Chemical Analysis of Single Cells

• In this Review, we provide an overview of methods developed for chemical analysis of single cells over the last two years. Many biological systems contain an ensemble of cells with heterogeneous chemistry; therefore, it is important to analyze them on an individual basis in order to elucidate the role each cell plays in the function of these systems. In clinical diagnostics, the development of extremely sensitive measurements, down to single cells, may provide the best ability for diagnoses. Single cell analysis has, in fact, been present for quite some time. Investigators in life sciences consider the cell as the unit of life and so the pursuit to quantify, image, and modulate the cell has been ongoing for decades.

Ämnesord

NATURVETENSKAP  -- Kemi -- Analytisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Analytical Chemistry (hsv//eng)

Nyckelord

scanning electrochemical microscopy

ion mass-spectrometry

in-vivo

droplet microfluidics

living cells

multifunctional pipette

neuroendocrine cells

fluorescent protein

sample preparation

reactive

oxygen

ion mass-spectrometry

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