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Sökning: L4X0:0277 786X

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  • Harvey, Christopher, et al. (författare)
  • High-energy gamma-ray beams from nonlinear Thomson and Compton scattering in the ultra-intense regime
  • 2015
  • Ingår i: Proceedings of SPIE - Relativistic Plasma Waves and Particle Beams as Coherent and Incoherent Radiation Sources; Prague; Czech Republic; 15-16 April 2015. - 0277-786X. - 978-1-62841-630-5 ; 9509
  • Konferensbidrag (refereegranskat)abstract
    • We consider the Thomson and Compton scattering of high-energy electrons n an intense laser pulse. Our simulations show that energy losses due o radiation reaction cause the emitted radiation to be spread over a roader angular range than the case without these losses included. We xplain this in terms of the effect of these energy losses on the article dynamics. Finally, at ultra-high intensities, i.e. fields with dimensionless parameter a(0)similar to 200, the energy of the ission pectrum is significantly reduced by radiation reaction and also the lassical and QED results begin to differ. This is found to be due to he classical theory overestimating the energy loss of the electrons. uch findings are relevant to radiation source development involving e ext generation of high-intensity laser facilities.
  • Infahsaeng, Yingyot, et al. (författare)
  • Transient photocurrent of bulk heterojunction solar cell characterized by ns-laser and sub-ms LED
  • 2015
  • Ingår i: Proceedings of SPIE. - SPIE. - 0277-786X .- 1996-756X. ; 9659, s. UNSP 96591C
  • Konferensbidrag (refereegranskat)abstract
    • We measure the transient photocurrent of APFO3:PCBM bulk heterojunction solar cells illuminated with ns-laser and sub-ms LED light sources. The ratio of the number of collective charges to the number of excited photon (external quantum efficiency, EQE) and the transient photocurrent fall times have been carried out with difference pulse durations and fluences. The EQEs characterized by ns-laser source are shown to obey the bimolecular recombination at high excitation fluences. The increasing of transient photocurrent fall times suggests that the fall times of free charge carriers are effected by deep trap density of state (DoS) and thus the free charge carriers have a sufficient time for bimolecular recombination at short circuit condition. At the same fluences, however, the EQEs characterized by sub-ms LED sources exhibit an excitation fluences independence of EQE. The transient photocurrent fall times with sub-ms LED sources are rather constant when the excitation fluences increases indicating that the deep trap DoS has less effect at short circuit condition for longer pulse duration.
  • Hamngren, C., et al. (författare)
  • Design and evaluation of a microfluidic system for inhibition studies of yeast cell signaling
  • 2012
  • Ingår i: Proceedings of SPIE - The International Society for Optical Engineering. Optical Trapping and Optical Micromanipulation IX, San Diego, 12-16 August 2012. - 0277-786X. - 978-08-19-49175-6 ; 8458
  • Konferensbidrag (refereegranskat)abstract
    • In cell signaling, different perturbations lead to different responses and using traditional biological techniques that result in averaged data may obscure important cell-to-cell variations. The aim of this study was to develop and evaluate a four-inlet microfluidic system that enables single-cell analysis by investigating the effect on Hog1 localization post a selective Hog1 inhibitor treatment during osmotic stress. Optical tweezers was used to position yeast cells in an array of desired size and density inside the microfluidic system. By changing the flow rates through the inlet channels, controlled and rapid introduction of two different perturbations over the cell array was enabled. The placement of the cells was determined by diffusion rates flow simulations. The system was evaluated by monitoring the subcellular localization of a fluorescently tagged kinase of the yeast "High Osmolarity Glycerol" (HOG) pathway, Hog1-GFP. By sequential treatment of the yeast cells with a selective Hog1 kinase inhibitor and sorbitol, the subcellular localization of Hog1-GFP was analysed on a single-cell level. The results showed impaired Hog1-GFP nuclear localization, providing evidence of a congenial design. The setup made it possible to remove and add an agent within 2 seconds, which is valuable for investigating the dynamic signal transduction pathways and cannot be done using traditional methods. We are confident that the features of the four-inlet microfluidic system will be a valuable tool and hence contribute significantly to unravel the mechanisms of the HOG pathway and similar dynamic signal transduction pathways.
  • Maziz, Ali, et al. (författare)
  • Lab on chip microdevices for cellular mechanotransduction in urothelial cells
  • 2016
  • Ingår i: Proc. SPIE 9798, Electroactive Polymer Actuators and Devices (EAPAD) 2016. - SPIE - International Society for Optical Engineering. - 978-1-5106-0039-3 ; s. 97981R-1-97981R-9
  • Konferensbidrag (refereegranskat)abstract
    • Cellular mechanotransduction is crucial for physiological function in the lower urinary tract. The bladder is highly dependent on the ability to sense and process mechanical inputs, illustrated by the regulated filling and voiding of the bladder. However, the mechanisms by which the bladder integrates mechanical inputs, such as intravesicular pressure, and controls the smooth muscles, remain unknown. To date no tools exist that satisfactorily mimic in vitro the dynamic micromechanical events initiated e.g. by an emerging inflammatory process or a growing tumour mass in the urinary tract. More specifically, there is a need for tools to study these events on a single cell level or in a small population of cells. We have developed a micromechanical stimulation chip that can apply physiologically relevant mechanical stimuli to single cells to study mechanosensitive cells in the urinary tract. The chips comprise arrays of microactuators based on the electroactive polymer polypyrrole (PPy). PPy offers unique possibilities and is a good candidate to provide such physiological mechanical stimulation, since it is driven at low voltages, is biocompatible, and can be microfabricated. The PPy microactuators can provide mechanical stimulation at different strains and/or strain rates to single cells or clusters of cells, including controls, all integrated on one single chip, without the need to preprepare the cells. This paper reports initial results on the mechano-response of urothelial cells using the micromechanical stimulation chips. We show that urothelial cells are viable on our microdevices and do respond with intracellular Ca2+ increase when subjected to a micro-mechanical stimulation.
  • Ringaby, Erik, et al. (författare)
  • Co-aligning Aerial Hyperspectral Push-broom Strips for Change Detection
  • 2010
  • Ingår i: Proc. SPIE 7835, Electro-Optical Remote Sensing, Photonic Technologies, and Applications IV. - SPIE - International Society for Optical Engineering. - 978-0-8194-8353-9 ; s. Art.nr. 7835B-36
  • Konferensbidrag (refereegranskat)abstract
    • We have performed a field trial with an airborne push-broom hyperspectral sensor, making several flights over the same area and with known changes (e.g., moved vehicles) between the flights. Each flight results in a sequence of scan lines forming an image strip, and in order to detect changes between two flights, the two resulting image strips must be geometrically aligned and radiometrically corrected. The focus of this paper is the geometrical alignment, and we propose an image- and gyro-based method for geometric co-alignment (registration) of two image strips. The method is particularly useful when the sensor is not stabilized, thus reducing the need for expensive mechanical stabilization. The method works in several steps, including gyro-based rectification, global alignment using SIFT matching, and a local alignment using KLT tracking. Experimental results are shown but not quantified, as ground truth is, by the nature of the trial, lacking.
  • Svensson, Thomas, et al. (författare)
  • Radiometric uncertainty of radiance measured with infrared cameras under variable ambient conditions
  • 2015
  • Ingår i: MODELING ASPECTS IN OPTICAL METROLOGY V. - Society of Photo-optical Instrumentation Engineers (SPIE). - 978-1-62841-686-2
  • Konferensbidrag (refereegranskat)abstract
    • Radiometric calibration and non-uniformity correction are key operations in a signature measurement, which is a special challenge in the infrared range where a large number of parameters need to be characterized. The radiation hitting the cameras pixels will not only be due to the target, but will also depend on the atmosphere and optical components like lens and spectral filters. To obtain broadband radiative properties of a target, the spectral properties of these components must be accurately characterized. In addition to signal contributions from the incident radiation, the pixels digital numbers will also depend on the individual responses of the pixels. Results are presented for an infrared camera of the following parameters: stabilization period, dynamic response, dynamic range, ambient temperature dependence and non-uniformity. In radiometric calibrations using area blackbody sources, an estimate of the sensor signal is obtained by pixel averaging (which reduces the influence of non-uniformity), and the spectral distributions of the sources are known (via the Planck distribution). These conditions do not normally apply for signature measurements e.g. of small hot spots involving only a few pixels. The measurement uncertainty is compared between calibrations based on mean values and pixel-wise calibration. A discussion is given of the effects of unknown spectral distributions on the measurement uncertainty.
  • Willander, Magnus, et al. (författare)
  • UV detectors and LEDs in different metal oxide nanostructures
  • 2014
  • Konferensbidrag (refereegranskat)abstract
    • Different composite nanostructures based pn-junctions have been synthesized using the low temperature hydrothermal chemical growth. The composite nanostructures based pn junctions demonstrated here include p-NiO/n-ZnO, p-CuO/n-ZnO, and p-NiO/n-TiO2. Structural characterization of these composite nanostructures based pn-junctions was performed by different complementary tools and the results indicated that reasonable device quality crystals have been achieved. His act was also confirmed by the rectifying electrical behavior observed from these junctions. Further, the different composite nanostructures based junctions were used to demonstrate UV detectors and visible light emitting diodes (LEDs) operating with acceptable performance.
  • Xu, Tianhua, et al. (författare)
  • Phase noise mitigation in coherent transmission system using a pilot carrier
  • 2011
  • Ingår i: Optical Transmission Systems, Subsystems, and Technologies IX. - SPIE - International Society for Optical Engineering. - 9780819489579
  • Konferensbidrag (refereegranskat)abstract
    • In this paper, we investigate the phase noise elimination employing an optical pilot carrier in the high speed coherent transmission system considering the equalization enhanced phase noise (EEPN). The numerical simulations are performed in a 28-Gsymbol/s quadrature phase shift keying (QPSK) coherent system with a polarization multiplexed pilot carrier. The carrier phase estimation is implemented by the one-tap normalized least mean square (NLMS) filter and the differential phase detection, respectively. Simulation results demonstrate that the application of the optical pilot carrier is very effective for the intrinsic laser phase noise cancellation, while is less efficient for the EEPN mitigation.
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