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- Bill-Axelson, Anna, et al.
(författare)
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Radical prostatectomy versus watchful waiting in early prostate cancer.
- 2011
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Ingår i: The New England journal of medicine. - : Massachussetts Medical Society. - 1533-4406 .- 0028-4793. ; 364:18, s. 1708-17
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Forskningsöversikt (refereegranskat)abstract
- In 2008, we reported that radical prostatectomy, as compared with watchful waiting, reduces the rate of death from prostate cancer. After an additional 3 years of follow-up, we now report estimated 15-year results.
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- Swedberg, Karl, 1944, et al.
(författare)
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Challenges to Data Monitoring Committees When Regulatory Authorities Intervene
- 2016
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Ingår i: New England Journal of Medicine. - 0028-4793 .- 1533-4406. ; 374, s. 1580-1584
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Forskningsöversikt (refereegranskat)abstract
- New pharmaceutical agents are best evaluated in randomized, controlled clinical trials in which both the safety of participants and the adequacy of conduct are monitored by an independent data monitoring committee as described in reports from regulatory organizations.1-3 A data monitoring committee can recommend discontinuation of a trial because of futility or because of overwhelming benefit or unacceptable harm associated with an agent, and it can recommend modification of a trial for safety. The data monitoring committee should review relevant contributory information from parallel studies4-8 in order to make appropriate recommendations. Regulatory authorities also must evaluate trial data, . . .
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- Enerbäck, Sven, 1958
(författare)
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The origins of brown adipose tissue.
- 2009
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Ingår i: The New England journal of medicine. - 1533-4406. ; 360:19, s. 2021-3
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Forskningsöversikt (refereegranskat)
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