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Sökning: L773:1552 5260 > Luleå tekniska universitet

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  • Ngandu, Tiia, et al. (författare)
  • The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)
  • 2022
  • Ingår i: Alzheimer's & Dementia. - : John Wiley & Sons. - 1552-5260 .- 1552-5279. ; 18:7, s. 1325-1334
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: Lifestyle interventions may prevent cognitive decline, but the sufficient dose of intervention activities and lifestyle changes is unknown. We investigated how intervention adherence affects cognition in the FINGER trial (pre-specified subgroup analyses).Methods: FINGER is a multicenter randomized controlled trial examining the efficacy of multidomain lifestyle intervention (ClinicalTrials.gov NCT01041989). A total of 1260 participants aged 60 to 77 with increased dementia risk were randomized to a lifestyle intervention and control groups. Percentage of completed intervention sessions, and change in multidomain lifestyle score (self-reported diet; physical, cognitive, and social activity; vascular risk) were examined in relation to change in Neuropsychological Test Battery (NTB) scores.Results: Active participation was associated with better trajectories in NTB total and all cognitive subdomains. Improvement in lifestyle was associated with improvement in NTB total and executive function.Discussion: Multidomain lifestyle changes are beneficial for cognitive functioning, but future interventions should be intensive enough, and supporting adherence is essential.
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  • Vega Mendoza, Mariana, et al. (författare)
  • Language learning for people living with dementia and their carers: A feasibility study
  • 2021
  • Ingår i: Alzheimer's & Dementia. - : John Wiley & Sons. - 1552-5260 .- 1552-5279. ; 17:S6
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Converging evidence from across the world suggests positive effects of bilingualism on cognitive ageing and dementia, including a ca. 4-6 years delay in the onset of dementia and’or Mild Cognitive Impairment. However, it is less clear whether language learning can also have a positive effect after the onset of dementia. A positive influence would include psychological and social variables, such as patients’ well-being and their relationship with relatives and carers.Method We examined the feasibility and tolerability of language learning for people in early stages of dementia and their family carers in two Scottish Dementia Day Care Centres. A total of 12 people with dementia and 7 family carers participated in the study. All participants had only limited experience of language learning and none were bi-/multilingual. The 2-week courses of beginners Italian were delivered by specially trained tutors from Lingo Flamingo, a social enterprise specialising in language teaching for older learners and learners with Dementia. Before and after the course, we conducted focus group sessions with learners and their carers as well as interviews with teachers and Day Centre care workers.Results Qualitative analyses revealed a positive perception of the courses by patients, carers, and centre managers, impacting both the individual (e.g., boosting self-esteem) and group (e.g., socialising) levels. No adverse effects (e.g., confusion) were reported. The family carers perceived the courses as empowering, as they allowed them to take an active part. The courses led also to a higher attendance in other activities conducted in the Day Care Centre.Conclusions Despite initial fears from professional carers that being confronted with the task of learning a new language might be stressful and lead to frustration and confusion, all participants reported a highly positive experience of the course, including a higher self-esteem and self-confidence as well as establishment of new social contacts and a more positive attitude to other activities of the day care centre. Further studies will be required to determine the optimal frequency, intensity and duration of language courses for people with dementia as well as the best practice of their delivery.
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