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Sökning: L773:1873 1244

  • Resultat 1-10 av 48
  • [1]2345Nästa
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1.
  • Santos, B., et al. (författare)
  • Control and data acquisition software upgrade for JET gamma-ray diagnostics
  • 2018
  • Ingår i: Fusion engineering and design. - ELSEVIER SCIENCE SA. - 0920-3796 .- 1873-7196. ; 128, s. 117-121
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>The Joint European Torus (JET), the largest magnetic confinement plasma physics experiment in operation, has a large amount of key diagnostics for physics exploration and machine operation, which include several Gamma Ray Diagnostics. The Gamma-Ray Spectrometer (GRS), Gamma Camera (GC) and Gamma-Ray Spectrometer Upgrade (GSU) diagnostics have similar Control and Data Acquisition Systems (CDAQ) based on the Advanced Telecommunication Computing Architecture standard, featuring Field Programmable Gate Arrays for data processing and management. During past JET-EP2 enhancements, the GRS and GC diagnostics were successfully installed and commissioned. However, the installed CDAQ software that interfaces these diagnostics to JET Control and Data Acquisition System is different, requiring higher maintenance costs. Benefiting from the Gamma Camera Upgrade (GCU) and new GSU installation and commissioning, the upgrading of the software and controller hardware used in the GRS and GC was evaluated, aiming at software standardization between all three diagnostics for easier maintenance. This paper describes the software standardization process between the diagnostics towards the usage of the same CDAQ software as well as the same Operating System (OS) for the controllers, which allows the operator to minimize the maintenance time, avoiding the need for system specific expertise. The rationale behind the choice of MARTe framework as CDAQ software and Scientific Linux as OS will also be presented.</p>
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2.
  • Santos, B., et al. (författare)
  • Control and data acquisition software upgrade for JET gamma-ray diagnostics
  • 2018
  • Ingår i: Fusion engineering and design. - ELSEVIER SCIENCE SA. - 0920-3796 .- 1873-7196. ; 128, s. 117-121
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>The Joint European Torus (JET), the largest magnetic confinement plasma physics experiment in operation, has a large amount of key diagnostics for physics exploration and machine operation, which include several Gamma Ray Diagnostics. The Gamma-Ray Spectrometer (GRS), Gamma Camera (GC) and Gamma-Ray Spectrometer Upgrade (GSU) diagnostics have similar Control and Data Acquisition Systems (CDAQ) based on the Advanced Telecommunication Computing Architecture standard, featuring Field Programmable Gate Arrays for data processing and management. During past JET-EP2 enhancements, the GRS and GC diagnostics were successfully installed and commissioned. However, the installed CDAQ software that interfaces these diagnostics to JET Control and Data Acquisition System is different, requiring higher maintenance costs. Benefiting from the Gamma Camera Upgrade (GCU) and new GSU installation and commissioning, the upgrading of the software and controller hardware used in the GRS and GC was evaluated, aiming at software standardization between all three diagnostics for easier maintenance. This paper describes the software standardization process between the diagnostics towards the usage of the same CDAQ software as well as the same Operating System (OS) for the controllers, which allows the operator to minimize the maintenance time, avoiding the need for system specific expertise. The rationale behind the choice of MARTe framework as CDAQ software and Scientific Linux as OS will also be presented.</p>
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  • Axling, Ulrika, et al. (författare)
  • Metabolic effects of whole grain wheat and whole grain rye in the C57BL/6J mouse.
  • 2010
  • Ingår i: Nutrition. - Elsevier. - 1873-1244. ; 26, s. 230-239
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: A diet rich in whole grain cereals is suggested to protect against type 2 diabetes and facilitate body weight regulation. However, little is known about the impact of different cereals and the underlying mechanisms. The objective of this study was to compare the long-term metabolic effects of diets supplemented with whole grain wheat or whole grain rye in the C57BL/6J mouse. METHODS: Mice were fed the whole grain supplements in a low-fat background diet for 22 wk. Oral and intravenous glucose tolerance tests were performed during the study and in vitro insulin secretion assays were performed at the end of the study. Body weight, energy intake, body fat content, and plasma parameters were measured during the study. RESULTS: A dietary supplement of whole grain rye suppressed body weight gain and resulted in significantly decreased adiposity, plasma leptin, total plasma cholesterol, and triacylglycerols compared with a supplement of whole grain wheat. Also, a slight improvement in insulin sensitivity was observed in the rye group compared with the wheat group. The decreases in body weight and adiposity were observed in the absence of differences in energy intake. CONCLUSION: Long-term administration of whole grain rye evokes a different metabolic profile compared with whole grain wheat in the C57BL/6J mouse, the primary difference being that whole grain rye reduces body weight and adiposity compared with whole grain wheat. In addition, whole grain rye slightly improves insulin sensitivity and lowers total plasma cholesterol.
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6.
  • Blomstrand, Eva, et al. (författare)
  • Influence of ingesting a solution of branched-chain amino acids on plasma and muscle concentrations of amino acids during prolonged submaximal exercise.
  • 1996
  • Ingår i: Nutrition (Burbank, Los Angeles County, Calif.). - 0899-9007 .- 1873-1244. ; 12:7-8, s. 485-90
  • Tidskriftsartikel (refereegranskat)abstract
    • <p>On two occasions, seven male endurance-trained cyclists performed sustained exhaustive exercise with reduced muscle glycogen stores. During exercise, the subjects were supplied in random order with an aqueous solution of branched-chain amino acids (BCAA) or flavored water (placebo). Ingestion of BCAA caused the concentration of these amino acids to increase by 135% in the plasma and by 57% in muscle tissue during exercise, whereas in the placebo trial there was no change or a slight decrease in the concentration in plasma and a decrease of 18% in the muscle. The plasma concentration of alanine increased by 48% during exercise when BCAA were ingested, and the increase in the muscle concentration of alanine during exercise was larger (70% versus 31% in the placebo trial), suggesting an increased rate of alanine production. Also, the plasma concentration of arginine increased by 14% during exercise when BCAA were ingested, whereas there was no change during exercise in the placebo trial. There was a smaller decrease in the muscle glutamate concentration during exercise in the BCAA trial (32% versus 47% in the placebo trial; p &lt; 0.05), but, for the remaining amino acids, there was no difference between the BCAA and placebo trials. There was a significant decrease in the muscle glycogen concentration during exercise in the placebo trial, whereas only a small decrease was found in the BCAA trial (28 and 9 mmol/kg wet wt [p &lt; 0.05] in the placebo and BCAA trial, respectively). This might indicate that an increased supply of BCAA has a sparing effect on muscle glycogen degradation during exercise.</p>
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  • Dobrowolski, Piotr, et al. (författare)
  • Can 2-oxoglutarate prevent changes in bone evoked by omeprazole?
  • 2013
  • Ingår i: Nutrition. - Elsevier. - 1873-1244. ; 29:3, s. 556-561
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: Proton-pump inhibitors, such as omeprazole, are widely used in the prevention and treatment of gastroesophageal diseases. However, an association between proton-pump inhibitors and the increased risk of bone fractures has been observed, especially in patients treated for extended periods. Conversely, 2-oxoglutarate, a precursor of hydroxyproline, the most abundant amino acid in bone collagen, counteracts the bone loss. The aim of the present study was to elucidate the influence of omeprazole on bone and investigate whether dietary 2-oxoglutarate supplementation could prevent the effects of omeprazole. Methods: Eighteen male Sprague-Dawley rats were used. Rats received omeprazole in the diet and 2-oxoglutarate in the drinking water. Body and organ weights and serum concentrations of cholecystokinin and gastrin were measured. The femurs, tibias, and calvarias were collected. Histomorphometric analysis of bone and cartilage tissues was conducted. Bone densitometric and peripheral quantitative computed tomographic analyses of the femur and tibia were performed. Results: Omeprazole decreased the femur and tibia weights, the mechanical properties of the femur, the volumetric bone density and content, the trabecular and cortical bone mineral content, the total, trabecular, and cortical bone areas, the mean cortical thickness, and the periosteal circumference of the femur. Omeprazole had a minor effect on the examined bone morphology and exerted negligible effects on the cartilage. 2-Oxoglutarate lowered the gastrin concentration. Conclusions: Omeprazole treatment exerts its effects mostly on bone mineralization and cancellous bone, adversely affecting bone properties. This adverse effect of omeprazole was not markedly abolished by 2-oxoglutaric acid, which acted as an anti-hypergastrinemic agent. (C) 2013 Elsevier Inc. All rights reserved.
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