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Sex Differences in ...
Sex Differences in Stroke Care and Outcome 2005-2018 : Observations From the Swedish Stroke Register
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- Eriksson, Marie, Professor (author)
- Umeå universitet,Statistik,Umeå Univ, Dept Stat, USBE, S-90187 Umeå, Sweden.
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- Åsberg, Signild, 1972- (author)
- Uppsala universitet,Institutionen för neurovetenskap
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- Stibrant Sunnerhagen, Katharina, 1957 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
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- von Euler, Mia, 1967- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Örebro Univ, Sch Med, Örebro, Sweden.
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Riksstroke Collaboration, - (contributor)
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(creator_code:org_t)
- AHA Journals, 2021
- 2021
- English.
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In: Stroke. - : AHA Journals. - 0039-2499 .- 1524-4628. ; 52:10, s. 3233-3242
- Related links:
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https://doi.org/10.1...
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Abstract
Subject headings
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- BACKGROUND AND PURPOSE: Previous studies of stroke management and outcome in Sweden have revealed differences between men and women. We aimed to analyze if differences in stroke incidence, care, and outcome have altered over time.METHODS: All stroke events registered in the Swedish Stroke Register 2005 to 2018 were included. Background variables and treatment were collected during the acute hospital stay. Survival data were obtained from the national cause of death register by individual linkage. We used unadjusted proportions and estimated age-adjusted marginal means, using a generalized linear model, to present outcome.RESULTS: We identified 335 183 stroke events and a decreasing incidence in men and women 2005 to 2018. Men were on average younger than women (73.3 versus 78.1 years) at stroke onset. The age-adjusted proportion of reperfusion therapy 2005 to 2018 increased more rapidly in women than in men (2.3%-15.1% in men versus 1.4%-16.9% in women), but in 2018, women still had a lower probability of receiving thrombolysis within 30 minutes. Among patients with atrial fibrillation, oral anticoagulants at discharge increased more rapidly in women (31.2%-78.6% in men versus 26.7%-81.9% in women). Statins remained higher in men (36.9%-83.7% in men versus 32.3%-81.2% in women). Men had better functional outcome and survival after stroke. After adjustment for women's higher age, more severe strokes, and background characteristics, the absolute difference in functional outcome was <1% and survival did not differ.CONCLUSIONS: Stroke incidence, care, and outcome show continuous improvements in Sweden, and previously reported differences between men and women become less evident. More severe strokes and older age in women at stroke onset are explanations to persisting differences.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Healthcare disparities
- mortality
- patient reported outcome
- secondary prevention
- sex
- stroke
- thrombolysis
- healthcare disparities; mortality; patient reported outcome; secondary prevention; sex; stroke; thrombolysis
Publication and Content Type
- ref (subject category)
- art (subject category)
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