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> Lindblad Birgitta Ejdervik 1955 >
Intensity of smokin...
Intensity of smoking and smoking cessation in relation to risk of cataract extraction : a prospective study of women
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- Lindblad, Birgitta Ejdervik, 1955- (författare)
- Karolinska Institutet
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- Håkansson, Niclas (författare)
- Karolinska Institutet
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- Svensson, Hanna (författare)
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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- Philipson, Bo (författare)
- Stockholm Eye Clinic, H. M. Queen Sophia Hospital, Stockholm, Sweden
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- Wolk, Alicja (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2005-07-01
- 2005
- Engelska.
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Ingår i: American Journal of Epidemiology. - : Oxford University Press. - 0002-9262 .- 1476-6256. ; 162:1, s. 73-79
- Relaterad länk:
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Abstract
Ämnesord
Stäng
- The authors investigated the association of smoking and smoking cessation with the incidence of cataract extraction in a population-based prospective cohort study. A total of 34,595 women aged 49-83 years in the Swedish Mammography Cohort were followed from September 1997 through June 2002. Information on smoking, diet, and other lifestyle factors was collected through a self-administered questionnaire. A total of 2,128 cases of age-related cataract extraction were identified. Relative risks were estimated as rate ratios using Cox proportional hazards models. The authors observed a significant dose-response association between intensity of smoking and risk of cataract extraction (among current smokers, p for trend = 0.02; among past smokers, p for trend = 0.0002). After cessation of smoking, the risk decreased with time. Among women with a moderate lifetime smoking intensity (6-10 cigarettes/day), the relative risk was not significantly different from the risk among never smokers 10 years after smoking cessation. Among women who had smoked more intensively (>10 cigarettes/day), after 20 years of nonsmoking the increased risk became small and no longer statistically significant in comparison with never smokers (for trend over time, p < 0.0001). This prospective study confirmed smoking as a risk factor for cataract, with a dose response for smoking intensity. Smoking cessation predicts reduced risk over time, but a longer period of time is needed with a higher smoking intensity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Nyckelord
- cataract; cohort studies; smoking; smoking cessation
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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