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- Jacobsson, Lars, et al.
(författare)
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Demographics, injury characteristics and outcome of traumatic brain injuries in northern Sweden
- 2007
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Ingår i: Acta Neurologica Scandinavica. - : Hindawi Limited. - 1600-0404 .- 0001-6314. ; 116:5, s. 300-306
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Tidskriftsartikel (refereegranskat)abstract
- Objectives - To describe demographics, injury characteristics and outcome of traumatic brain injury (TBI) in northern Sweden over 10 years. Materials and methods - Data were retrospectively collected on those individuals (n = 332) in Norrbotten, northern Sweden, with a TBI who had been transferred for neurosurgical care from 1992 to 2001. Results - A majority were older men with a mild TBI and an acute or chronic subdural hematoma following a fall. Younger individuals were fewer but had more often a severe TBI from a traffic accident. Most individuals received post-acute care and brain injury rehabilitation. A majority had a moderate or severe disability, but many were discharged back home with no major changes in their physical or social environment. Conclusions - Our data confirm the relationship between age, cause of injury, injury severity and outcome in relation to TBI and underscore the need for prevention as well as the importance of TBI as a cause of long-term disability.
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| 2. |
- Jacobsson, Lars, et al.
(författare)
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Functioning and disability 6-15 years after traumatic brain injuries in northern Sweden
- 2009
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Ingår i: Acta Neurologica Scandinavica. - : Hindawi Limited. - 1600-0404 .- 0001-6314. ; 120:6, s. 389-395
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Tidskriftsartikel (refereegranskat)abstract
- Objectives - To assess long-term functioning and disability after traumatic brain injury (TBI). Material and methods - Individuals (n = 88) in Norrbotten, northern Sweden, who had been transferred for neurosurgical care were assessed with internationally established TBI outcome measures 6-15 years post-injury. Results - There was an improvement in overall outcome from discharge from inpatient rehabilitation to follow-up. Many individuals had a high degree of motor and cognitive functioning, which enabled them to live independently in their own home without assistance, but there remained a disability related to community reintegration and social participation. This affected their productivity and to some degree their marital stability. The remaining disability and reduced productivity were related to the age at injury and the injury severity. Conclusions Our data showed that individuals with a TBI can achieve and maintain a high degree of functioning many years after the injury. Increasing age and a greater injury severity contributed to their long-term disability.
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| 4. |
- Thomas, Ilias, et al.
(författare)
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The effect of continuous levodopa treatment during the afternoon hours
- 2019
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Ingår i: Acta Neurologica Scandinavica. - : John Wiley & Sons. - 0001-6314 .- 1600-0404. ; 139:1, s. 70-75
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this retrospective study was to investigate if patients with PD, who are treated with levodopa‐carbidopa intestinal gel (LCIG), clinically worsen during the afternoon hours and if so, to evaluate whether this occurs in all LCIG‐treated patients or in a sub‐group of patients.Methods: Three published studies were identified and included in the analysis. All studies provided individual response data assessed on the treatment response scale (TRS) and patients were treated with continuous LCIG. Ninety‐eight patients from the three studies fulfilled the criteria. T‐tests were performed to find differences on the TRS values between the morning and the afternoon hours, linear mixed effect models were fitted on the afternoon hours’ evaluations to find trends of wearing‐off, and patients were classified into three TRS categories (meaningful increase in TRS, meaningful decrease in TRS, non ‐meaningful increase or decrease).Results: In all three studies significant statistical differences were found between the morning TRS values and the afternoon TRS values (p‐value <= 0.001 in all studies). The linear mixed effect models had significant negative coefficients for time in two studies, and 48 out of 98 patients (49%) showed a meaningful decrease of TRS during the afternoon hours.Conclusion: The results from all studies were consistent, both in the proportion of patients in the three groups and the value of TRS decrease in the afternoon hours. Based on these findings there seems to be a group of patients with predictable “off” behavior in the later parts of the day.
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