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- Cherkasov, A. R., et al.
(författare)
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Correlation analysis in the chemistry of free radicals
- 2001
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Ingår i: Uspehi himii. - 0042-1308. ; 70:1, s. 3-27
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Forskningsöversikt (refereegranskat)abstract
- Published data available by now on the use of correlation analysis in the free-radical chemistry are discussed systematically. The scales of <> sigma -constants of substituents proposed previously are analysed. It is shown that none of them is suitable as a general scale because almost in all cases, it is impossible to separate correctly the proper radical and polar contributions to the overall effect of substituents. A new approach to the quantitative estimation of the relationship between the structure and reactivity of molecules in free-radical processes is proposed and called r(-2)-analysis.
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- Ivanova, L N, et al.
(författare)
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[Vasopressin : the ontogeny of antidiuretic action at the cellular level].
- 1989
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Ingår i: Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova. - 0015-329X. ; 75:7, s. 970-9
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Tidskriftsartikel (refereegranskat)abstract
- The data on the development of molecular mechanism of the antidiuretic effect of vasopressin and the molecular structure of the AVP receptor, cytosolic cAMP-dependent protein-kinases and renal response to AVP, are discussed. The experiments were performed in normal rats and mice, nephrogenic diabetes insipidus mutants and rats treated with cortisol in early postnatal period. The development of the kidney sensitivity to AVP seems to be closely connected with the development of the molecular structure of the AVP receptor, age-related increase of the AVP-activated adenylate cyclase, and the maturation of cAMP-dependent protein kinases.
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