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Sökning: L773:1398 9995 > Wickman M

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  • Egmar, Ann-Charlotte, et al. (författare)
  • Deposition of cat (Fel d 1), dog (Can f 1), and horse allergen over time in public environments--a model of dispersion
  • 1998
  • Ingår i: Allergy. European Journal of Allergy and Clinical Immunology. - : John Wiley & Sons. - 0105-4538 .- 1398-9995. ; 53:10, s. 957-961
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The occurrence and accumulation over time in public environments of cat, dog, and horse allergens was evaluated.METHODS: Concentrations of animal danders were analyzed by ELISA and countercurrent immunoelectrophoresis (CCIE).RESULTS: Among factory-new mattresses, 15/17 contained detectable levels of cat and/or dog allergen, whereas no horse allergen was found although six of the mattresses were stuffed with horsehair. Dust from 15 used mattresses contained significantly higher concentrations of Fe1 d 1 and Can f 1 than the factory-new ones (P < 0.001). Allergen concentrations and titers correlated to the period of time that the mattresses had been tried by customers; rs = 0.52-0.77, P = 0.04-0.001 (cat), rs = 0.38-0.48, P = 0.15-0.08 (dog), and rs = 0.64-0.74, P = 0.008-0.003 (horse). The increase over time occurred rapidly in highly frequented stores and after 3 weeks reached concentrations that have been found in homes where furred pets had formerly been kept or even the lower allergen scale of homes where pets were currently kept.CONCLUSIONS: The dispersion of allergens from furred animals to pet-free public places is likely to occur by deposition from people who have been in direct or indirect contact with pets, and high levels of such allergens seem to accumulate in a short period of time.
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  • Svartengren, M, et al. (författare)
  • Atopy-related diseases
  • 2001
  • Ingår i: Allergy. - : Wiley. - 0105-4538 .- 1398-9995. ; 56:4, s. 267-269
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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  • Lilja, G, et al. (författare)
  • The immunology of fetuses and infants
  • 2000
  • Ingår i: Allergy. - : Wiley. - 0105-4538 .- 1398-9995. ; 55:7, s. 589-590
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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  • Asarnoj, A., et al. (författare)
  • IgE to peanut allergen components : relation to peanut symptoms and pollen sensitization in 8-year-olds
  • 2010
  • Ingår i: Allergy. European Journal of Allergy and Clinical Immunology. - : Wiley. - 0105-4538 .- 1398-9995. ; 65:9, s. 1189-1195
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Allergen-specific IgE testing is often performed with crude peanut extract, but the results may be difficult to interpret because of cross-reactions between peanut and other plant allergens. The aim was to investigate IgE reactivity to peanut allergen components in children from a birch-rich region in relation to pollen sensitization and peanut symptoms. Methods: From a birth cohort, clinical parameters were obtained through questionnaires and IgE antibody levels to peanut and birch pollen were measured. Different peanut/birch sensitization phenotypes were defined among 200 selected children. IgE reactivity to peanut and pollen allergen components was analysed using microarray technique. Results: Peanut symptoms were reported in 87% of the children with IgE reactivity to any of the peanut allergens Ara h 1, 2 or 3 but not to Ara h 8 (n = 46) vs 17% of children with IgE reactivity to Ara h 8 but not to Ara h 1, 2 or 3 (n = 23), P < 0.001. Furthermore, symptoms were more severe in children with Ara h 1, 2 or 3 reactivity. Children with IgE reactivity both to Ara h 2 and to Ara h 1 or 3 more often reported peanut symptoms than children with IgE only to Ara h 2 (97% vs 70%, P = 0.016), particularly respiratory symptoms (50% vs 9%, P = 0.002). Conclusions: IgE analysis to peanut allergen components may be used to distinguish between peanut-sensitized individuals at risk of severe symptoms and those likely to have milder or no symptoms to peanut if sensitized to pollen allergens and their peanut homologue allergens.
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  • Resultat 1-10 av 68

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