources remain limited. The discrepancy between demand and capacity creates many problems – long waiting times for treatment, overcrowding in hospital wards, high workload, etc. More efficient delivery of health care services can be achieved by better planning of its resources so that the mismatch between demand and capacity is minimized. Planning health care resources, including hospital resources, is difficult due to system complexity and variability in both resource availability and demand. Discrete-event simulation and other operational research methods can be used for solving planning problems in health care, and have been gaining increased attention from researchers during recent decades. Despite the growing number of academic publications, simulation appears to be less used in health care than in other application areas and only a small proportion of simulation studies is actually implemented.The aim of this thesis is to contribute to increased use of discrete-event simulation in hospital resource planning. The separate studies regarding intensive care unit capacity planning, operating room allocation strategies and the management of emergency patient flow in a radiology department highlight both the possibilities and the requirements for practical application of discrete-event simulation in hospital resource planning. The studies are described in five papers.In the first paper, the relationship between intensive care unit (ICU) occupancy and patient outcomes was investigated and the results showed that risk adjusted mortality was higher in the group of patients who were treated during high levels of occupancy. This indicates that appropriate planning of ICU resources is necessary to avoid adverse effects on patient outcomes.In the second paper, analysis of a relatively simple care chain consisting of two hospital departments – emergency and radiology – revealed a process that was not very well defined and measured. Investigation into data availability uncovered disparate information systems storing incompatible and fragmented data. It suggests that the current degree of process orientation and the current IT infrastructure does not enable efficient use of quantitative process analysis and management tools such as simulation.In the third paper, the value and possibilities of using simulation modelling in hospital resource planning were examined through the development and use of a simulation model for improved operating room time allocation and patient flow in a hospital operating department. The model was initially used for studying overcrowding in a post-anaesthesia care unit. Advanced planning logic implemented in the model enabled evaluation of several different scenarios aiming to improve the utilization of operating room resources. The results showed that it is possible to achieve slightly better and more even resource utilization, as well as provide greater flexibility in scheduling operations.In the fourth paper, a generic ICU model was developed and validated using data from four different hospital ICUs. The model was adapted and calibrated stepwise in order to identify important parameters and their values to obtain a match between model predictions and actual data. The study showed that in presence of high quality data and well defined process logic it is possible to develop a generic ICU simulation model that could provide accurate decision support for planning critical care resources.In the fifth paper, a number of factors that can contribute to successful implementation of simulation results in health care were identified. The timing of the simulation study must be right to support a critical decision, the benefit from implementation should clearly outweigh the cost of making the necessary changes and the model should be thoroughly validated to increase the credibility of the results. Staff involvement in simulation modelling activities, availability of good quality data, as well as proper incentives to improve the system contribute to implementation as well. These findings can help in establishing the conditions for successful implementation in future applications of simulation modelling in health care.
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| 8. |
- Brännmark, Cecilia, et al.
(författare)
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Mathematical modeling of white adipocyte exocytosis predicts adiponectin secretion and quantifies the rates of vesicle exo- and endocytosis
- 2017
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Ingår i: Journal of Biological Chemistry. - : AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. - 0021-9258 .- 1083-351X. ; 292:49, s. 20032-20043
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Tidskriftsartikel (refereegranskat)abstract
- Adiponectin is a hormone secreted from white adipocytes and takes part in the regulation of several metabolic processes. Although the pathophysiological importance of adiponectin has been thoroughly investigated, the mechanisms controlling its release are only partly understood. We have recently shown that adiponectin is secreted via regulated exocytosis of adiponectin-containing vesicles, that adiponectin exocytosis is stimulated by cAMP-dependent mechanisms, and that Ca2+ and ATP augment the cAMP-triggered secretion. However, much remains to be discovered regarding the molecular and cellular regulation of adiponectin release. Here, we have used mathematical modeling to extract detailed information contained within our previously obtained high-resolution patch-clamp time-resolved capacitance recordings to produce the first model of adiponectin exocytosis/secretion that combines all mechanistic knowledge deduced from electrophysiological experimental series. This model demonstrates that our previous understanding of the role of intracellular ATP in the control of adiponectin exocytosis needs to be revised to include an additional ATP-dependent step. Validation of the model by introduction of data of secreted adiponectin yielded a very close resemblance between the simulations and experimental results. Moreover, we could show that Ca2+-dependent adiponectin endocytosis contributes to the measured capacitance signal, and we were able to predict the contribution of endocytosis to the measured exocytotic rate under different experimental conditions. In conclusion, using mathematical modeling of published and newly generated data, we have obtained estimates of adiponectin exo- and endocytosis rates, and we have predicted adiponectin secretion. We believe that our model should have multiple applications in the study of metabolic processes and hormonal control thereof.
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| 9. |
- Jonsson, Amanda, et al.
(författare)
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Chemical delivery array with millisecond neurotransmitter release
- 2016
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Ingår i: Science Advances. - Washington : American Association for the Advancement of Science (A A A S). - 2375-2548. ; 2:11
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Tidskriftsartikel (refereegranskat)abstract
- Technologies that restore or augment dysfunctional neural signaling represent a promising route to deeper understanding and new therapies for neurological disorders. Because of the chemical specificity and subsecond signaling of the nervous system, these technologies should be able to release specific neurotransmitters at specific locations with millisecond resolution. We have previously demonstrated an organic electronic lateral electrophoresis technology capable of precise delivery of charged compounds, such as neurotransmitters. However, this technology, the organic electronic ion pump, has been limited to a single delivery point, or several simultaneously addressed outlets, with switch-on speeds of seconds. We report on a vertical neurotransmitter delivery device, configured as an array with individually controlled delivery points and a temporal resolution of 50 ms. This is achieved by supplementing lateral electrophoresis with a control electrode and an ion diode at each delivery point to allow addressing and limit leakage. By delivering local pulses of neurotransmitters with spatiotemporal dynamics approaching synaptic function, the high-speed delivery array promises unprecedented access to neural signaling and a path toward biochemically regulated neural prostheses.
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| 10. |
- Brusselaers, Nicolas, 1993-
(författare)
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The impact of off-site construction transport on air quality
- 2023
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Bok (refereegranskat)abstract
- While transport is inevitable in our economy and daily lives, it also engenders negative effects on the society and environment. The effects of air pollution are responsible for more than 364,200 premature deaths in Europe each year. Most urban areas still exceed the NOx and PM WHO air quality guidelines, of which a large share of pollutants is attributable to freight transport. The construction sector forms no exception, as it intrinsically strongly relies on off-site logistics activities, i.e. transports to and from sites. Although construction works lead to an urban economic uptake on the long-haul, the environmental nuisances from construction logistic (CL) activities during the works have so far been overlooked. This thesis focuses on the air quality impact of off-site construction transport, covering four main parts. First, as there is a lack of knowledge within cities on how to set construction transport demands and how to involve actors in these processes, a stakeholder framework is presented. Next, I identify the available and required transport data (and digitization possibilities) to assess the sector’s environmental impact, such as On-Board Units. Secondly, impact assessments were conducted across various construction supply chain implementations, on single-site, city-wide and national level. Hence, a methodological approach to derive construction-related vehicles from Heavy-Goods Vehicle (HGV) traffic based on algorithmic and geospatial analyses is proposed. Results indicate that construction transport represents 26.40% of total HGV traffic in the Brussels-Capital Region (BCR), generating €45,631.85 of external costs per workday, and 17.58% in Belgium (or €1.45mio per day). Subsequently, the framework was deployed to assess the transport performance of the multimodal Brussels Construction Consolidation Centre. The use of this setup can mitigate external costs by up to 59% compared to business-as-usual operations, most notably on congestion and climate change costs. However, improvements are necessary to tackle local emissions, attributable to less performant -yet ubiquitous- vessel engines. Air pollution damage costs also remain high on city level analyses, with CL inflicting €55,123.07 per month (or €2,505.59 per workday) in the BCR. A fortiori, with the growing concern on urban air quality, this raises the question of where, when and by whom the most exposure costs are inflicted. So far, the geo-temporal link between the emitting freight vehicle and its receptor densities was considered static. The third part introduces a dynamic impact-pathway approach, highlighting that PM & NO2 source impacts engender €61.604 of health costs in the BCR each day. Large differences were found on the local level compared to the traditional static approach, indicating that the proposed dynamic methodology should be used for micro-scale analyses (on link, building or neighborhood level). Striking is that vulnerable population segments such as toddlers, school children and elderly, who are more sensible to the effects of air pollution, incur 60.28% of the total health costs, although these segments represent only a quarter of the BCR population. Moreover, a strong overlap was found between the receptor’s presence (in particular children) and peak freight traffic movements. The fourth part investigates the exposure effects when off-site construction transport flows are spatiotemporally rerouted around air pollution hotspots. Although an increase in emissions is observed due to higher travelled distances and slower driving speeds, results show that the inflicted health costs can be mitigated up to 25.53%. Conclusively, this study suggests to decouple policies from absolute transport emissions and focus on the actual health impact, considering the spatiotemporal relationship of both emissions and receptors. Although tailoring a one-size-fits-all construction logistic plan can initially prove to be difficult due to the unique character of each construction site’s supply chain, the conducted studies also show that this individual complexity can be overcome by overall better integrated urban transport planning, and can ultimately lead to significant sustainability benefits.
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