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2.
  • Rodriguez, G, et al. (författare)
  • Sex differences in regional cerebral blood flow.
  • 1988
  • Ingår i: Journal of Cerebral Blood Flow and Metabolism. - : SAGE Publications. - 0271-678X .- 1559-7016. ; 8:6, s. 783-789
  • Tidskriftsartikel (refereegranskat)abstract
    • Regional cerebral blood flow was measured by the 133-xenon inhalation method during resting in 38 healthy men and 38 healthy women matched pairwise for age in the range 18-72 years. The results showed 11% higher global flow level in the women in all ages. A similar and significant regression of flow by age was seen for both sexes. The regional flow distribution also showed some sex-related differences. Frontal regions showed an asymmetry in the men with higher values on the right side. The female flows were more symmetric. As a hypothesis, it is suggested that the higher flow level in women may be a systemic phenomenon. In fact, other authors have found a higher cardiac index in females. The sex differences in regional flow pattern might be due to differences in the functional organization of the cortex and/or to differences in the mental processes of the "resting" state.
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3.
  • Wendt, Peter E., et al. (författare)
  • Ethanol reduces asymmetry of visual rCBF responses
  • 1994
  • Ingår i: Journal of Cerebral Blood Flow and Metabolism. - : SAGE Publications Inc.. - 0271-678X .- 1559-7016. ; 14:6, s. 963-973
  • Tidskriftsartikel (refereegranskat)abstract
    • Visual regional CBF (rCBF) responses were measured in 10 healthy male subjects before and after an ethanol dose of 1 g/kg body weight. This dose induces well-established cerebral vasodilatation. However, significant bilateral occipital increases were found in both conditions. Apparently, the coupling between neuronal activity and rCBF is preserved following ethanol. The occipital and posterior parietal flow increases were, however, larger on the right than the left side in the sober state. During inebriation the asymmetry disappeared, possibly representing a more undifferentiated processing of visual information. We propose that ethanol causes a reduced inhibition of the left posterior cortex and a reduction of right-hemisphere information processing.
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