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Träfflista för sökning "L773:0250 7005 OR L773:1791 7530 srt2:(1990-1994);pers:(Aspegren K)"

Sökning: L773:0250 7005 OR L773:1791 7530 > (1990-1994) > Aspegren K

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1.
  • Olsson, H., et al. (författare)
  • Increased plasma prolactin levels in a group of men with breast cancer - a preliminary study
  • 1990
  • Ingår i: Anticancer research. - 0250-7005. ; 10:1, s. 59-62
  • Tidskriftsartikel (refereegranskat)abstract
    • Gonadal and hypophyseal hormones were investigated in 15 males with breast cancer and 15 tumour referents, on average 1 month postoperatively. Plasma prolactin was found to be significantly more often elevated in men with breast cancer compared with referents (p <0.005). Another group of men with breast cancer disclosed a tendency for lower S-FSH levels compared with the referents (p <0.01). No significant difference was seen between cases and referents regarding S-LH, p-estradiol or p-testosterone. The size of the primary breast tumour was correlated with a higher prolactin level. The findings lend support to a theory implicating prolactin and possibly prolactinomas as a risk factor for the disease in males.
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2.
  • Ranstam, J., et al. (författare)
  • Survival in breast cancer and age at start of oral contraceptive usage
  • 1991
  • Ingår i: Anticancer research. - 0250-7005. ; 11:6, s. 2043-2046
  • Tidskriftsartikel (refereegranskat)abstract
    • In general, findings in studies on oral contraceptives (OCs) and breast cancer have not indicated prognosis to be worse among users of OCs. In few studies, however, has age at the start of OC usage been considered as a prognostic factor. In the present study prognosis in breast cancer is compared with OC usage particularly with age at the start of OC usage among 193 consecutive patients at the Department of Oncology University Hospital Lund. An earlier series of 193 breast cancer patients at Malmo General Hospital is included for comparisons. In the Lund series five-year survival was 62% among women who started to use OCs before the age of 20, 78% among those who started to use OCs between the ages of 20 and 25, and 86% among non-users and those who started to use OCs after the age of 25 (p = 0.009 test for homogeneity). Although age was found to be a prognostic factor in the Lund series (RR = 0.90, p = 0.001) this was not so in the earlier (older) Malmo series. The relationship with age differed significantly between the two series (p = 0.003) suggesting the apparent effect of age at diagnosis to be a cohort effect due to the introduction of OCs during the sixties. The age-specific relationship between survival and OC usage would seem to indicate the presence of a biological mechanism in which OCs may participate during precancerous and early stages of breast cancer.
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  • Resultat 1-2 av 2
Typ av publikation
tidskriftsartikel (2)
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refereegranskat (2)
Författare/redaktör
Olsson, H. (2)
Ranstam, J (2)
Aspegren, K (2)Ta bort avgränsningen
Garne, J P (1)
Janzon, L. (1)
Gullberg, B (1)
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Alm, P (1)
Jonsson, P. E. (1)
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Lunds universitet (2)
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Engelska (2)
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Medicin och hälsovetenskap (1)

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