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Träfflista för sökning "L773:9780979806452 ;pers:(Wiklund Martin)"

Sökning: L773:9780979806452 > Wiklund Martin

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1.
  • Christakou, Athanasia E., et al. (författare)
  • Characterization of natural killer cells' cytotoxic heterogeneity using an array of sono-cages
  • 2012
  • Ingår i: Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. - : Chemical and Biological Microsystems Society. - 9780979806452 ; , s. 1555-1557
  • Konferensbidrag (refereegranskat)abstract
    • Using a multi-well device as an array of sono-cages for single cell analysis, we quantify for the first time the heterogeneity of natural killer (NK) cells' cytotoxic response against cancer cells. We report a fraction of inactive NK cells within the tested population (36%), as well as the existence of few 'serial killers' that eliminate up to six targets during 4 hours. We also characterize the multi-well acoustic device in terms of trapping efficiency at different actuation voltages, using adherent and non-adherent cell lines. We show that the acoustic forces applied on the cells can be compared to forces of biological processes (i.e. cell adherence).
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2.
  • Ohlin, Mathias, et al. (författare)
  • Analysis of trapping and streaming in an ultrasoundactuated multi-well microplate for single-cell studies
  • 2012
  • Ingår i: Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. - : Chemical and Biological Microsystems Society. - 9780979806452 ; , s. 497-499
  • Konferensbidrag (refereegranskat)abstract
    • The dynamics of the acoustic streaming and the acoustic positioning performance in an ultrasound-actuated multiwell microplate are investigated by two different ultrasonic frequency actuation schemes: Frequency-modulation and single- frequency actuation. Our results show a significant decrease in size of the field of view when using frequencymodulation compared to single-frequency actuation, which can be used for improving the scanning time for 3D highresolution confocal microscopy by almost one order of magnitude. Furthermore, in the ultrasound-actuated multi-well microplate the high-voltage acoustic streaming show a complex time and temperature dependence and could gain stability by the use of temperature control.
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  • Resultat 1-2 av 2
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konferensbidrag (2)
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refereegranskat (2)
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Wiklund, Martin (2)Ta bort avgränsningen
Frisk, Thomas (2)
Önfelt, Björn (2)
Christakou, Athanasi ... (2)
Ohlin, Mathias (2)
Kadri, N (1)
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Kungliga Tekniska Högskolan (2)
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Engelska (2)
Forskningsämne (UKÄ/SCB)
Naturvetenskap (2)
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2012 (2)

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