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Träfflista för sökning "L773:9780979806452 ;srt2:(2012);pers:(Holm Stefan H.)"

Sökning: L773:9780979806452 > (2012) > Holm Stefan H.

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1.
  • Ghasemi, Masoomeh, et al. (författare)
  • Separation of deformable hydrogel microparticles in deterministic lateral displacement devices
  • 2012
  • Ingår i: Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. - 9780979806452 ; , s. 1672-1674
  • Konferensbidrag (refereegranskat)abstract
    • To better understand how deformable and non-spherical particles behave in sorting devices based on deterministic lateral displacement we generate models of biological particles with tunable size, shape and mechanical properties using stop-flow lithography and we explore how these parameters play a role in our separation devices. Hollow and solid cylinders are compared with respect to their deformability and their overall behavior in the device. Future work will expand the approach to a range of particle shapes and to particles with varied hydrogel composition to independently control the mechanical properties of the material.
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2.
  • Holm, Stefan H., et al. (författare)
  • A high-throughput deterministic lateral displacement device for rapid and sensitive field-diagnosis of sleeping sickness
  • 2012
  • Ingår i: Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. - 9780979806452 ; , s. 530-532
  • Konferensbidrag (refereegranskat)abstract
    • We present a simple and rapid microfluidic device capable of extracting and concentrating the parasite causing the fatal disease sleeping sickness (SS) from blood. The device is based on deterministic lateral displacement (DLD) and constructed with a single inlet with flow induced by an ordinary syringe. The simplicity is crucial as the device is intended for use in the resource depraved areas where the disease is endemic. With only one inlet an intricate design with multiple depths has been utilized to create a cell free stream from the blood plasma into which the parasites are forced and subsequently collected in a detection region. In order to maximize the sample volume up to 10 device layers were stacked on top of each other which resulted in a throughput of ∼10 μL/min. This allowed for an approximate time per test of below 15 min.
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  • Resultat 1-2 av 2
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konferensbidrag (2)
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refereegranskat (2)
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Beech, Jason P. (2)
Tegenfeldt, Jonas O. (2)
Holm, Stefan H. (2)Ta bort avgränsningen
Barrett, Michael P. (1)
Ghasemi, Masoomeh (1)
Björnmalm, Mattias (1)
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Lunds universitet (2)
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Engelska (2)
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Medicin och hälsovetenskap (1)
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2012 (2)Ta bort avgränsningen

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