Sökning: L773:1602 1622 OR L773:1757 9996
> Coli Pierluigi >
The effect of a den...
The effect of a dentifrice in the prevention of recurrent aphthous stomatitis.
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- Coli, Pierluigi, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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- Jontell, Mats, 1951 (författare)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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- Hakeberg, Magnus, 1954 (författare)
- Jönköping University,Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. Centrum för oral hälsa
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(creator_code:org_t)
- 2004
- 2004
- Engelska.
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Ingår i: Oral health & preventive dentistry. - 1602-1622. ; 2:2, s. 133-41
- Relaterad länk:
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http://www.ncbi.nlm....
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visa fler...
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https://gup.ub.gu.se...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- PURPOSE: A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the efficacy of an experimental dentifrice on the prevention of recurrent aphthous stomatitis (RAS). MATERIAL AND METHODS: A 3-month pretrial period was used to self-record data pertaining to the frequency, ulcer size, duration, and pain associated with ulcers. Thirty-six participants, who reported at least 3 RAS episodes or 30 days with RAS during the pretrial period, completed the study. Following a stratified randomization for age, sex and disease severity, the participants received the experimental dentifrice (T) or the placebo (C). The test period comprised 3 months of self-evaluation of number of ulcers, size and location. Pain related to RAS was estimated by the use of a Visual Analogue Scale (VAS). RESULTS: Symptoms were found to decrease in both groups when the pretrial and test periods were compared, although no statistical difference was reached in the C group. A statistically significant difference between the two time periods was obtained for the T group concerning the number of days with ulcers (p < 0.025) and VAS (p < 0.010). Of more clinical importance was the observation that 50% of the patients in the T group reported a more than 50% reduction in days with ulcers compared to 17% in the C group. CONCLUSIONS: The dentifrice may be used as a treatment strategy for a subgroup of patients with RAS in view of the low adverse effects and the benefit of using a treatment modality that is a part of daily routines.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- Adolescent
- Adult
- Aged
- Child
- Dentifrices
- analysis
- therapeutic use
- Double-Blind Method
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Pain Measurement
- Placebos
- Stomatitis
- Aphthous
- pathology
- physiopathology
- prevention & control
- Time Factors
- Adolescent
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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