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Sökning: L773:0030 2414 OR L773:1423 0232 > Forskningsöversikt > Carcinosarcoma of t...

Carcinosarcoma of the ovary : Analysis of 13 cases and review of the literature

Loizzi, Vera (författare)
University of Bari Aldo Moro
Cormio, Gennaro (författare)
University of Bari Aldo Moro
Camporeale, Anna (författare)
University of Bari Aldo Moro
visa fler...
Falagario, Maddalena (författare)
Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,University of Bari Aldo Moro
De Mitri, Paola (författare)
University of Bari Aldo Moro
Scardigno, Doriana (författare)
University of Bari Aldo Moro
Putignano, Giuseppe (författare)
University of Bari Aldo Moro
Selvaggi, Luigi E. (författare)
University of Bari Aldo Moro
visa färre...
 (creator_code:org_t)
2011-06-14
2011
Engelska.
Ingår i: Oncology. - : S. Karger AG. - 0030-2414 .- 1423-0232. ; 80:1-2, s. 102-106
  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
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  • Objectives: The aim of this study was to evaluate our experience with patients affected by ovarian carcinosarcoma. Patients and Methods: During a 16-year period, data on 13 patients with ovarian carcinosarcoma were collected. They were obtained from hospital charts and follow-up visits. Survival curves were estimated by the Kaplan-Meier method and compared using the log-rank test. All tests were two-tailed with p values <0.05 considered significant. Results: Our study was conducted on 13 patients with ovarian carcinosarcoma referred to our unit, during an observation time of about 16 years (March 1994 to October 2010). An improved survival was observed in patients treated with optimal cytoreductive surgery with residual tumors <2 cm (30 vs. 5 months; p = 0.042). All patients underwent adjuvant chemotherapy based on the combination of cisplatin, epirubicin and ifosfamide (PEI) and taxol and carboplatin (TAX-CBDCA) regimen. Overall survival of the patient population was 17 months. Conclusions: Similarly to data published in the literature, we observed that malignant mixed mullerian ovarian tumors are very aggressive and are usually diagnosed at an advanced age and at an advanced stage of disease. Therefore, due to the rarity of the tumor we would like to add our series to those already published in the literature, although our treatment recommendations are actually based upon retrospective studies with a small patient population.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Malignant mixed mullerian tumor of the ovary
Ovarian carcinosarcoma

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