| 1. |
- Rylance, Rebecca Tremain, et al.
(author)
-
Patient-oriented risk score for predicting death 1 year after myocardial infarction : the SweDen risk score
- 2022
-
In: Open Heart. - : BMJ. - 2053-3624. ; 9:2
-
Journal article (peer-reviewed)abstract
- OBJECTIVES: Our aim was to derive, based on the SWEDEHEART registry, and validate, using the Western Denmark Heart registry, a patient-oriented risk score, the SweDen score, which could calculate the risk of 1-year mortality following a myocardial infarction (MI).METHODS: The factors included in the SweDen score were age, sex, smoking, diabetes, heart failure and statin use. These were chosen a priori by the SWEDEHEART steering group based on the premise that the factors were information known by the patients themselves. The score was evaluated using various statistical methods such as time-dependent receiver operating characteristics curves of the linear predictor, area under the curve metrics, Kaplan-Meier survivor curves and the calibration slope.RESULTS: The area under the curve values were 0.81 in the derivation data and 0.76 in the validation data. The Kaplan-Meier curves showed similar patient profiles across datasets. The calibration slope was 1.03 (95% CI 0.99 to 1.08) in the validation data using the linear predictor from the derivation data.CONCLUSIONS: The SweDen risk score is a novel tool created for patient use. The risk score calculator will be available online and presents mortality risk on a colour scale to simplify interpretation and to avoid exact life span expectancies. It provides a validated patient-oriented risk score predicting the risk of death within 1 year after suffering an MI, which visualises the benefit of statin use and smoking cessation in a simple way.
|
|
| 2. |
- Yndigegn, Troels, et al.
(author)
-
Design and rationale of randomized evaluation of decreased usage of beta-blockers after acute myocardial infarction (REDUCE-AMI)
- 2022
-
In: European Heart Journal - Cardiovascular Pharmacotherapy. - : Oxford University Press. - 2055-6837 .- 2055-6845. ; 9:2, s. 192-197
-
Journal article (peer-reviewed)abstract
- BACKGROUND: Most trials showing benefit of beta-blocker treatment after myocardial infarction (MI) included patients with large MIs and are from an era before modern biomarker-based MI diagnosis and reperfusion treatment. The aim of the Randomized Evaluation of Decreased Usage of betabloCkErs after Acute Myocardial Infarction (REDUCE-AMI) trial is to determine whether long-term oral beta-blockade in patients with an acute MI and preserved left ventricular ejection fraction (EF) reduces the composite endpoint of death of any cause or recurrent MI.METHODS: It is a registry-based, randomized, parallel, open-label, multicenter trial performed at 38 centers in Sweden, one center in Estonia and six centers in New Zealand. About 5000 patients with an acute MI who have undergone coronary angiography and with EF ≥ 50% will be randomized to long-term treatment with beta-blockade or not. The primary endpoint is the composite endpoint of death of any cause or new non-fatal MI. There are several secondary endpoints, including all-cause death, cardiovascular death, new MI, readmission because of heart failure and atrial fibrillation, symptoms, functional status, health related quality of life after 6-10 weeks and after 1 year of treatment. Safety endpoints are bradycardia, AV-block II-III, hypotension, syncope or need for pacemaker, asthma or chronic obstructive pulmonary disease and stroke.CONCLUSION: The results from REDUCE-AMI will add important evidence regarding the effect of beta-blockers in patients with MI and preserved EF and may change guidelines and clinical practice.
|
|
| 3. |
|
|
| 4. |
- Perk, Joep, 1945-, et al.
(author)
-
Ny vårdmodell för prevention efter akut kranskärlssjukdom
- 2016
-
In: Läkartidningen. - : Swedish Medical Association. - 0023-7205 .- 1652-7518. ; 113:51-52, s. 1-3
-
Journal article (other academic/artistic)abstract
- Kardiologföreningens arbetsgrupp för levnadsvanor och arbetsgruppen för SPICI-studien har tillsammans med Riksförbundet HjärtLung tagit fram en ny vårdmodell för prevention/rehabilitering vid kranskärlssjukdom.
|
|
| 5. |
|
|
| 6. |
- Perk, Joep, et al.
(author)
-
Study of patient information after percutaneous coronary intervention (SPICI) : should prevention programmes become more effective?
- 2015
-
In: EuroIntervention. - : EuroPCR. - 1774-024X .- 1969-6213. ; 10:11, s. e1-e7
-
Journal article (peer-reviewed)abstract
- Aims: This cross-sectional observational study was designed to evaluate the uptake and outcome of patient education after percutaneous coronary intervention (PCI).Methods and results: A questionnaire containing 41 items was handed out to consecutive patients from randomly selected Swedish hospitals after PCI. Questions concerned the patient's attribution of the cause of the cardiac event, perception of the information provided by physicians and nurses, and a self-assessment of changes in lifestyle post PCI regarding tobacco, physical activity, food habits and stress. Replies were obtained from 1,073 patients (reply rate 67%). Non-modifiable risk factors (age, heredity) were attributed a higher rate as the cause of disease compared to modifiable factors (smoking, physical activity, food habits). Most patients (67%) perceived they were cured, and 38% perceived from the given information that there was no need to change their habits. A mere 27% reported that they still had cardiovascular disease and needed behavioural change. After PCI, 16% continued to use tobacco; half of these were offered smoking cessation support. In spite of an 80% referral rate to cardiac rehabilitation, one out of two patients did not enrol. Fewer than half were regularly physically active. Nutritional counselling was provided to 71%, but only 40% changed food habits. Stress management programmes were rarely provided.Conclusions: Current preventive practice scarcely meets the challenge posed by the progress in modern invasive cardiology. The Study of Patient Information after percutaneous Coronary Intervention (SPICI) motivates an in-depth revision and adaptation of cardiac rehabilitation programmes in order to improve patient understanding of the disease, and to support greater compliance with a cardioprotective lifestyle.
|
|
| 7. |
- Thomasson, Joakim, et al.
(author)
-
Ett litet stycke av Helsingborg : Om flytt och framväxt av stadskvarteren på Fredriksdal
- 2015
-
In: Fredriksdal : museer och trädgårdar - museer och trädgårdar. - 0440-663X. - 918727437X ; 40, s. 197-217
-
Book chapter (pop. science, debate, etc.)abstract
- A piece of Helsingborg – about the moving of older buildings from the town and the making of an urban area at the Fredriksdal open-air museum The article tells the different stories of how fifteen houses, which during a period from the late 1930s until the 1960s, were moved from the town centre to the open-air museum at Fredriksdal, a part of the municipality museum. It depicts the struggle between modernisation and preservation of old neighbourhoods in the city centre. If older precious buildings had to be demolished, it was up to the museums officials to at least document them in a proper way. Already in the beginning of the 20th century there existed a belief that buildings could be preserved by moving them to another place. It turned out to be much more complicated and more expensive, to move and rebuild townhouses than buildings from the countryside. The first part of the article describes the power play between the museum officials, striving politicians and building contractors. This concerned which buildings should be preserved in-situ, as well as which ones that should be moved to the museum and how this could be funded. The second part explores the process from documentation on the original site to the rebuilding at the open-air museum. What was documented, which building materials were preserved and then reused, which actors were involved and how they interacted are some of the questions that are asked. The end result is, despite the museums ambitions for authenticity and quest for scientific procedures in handling the moves, that the houses are quite different from the ones that were deconstructed.
|
|
| 8. |
|
|
