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Träfflista för sökning "LAR1:gu ;pers:(Wallin Anders 1950);pers:(Blennow Kaj 1958);pers:(Rüetschi Ulla 1962)"

Sökning: LAR1:gu > Wallin Anders 1950 > Blennow Kaj 1958 > Rüetschi Ulla 1962

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1.
  • Folkesson Hansson, Sara, 1976-, et al. (författare)
  • Cystatin C in cerebrospinal fluid and multiple sclerosis
  • 2007
  • Ingår i: Ann Neurol. ; 62:2, s. 193-196
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: A recent study using surface-enhanced laser desorption/ionization time-of-flight analysis of cerebrospinal fluid identified a 12.5kDa truncated isoform of cystatin C (CysC) as a specific biomarker for multiple sclerosis (MS). METHODS: Surface-enhanced laser desorption/ionization time-of-flight analysis of cerebrospinal fluid samples from 43 MS patients and 46 healthy control subjects. RESULTS: Full-length CysC (13.4kDa) concentration was similar in MS and control samples. The 12.5kDa CysC protein was produced from full-length CysC by N-terminal cleavage during storage at -20 degrees C. INTERPRETATION: The 12.5kDa CysC isoform is a storage-related artifact and is not useful as a diagnostic marker for MS. Ann Neurol 2007;62:193-196.
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2.
  • Hansson, Sarah, 1976-, et al. (författare)
  • Cystatin C in cerebrospinal fluid and multiple sclerosis.
  • 2007
  • Ingår i: Annals of neurology. - 0364-5134. ; 62:2, s. 193-6205
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: A recent study using surface-enhanced laser desorption/ionization time-of-flight analysis of cerebrospinal fluid identified a 12.5 kDa truncated isoform of cystatin C (CysC) as a specific biomarker for multiple sclerosis (MS). METHODS: Surface-enhanced laser desorption/ionization time-of-flight analysis of cerebrospinal fluid samples from 43 MS patients and 46 healthy control subjects. RESULTS: Full-length CysC (13.4 kDa) concentration was similar in MS and control samples. The 12.5 kDa CysC protein was produced from full-length CysC by N-terminal cleavage during storage at -20 degrees C. INTERPRETATION: The 12.5 kDa CysC isoform is a storage-related artifact and is not useful as a diagnostic marker for MS.
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