Sökning: L773:1432 1920
> Knutsson Linda >
Perfusion MRI of br...
Perfusion MRI of brain tumours : a comparative study of pseudo-continuous arterial spin labelling and dynamic susceptibility contrast imaging
-
Järnum, Hanna (författare)
-
Steffensen, Elena G. (författare)
-
- Knutsson, Linda (författare)
- Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
-
visa fler...
-
Fründ, Ernst-Torben (författare)
-
Simonsen, Carsten Wiberg (författare)
-
Lundbye-Christensen, Søren (författare)
-
Shankaranarayanan, Ajit (författare)
-
Alsop, David C. (författare)
-
Jensen, Finn Taagehøj (författare)
-
- Larsson, Elna-Marie (författare)
- Uppsala universitet,Enheten för radiologi
-
visa färre...
-
(creator_code:org_t)
- 2009-10-20
- 2010
- Engelska.
-
Ingår i: Neuroradiology. - : Springer Science and Business Media LLC. - 0028-3940 .- 1432-1920. ; 52:4, s. 307-317
- Relaterad länk:
-
https://europepmc.or...
-
visa fler...
-
http://dx.doi.org/10...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
visa färre...
Abstract
Ämnesord
Stäng
- INTRODUCTION: The purpose of this study was to compare the non-invasive 3D pseudo-continuous arterial spin labelling (PC ASL) technique with the clinically established dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-MRI) for evaluation of brain tumours. METHODS: A prospective study of 28 patients with contrast-enhancing brain tumours was performed at 3 T using DSC-MRI and PC ASL with whole-brain coverage. The visual qualitative evaluation of signal enhancement in tumour was scored from 0 to 3 (0 = no signal enhancement compared with white matter, 3 = pronounced signal enhancement with equal or higher signal intensity than in grey matter/basal ganglia). The extent of susceptibility artefacts in the tumour was scored from 0 to 2 (0 = no susceptibility artefacts and 2 = extensive susceptibility artefacts (maximum diameter > 2 cm)). A quantitative analysis was performed with normalised tumour blood flow values (ASL nTBF, DSC nTBF): mean value for region of interest (ROI) in an area with maximum signal enhancement/the mean value for ROIs in cerebellum. RESULTS: There was no difference in total visual score for signal enhancement between PC ASL and DSC relative cerebral blood flow (p = 0.12). ASL had a lower susceptibility-artefact score than DSC-MRI (p = 0.03). There was good correlation between DSC nTBF and ASL nTBF values with a correlation coefficient of 0.82. CONCLUSION: PC ASL is an alternative to DSC-MRI for the evaluation of perfusion in brain tumours. The method has fewer susceptibility artefacts than DSC-MRI and can be used in patients with renal failure because no contrast injection is needed.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- Magnetic resonance imaging
- Perfusion
- ASL
- DSC-MRI
- Brain neoplasms
- MEDICINE
- MEDICIN
- Brain neoplasms
- DSC-MRI
- ASL
- Magnetic resonance imaging
- Perfusion
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas