Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "LAR1:gu ;pers:(Skoog Ingmar 1954);pers:(Östling Svante 1953);mspu:(article)"

Sökning: LAR1:gu > Skoog Ingmar 1954 > Östling Svante 1953 > Tidskriftsartikel

  • Resultat 1-10 av 62
Sortera/gruppera träfflistan
  • Billstedt, Eva, 1961-, et al. (författare)
  • Secular changes in personality: study on 75-year-olds examined in 1976-1977 and 2005-2006.
  • 2013
  • Ingår i: International Journal of Geriatric Psychiatry. - 0885-6230 .- 1099-1166. ; 28:3, s. 298-304
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: In order to study secular changes in personality factors neuroticism and extroversion, representative population samples of non-demented 75-year-olds underwent psychiatric examinations in 1976-1977 (total n = 223, 138 women, 85 men) and 2005-2006 (total n = 556, 322 women and 234 men). METHODS: Eysenck Personality Inventory was used at both occasions. Demographic factors (educational level, marital status, having children) were registered. RESULTS: Seventy-five-year-olds examined in 2005-2006 had higher values on extroversion and lower values on the Lie scale compared with those examined in 1976-1977. Neuroticism did not differ between the two birth cohorts. Neuroticism scores were higher in women than in men both in 1976-1977 and 2005-2006, and Lie score was higher in women than in men in 2005-2006. CONCLUSIONS: Our findings suggest that present cohorts of 75-year-olds are more extroverted and less prone to respond in a socially desirable manner than those born three decades earlier. Neuroticism levels remained unchanged, suggesting this trait may be less influenced by environmental factors than the other traits studied.
  • Bjerke, Maria, 1977-, et al. (författare)
  • Cerebrospinal Fluid Fatty Acid-Binding Protein 3 is Related to Dementia Development in a Population-Based Sample of Older Adult Women Followed for 8 Years.
  • 2016
  • Ingår i: Journal of Alzheimer's disease : JAD. - 1875-8908. ; 49:3, s. 733-741
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Increased fatty acid-binding protein 3 (FABP-3) levels have been reported in neurodegenerative diseases, including Alzheimer's disease (AD). Cerebrospinal fluid (CSF) FABP-3 has therefore been proposed as a putative marker for dementia. Population-based studies examining whether CSF FABP-3 predicts later development of dementia are lacking. OBJECTIVE: The aim of this study was to examine CSF levels of FABP-3 in relation to later development of dementia in elderly women and in relation to Aβ42, T-tau, P-tau181, and CSF: serum albumin ratio. METHODS: 86 non-demented women aged 70-84 years who participated in the Prospective Population Study of Women in Gothenburg, Sweden took part in a lumbar puncture in 1992-93. CSF-FABP-3, Aβ42, T-tau, P-tau181, and the CSF: serum albumin ratio were measured at baseline. Participants were examined with a neuropsychiatric exam at baseline and at follow-up in 2000. Dementia was diagnosed in accordance with DSM-III-R criteria. RESULTS: Between 1992 and 2000, 8 women developed dementia (4 AD, 3 vascular dementia, 1 mixed vascular dementia and AD). Higher levels of CSF-FABP-3 at baseline were related to development of dementia (OR 1.36 CI [1.05-1.76] p = 0.022) and the subtype AD (OR 1.38 CI [1.06-1.82), p = 0.019) during follow-up. FABP-3 correlated with CSF T-tau (r = 0.88, p <  0.001), P-tau181 (r = 0.619, p <  0.001), and CSF:serum albumin ratio (r = 0.233, p = 0.031), but not with Aβ42 (r = -0.08, p = 0.444)Conclusion: CSF FABP-3 may be an early marker for later development of dementia, probably related to neuronal degeneration, but independent of Aβ metabolism.
  • Bäckman, Kristoffer, 1979-, et al. (författare)
  • 37 years of body mass index and dementia: observations from the prospective population study of women in Gothenburg, Sweden.
  • 2012
  • Ingår i: Journal of Alzheimer's disease : JAD. - 1875-8908. ; 28:1, s. 163-71
  • Tidskriftsartikel (refereegranskat)abstract
    • Level of adiposity is linked to dementia in epidemiological studies. Overweight and obesity in mid- and late-life may increase risk for dementia, whereas decline in body weight or body mass index (BMI) and underweight in years preceding and at the time of a dementia diagnosis may also relate to dementia. Longitudinal studies with sufficient follow-up are necessary to estimate trajectories that allow better understanding of the relationship between adiposity indices and dementia over the life course. We evaluated the natural history of BMI in relationship to clinical dementia over 37 years in the Prospective Population Study of Women (PPSW) in Sweden. PPSW is a systematic sample of 1462 women born 1908, 1914, 1918, 1922, and 1930 and aged 38-60 years at baseline. Examinations occurred in 1968, 1974, 1980, 1992, 2000, and 2005. Statistical analyses were conducted using mixed effects regression models. Trajectories of BMI over 37 years as a function of age differed between women who did versus did not develop dementia. Women developing dementia evidenced a lesser increase in BMI from age 38 to 70 years. After age 70, the BMI slope decreased similarly (no "accelerated decline") irrespective of dementia status. A lower BMI before and during dementia onset was observed. Women with similar BMI at mid-life exhibited a different pattern of BMI change as they approached late-life that was related to dementia onset. BMI may be a potential marker of dementia-related neuropathologies in the brain. Dementia is related to a common risk factor, BMI, from mid-to late-life.
  • Börjesson-Hanson, Anne, 1959-, et al. (författare)
  • One-Month Prevalence of Mental Disorders in a Population Sample of 95-Year Olds.
  • 2011
  • Ingår i: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. - 1545-7214. ; 19:3, s. 284-91
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE:: To determine the 1-month prevalence of mental disorders among 95-year olds. DESIGN:: Cross-sectional population sample of 95-year olds. SETTING:: All 95-year olds born in the period 1901-1903 living in Gothenburg, Sweden, were invited. Elderly living in both community settings and nursing homes were included. PARTICIPANTS:: In total, 338 95-year olds (response rate: 65%) were examined (263 women, 75 men). MEASUREMENTS:: All participants were examined by psychiatrists using the Comprehensive Psychopathological Rating Scale and cognitive tests. Mental disorders were classified according to Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised criteria. RESULTS:: Two-third of all 95-year olds had a mental disorder. In the total sample of 95-year olds, the 1-month prevalence was 52% for dementia, 8% for depression, 4% for anxiety, and 3% for psychotic disorders. Almost one-third (29%) of the nondemented 95-year olds fulfilled criteria for a psychiatric disorder: 17% had depression, 9% anxiety, and 7% psychotic disorder. CONCLUSIONS:: The combined prevalence of mental disorders was high among 95-year olds, even after excluding dementia. These findings emphasize the importance of research, care, and detection of psychiatric problems in this age group.
  • Falk, Hanna, 1977-, et al. (författare)
  • Functional disability and ability 75-year-olds: a comparison of two Swedish cohorts born 30 years apart
  • 2014
  • Ingår i: Age and Ageing. - 0002-0729 .- 1468-2834. ; 43:5, s. 636-641
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To compare the level of functional disability and involvement in leisure activities between two birth cohorts of Swedish 75-year-olds examined in 1976-77 and 2005-06. Design :Cohort comparison. Setting and Participants: Representative data from the general population in Gothenburg, Sweden, examined at age 75 in 1976–77 (N= 744), and in 2005–06 (N= 731) with comprehensive somatic and psychiatric examinations. Measurements: Activities of daily living (ADL); Instrumental activities of daily living (IADL); a battery of self-report measures, including involvement in leisure activities, satisfaction with home environment, social networks, and self-rated health. Results: Functional disability in ADL decreased between the cohorts (13.9% vs. 5.6%, p<.001). Functional disability in IADL also decreased between the cohorts (33.4% vs. 13.0%, p<.001). Combining ADL and IADL resulted in an overall decreased dependency, with the largest decrease seen in women (42.3% vs. 15.1%, p<.001). Involvement in leisure activities increased between the cohorts. For example, the proportion going on international and domestic holiday travels increased (44.6% vs. 72.8%, p<.001), and the proportion who independently drove their own car also increased (10.0% vs. 53.0%, p<.001). Conclusion: Later born cohorts of 75-year-olds are less dependent in activities of daily living and more engaged in leisure activities compared to earlier cohorts. Later born cohorts of 75-year-olds are thus better equipped to maintain a non-age related identity compared to earlier cohorts. Our findings might serve as a reason to adopt a more positive view to aging in a world with an increasing number of older people.
  • Fredén Klenfeldt, Isak, 1980-, et al. (författare)
  • Prevalence of Obsessive-compulsive Disorder in Relation to Depression and Cognition in an Elderly Population
  • 2014
  • Ingår i: The American journal of geriatric psychiatry. - 1064-7481. ; 22:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives We examined the 1-month prevalence of obsessive-compulsive disorder (OCD) and obsessive-compulsive symptoms (OCS) not fulfilling OCD criteria in relation to sex, age, social and mental function, comorbid depression, and cognitive functioning in an elderly nondemented population. Settings and Participants Population-based sample (N = 900), stratified into two age groups: 70-year-olds (335 women and 224 men) and those aged 78 and above (341 women). Measurements Semi-structured interviews. Psychiatric symptoms were assessed with the Comprehensive Psychopathological Rating Scale and Mini-International Neuropsychiatric Interview, mental and social function with the GAF-scale, memory function with the Word Recall Task and general cognition with MMSE. OCD and Depression were diagnosed according to DSM-IV. Results The one-month prevalence of OCD was 2.9%; a further 21% had OCS. Among 70-year-olds, the prevalence of OCD was 1.3% in men and 4.5% in women. Depression was more common among those with OCD (34.6%) than among those with (12.7%) and without (8.0%) OCS. GAF-score was lower among those with OCD (74.8) and OCS (82.9) compared with individuals without obsessions and compulsions (88.2). The association between OCD and GAF-score remained after adjustment for age, sex, and depression. The OCD subgroup with checking behavior had more memory and concentration problems and did worse on Word Recall Task than other groups in our sample. Conclusions We found that OCD and OCS are common among the elderly. Both conditions are related to depression and poorer mental and social functioning. Physicians who meet elderly patients need to be aware of OCD as it is potentially treatable.
  • Gislason, Thorsteinn, et al. (författare)
  • Effect of diagnostic criteria on the prevalence of frontotemporal dementia in the elderly
  • 2015
  • Ingår i: Alzheimer's & Dementia. - 1552-5260 .- 1552-5279. ; 11:4
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Frontotemporal dementia (FTD) is believed to be rare in the elderly, and the influence of different criteria on the prevalence of FTD is unclear. METHODS: Population-based samples of 70- to 95-year-olds (n = 2462) in Gothenburg, Sweden, underwent neuropsychiatric examinations. Behavioral variant FTD (bvFTD) was diagnosed according to the International Behavioural Variant FTD Criteria Consortium (FTDC), the Frontotemporal Lobe Degeneration Consensus criteria, and the Lund-Manchester Research Criteria. A subset (n = 1074) underwent computerized tomography (CT) of the brain. RESULTS: The prevalence of bvFTD varied between 0.2% and 0.5% at age 70 to 79 years, between 2.5% and 3.6% at age 80 to 89 years, and between 1.7% and 2.2% at age 90 to 95 years. The agreement between different criteria was low to moderate (κ = 0.20-0.42). Among those with bvFTD according to FTDC, 93.3% had frontal and/or temporal lobar atrophy on CT, compared with 12.6% of those without bvFTD (P < .001). CONCLUSIONS: The prevalence of bvFTD was higher than expected in this population. To a large extent, different criteria captured different individuals.
  • Gudmundsson, Pia, 1978-, et al. (författare)
  • Longitudinal associations between physical activity and depression scores in Swedish women followed 32 years
  • 2015
  • Ingår i: Acta Psychiatrica Scandinavica. - 0001-690X .- 1600-0447. ; 132:6
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: Physical activity is negatively associated with depressive symptoms. However, few studies consider dynamic associations of changes in physical activity and reciprocal relationships. This study aimed to perform comprehensive evaluations of relationships between physical activity and depression scores in women followed from mid- to late life. Method: The Prospective Population Study of Women in Gothenburg, Sweden, provided repeated measures of self-reported physical activity and depressive symptoms between 1974 and 2005 (baseline N = 676, 84.5% response rate). Depressive symptoms were assessed using the Montgomery–Åsberg Depression Rating Scale, and physical activity was evaluated by the Saltin–Grimby Physical Activity Level Scale. Latent growth curve analyses were used to evaluate associations of change, and cross-lagged models were used to study the reciprocal relationship between physical activity and depression scores. Results: At baseline, lower levels of physical activity were related to higher depression scores. Individuals with decreasing physical activity over time evidenced higher depression scores at 32-year follow-up. Higher average baseline depression score was related to declining levels of physical activity at subsequent examinations. Conclusion: Reduced physical activity may be a long-term consequence of depression. It is important to address individual changes in physical activity and not merely absolute levels of physical activity in relationship to depression.
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 62
fritt online (10)
Typ av publikation
Typ av innehåll
refereegranskat (61)
övrigt vetenskapligt (1)
Waern, Margda, 1955- ... (39)
Gustafson, Deborah, ... (21)
Blennow, Kaj, 1958-, (13)
Zetterberg, Henrik, ... (11)
visa fler...
Marlow, Thomas, (8)
Lissner, Lauren, 195 ... (6)
Joas, Erik, 1983-, (6)
Falk, Hanna, 1977-, (5)
Björkelund, Cecilia, ... (5)
Karlsson, Björn, (4)
Bengtsson, Calle, 19 ... (4)
Johansson, Boo (3)
Sundh, Valter, 1950- ... (3)
Mehlig, Kirsten, 196 ... (3)
Larsson, L (2)
Rosengren, Lars, 195 ... (2)
Hallstrom, T, (2)
Steen, Bertil, 1938- ... (2)
Wikkelsö, Carsten, 1 ... (2)
Hällström, Tore, 193 ... (2)
Sjögren, Magnus, (2)
Thorvaldsson, Valgei ... (2)
Ostling, S. (2)
Billstedt, Eva, 1961 ... (2)
Waern, M (1)
Johansson, L (1)
Jacobsson, L. (1)
Schütze, Madlen (1)
Larsson, A, (1)
Carlsson, Lena M S, ... (1)
Lapidus, L (1)
Bengtsson, C (1)
Fichter, Manfred (1)
Thelle, Dag, 1942-, (1)
Eriksson, Elias, 195 ... (1)
Zandi, Peter P (1)
Runeson, B, (1)
Hansson, Oskar (1)
Jensen, Christer, (1)
Lindwall, Magnus, 19 ... (1)
Wiberg, P., (1)
Mielke, M. (1)
Beckman, Nils, (1)
Wancata, Johannes (1)
Landahl, Sten (1)
Beskow, J. (1)
Duberstein, P. (1)
Duberstein, Paul (1)
visa färre...
Göteborgs universitet (62)
Karolinska Institutet (2)
Engelska (62)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (61)
Samhällsvetenskap (3)


pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy