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  • Adolfsson, ET, et al. (författare)
  • Type 2 diabetic patients' experiences of two different educational approaches : A qualitative study
  • 2008
  • Ingår i: International Journal of Nursing Studies. - 0020-7489 .- 1873-491X. ; 7:45, s. 986-994
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: The aim of the current study was to explore patients' experiences of participating in an empowerment group education programme or receiving individual counselling. Method: In total, 28 patients from seven primary care centres were interviewed. Of these, 14 had received individual counselling and the remaining 14 had also participated in 4-5 empowerment group sessions. The semi-structured interviews were tape-recorded, transcribed verbatim and analysed using qualitative content analysis. Findings: Three main categories crystallized from the interviews: (I) relationships, (II) learning and (III) controlling the disease. The relationships in the individual counselling seemed vertical, characterized by one-way communication with care providers acting as superiors and patients as subordinates. The relationships in the empowerment group appeared to be horizontal, characterized by trust and mutual communication. Those who had received individual counselling talked about learning by compliance-care providers acted as superiors, giving advice they expected the patients to follow. In the empowerment groups the patients talked more about participatory learning, whereby the facilitators and patients shared their knowledge and experiences. Controlling the disease could be labelled external in individual counselling, which made it difficult for patients to take responsibility for and control of their diabetes self-care. On the contrary, the patients in the empowerment group achieved the insight that diabetes is a serious disease but can be influenced, which contributed to their experience of self-control. Conclusions: The current study indicates that vertical relationships, learning by compliance and external control seem to limit patients' ability to take responsibility for their disease, while horizontal relationships, participatory learning and self-control may contribute to strengthening patients' ability to influence and be actively involved in their own care.
  • Agmo Hernández, Víctor, et al. (författare)
  • Enhanced interpretation of adsorption data generated by liquid chromatography and by modern biosensors
  • 2013
  • Ingår i: Journal of Chromatography A. - 0021-9673. ; 1317, s. 22-31
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study we demonstrate the importance of proper data processing in adsorption isotherm estimations. This was done by investigating and reprocessing data from five cases on two closely related platforms: liquid chromatography (LC) and biosensors. The previously acquired adsorption data were reevaluated and reprocessed using a three-step numerical procedure: (i) preprocessing of adsorption data, (ii) adsorption data analysis and (iii) final rival model fit. For each case, we will discuss what we really measure and what additional information can be obtained by numerical processing of the data. These cases clearly demonstrate that numerical processing of LC and biosensor data can be used to gain deeper understanding of molecular interactions with adsorption media. This is important because adsorption data, especially from biosensors, is often processed using old and simplified methods. (C) 2013 Elsevier B.V. All rights reserved.
  • Alavian-Ghavanini, Ali, et al. (författare)
  • Prenatal Bisphenol A Exposure is Linked to Epigenetic Changes in Glutamate Receptor Subunit Gene Grin2b in Female Rats and Humans
  • 2018
  • Ingår i: Scientific Reports. - Nature Publishing Group. - 2045-2322. ; 8
  • Tidskriftsartikel (refereegranskat)abstract
    • Bisphenol A (BPA) exposure has been linked to neurodevelopmental disorders and to effects on epigenetic regulation, such as DNA methylation, at genes involved in brain function. High doses of BPA have been shown to change expression and regulation of one such gene, Grin2b, in mice. Yet, if such changes occur at relevant doses in animals and humans has not been addressed. We investigated if low-dose developmental BPA exposure affects DNA methylation and expression of Grin2b in brains of adult rats. Furthermore, we assessed associations between prenatal BPA exposure and Grin2b methylation in 7-year old children. We found that Grin2b mRNA expression was increased and DNA methylation decreased in female, but not in male rats. In humans, prenatal BPA exposure was associated with increased methylation levels in girls. Additionally, Iow APGAR scores, a predictor for increased risk for neurodevelopmental diseases, were associated with higher Grin2b methylation levels in girls. Thus, we could link developmental BPA exposure and Iow APGAR scores to changes in the epigenetic regulation of Grin2b, a gene important for neuronal function, in a sexual dimorphic fashion. Discrepancies in exact locations and directions of the DNA methylation change might reflect differences between species, analysed tissues, exposure level and/or timing.
  • Alfredsson, Stefan, 1976-, et al. (författare)
  • A 4G Link Level Emulator for Transport Protocol Evaluation
  • 2004
  • Ingår i: Proceedings of The Second Swedish National Computer Networking Workshop (SNCNW). ; s. 19-23
  • Konferensbidrag (refereegranskat)abstract
    • This paper presents a wireless link and networkemulator, based upon the "Wireless IP" 4G system proposalfrom Uppsala University and partners. In wireless fading down-links (base to terminals) link-level frames are scheduled andthe transmission is adapted on a fast time scale. With fastlink adaptation and fast link level retransmission, the fading properties of wireless links can to a large extent be counteractedat the physical and link layers. A purpose of the emulatoris to investigate the resulting interaction with transport layer protocols. The emulator is built on Internet technologies, andis installed as a gateway between communicating hosts. The paper gives an overview of the emulator design, and presentspreliminary experiments with three different TCP variants. The results illustrate the functionality of the emulator by showing theeffect of changing link layer parameters on the different TCP variants.
  • Allvin, Michael, et al. (författare)
  • Den utbredda flexibiliteten ett försök att beräkna förekomsten av lågreglerade arbetsvillkor
  • 2012
  • Ingår i: Arbetsmarknad & Arbetsliv. - Stockholm : Arbetsmarknadsstyrelsen. - 1400-9692. ; 18:1, s. 9-24
  • Tidskriftsartikel (refereegranskat)abstract
    • Nästan 30 år efter det att begreppet flexibilitet i arbetslivet kom i bruk råder det fortfarande stor osäkerhet om vad begreppet innebär och hur vanligt det egentligen är. I artikeln diskuteras flexibilitet utifrån en representativ studie av den svenska arbetskraften. I studien konstateras att både traditionellt organiserade och helt fria arbeten är relativt ovanliga. Däremot är flexibla arbetsvillkor desto mer vanligt förekommande och spridda i varierande grad bland den svenska arbetskraften.
  • Allvin, Michael, et al. (författare)
  • "Självständiga lärosäten": Om de förändrade villkoren för högre utbildning och universitetens normalisering
  • 2011
  • Ingår i: Arbetsmarknad & Arbetsliv. - Karlstad : Karlstads universitet. - 1400-9692. ; 17:2, s. 59-73
  • Tidskriftsartikel (refereegranskat)abstract
    • När den högre utbildningen avregleras får universitet  och högskolor själva bestämma hur de ska organisera sin verksamhet. Det sker även i den övriga västvärlden, liksom i den övriga svenska offentliga sektorn. Frågan är dock vad ett sådant självbestämmande egentligen är värt. Avregleringen lämnar nämligen lärosätena att konkurrera med varandra på en allt snävare och alltmer standardiserad spelplan, vilket i sin tur tvingar dem till långtgående rationaliseringar och prioriteringar.
  • Anclair, Malin, et al. (författare)
  • Parental fears following their child's brain tumor diagnosis and treatment.
  • 2009
  • Ingår i: Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. - 1043-4542. ; 26:2, s. 68-74
  • Tidskriftsartikel (refereegranskat)abstract
    • The objective of this study is to portray the illness-related threats experienced by parents of children after the diagnosis of central nervous system (CNS) tumor. Parents were asked to rate the extent to which they experienced a set of specific fears related to their child's brain tumor and its treatment. Outcomes for parents of CNS tumor patients (n = 82) were compared with those of reference parents of patients treated for acute lymphoblastic leukemia (n = 208). The fears about an illness recurrence and the late effects of treatment were most prominent among parents of CNS tumor patients. For 7 out of 11 kinds of fear, parents of CNS tumor patients expressed a stronger fear than the reference group. More than a quarter of the parents of children treated for CNS tumors feared a complete decline of the child. Parents of CNS tumor patients experience relatively heightened cancer related fears in several domains. The fear of devastating consequences felt by one fourth of parents signals the need of individualized psychological support and information at diagnosis and follow-up to facilitate parental coping with the posttreatment situation.
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