| 1. |
- Andersson, Gerhard, et al.
(författare)
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Therapeutic alliance in guided internet-delivered cognitive behavioural treatment of depression, generalized anxiety disorder and social anxiety disorder
- 2012
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Ingår i: Behaviour Research and Therapy. - : Elsevier. - 0005-7967 .- 1873-622X. ; 50:9, s. 544-550
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Tidskriftsartikel (refereegranskat)abstract
- Guided internet-delivered cognitive behaviour therapy (ICBT) has been found to be effective in several controlled trials, but the mechanisms of change are largely unknown. Therapeutic alliance is a factor that has been studied in many psychotherapy trials, but the role of therapeutic alliance in ICBT is less well known. The present study investigated early alliance ratings in three separate samples. Participants from one sample of depressed individuals (N = 49), one sample of individuals with generalized anxiety disorder (N = 35), and one sample with social anxiety disorder (N = 90) completed the Working Alliance Inventory (WAI) modified for ICBT early in the treatment (weeks 3-4) when they took part in guided ICBT for their conditions. Results showed that alliance ratings were high in all three samples and that the WAI including the subscales of Task, Goal and Bond had high internal consistencies. Overall, correlations between the WAI and residualized change scores on the primary outcome measures were small and not statistically significant. We conclude that even if alliance ratings are in line with face-to-face studies, therapeutic alliance as measured by the WAI is probably less important in ICBT than in regular face-to-face psychotherapy.
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| 2. |
- Costache, Madalina Elena, et al.
(författare)
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Higher- and lower-order personality traits and cluster subtypes in social anxiety disorder
- 2020
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Ingår i: PLOS ONE. - : PUBLIC LIBRARY SCIENCE. - 1932-6203. ; 15:4
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Tidskriftsartikel (refereegranskat)abstract
- Social anxiety disorder (SAD) can come in different forms, presenting problems for diagnostic classification. Here, we examined personality traits in a large sample of patients (N = 265) diagnosed with SAD in comparison to healthy controls (N = 164) by use of the Revised NEO Personality Inventory (NEO-PI-R) and Karolinska Scales of Personality (KSP). In addition, we identified subtypes of SAD based on cluster analysis of the NEO-PI-R Big Five personality dimensions. Significant group differences in personality traits between patients and controls were noted on all Big Five dimensions except agreeableness. Group differences were further noted on most lower-order facets of NEO-PI-R, and nearly all KSP variables. A logistic regression analysis showed, however, that only neuroticism and extraversion remained significant independent predictors of patient/control group when controlling for the effects of the other Big Five dimensions. Also, only neuroticism and extraversion yielded large effect sizes when SAD patients were compared to Swedish normative data for the NEO-PI-R. A two-step cluster analysis resulted in three separate clusters labelled Prototypical (33%), Introvert-Conscientious (29%), and Instable-Open (38%) SAD. Individuals in the Prototypical cluster deviated most on the Big Five dimensions and they were at the most severe end in profile analyses of social anxiety, self-rated fear during public speaking, trait anxiety, and anxiety-related KSP variables. While additional studies are needed to determine if personality subtypes in SAD differ in etiological and treatment-related factors, the present results demonstrate considerable personality heterogeneity in socially anxious individuals, further underscoring that SAD is a multidimensional disorder.
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| 3. |
- Damas, Giane Benvinda, et al.
(författare)
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Carbon dioxide reduction mechanism on Ru-based electrocatalysts [Ru(bpy)(2)(CO)(2)](2+) : insights from first-principles theory
- 2021
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Ingår i: Sustainable Energy & Fuels. - : Royal Society of Chemistry. - 2398-4902. ; 5:23, s. 6066-6076
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Tidskriftsartikel (refereegranskat)abstract
- Solar fuel production through the so-called artificial photosynthesis has attracted a great deal of attention to the development of a new world energy matrix that is renewable and environmentally friendly. This process is characterized by light absorption with enough photon energy to generate conduction electrons, which drive the carbon dioxide reduction to produce organic fuels. It is also common to couple Ru-complex electrocatalysts to form a more efficient and selective hybrid system for this application. In this work, we have undertaken a thorough investigation of the redox reaction mechanism of Ru-based electrocatalysts by means of density functional theory (DFT) methods under the experimental conditions that have been previously reported. More specifically, we have studied the electrochemistry and catalytic activity of the [Ru(bpy)(2)(CO)(2)](2+) coordination complex. Our theoretical assessment supports the following catalytic cycle: (i) [Ru(bpy)(2)(CO)(2)](2+) is transformed into [Ru(bpy)(2)(CO)](0) upon two-electron reduction and CO release; (ii) [Ru(bpy)(2)(CO)](0) is protonated to form the [Ru(bpy)(2)(CO)H](+) hydride complex; (iii) CO2 is activated by the hydride complex through an electrophilic addition to form the [Ru(bpy)(2)(CO)(OCHO)](+) intermediate; (iv) the resulting formic acid ligand is released in solution; and, finally, (v) the CO ligand is reattached to the complex to recover the initial [Ru(bpy)(2)(CO)(2)](2+) catalyst.
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| 4. |
- Damas, Giane, et al.
(författare)
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Understanding carbon dioxide capture on metal-organic frameworks from first-principles theory : The case of MIL-53(X), with X = Fe3+, Al3+, and Cu2
- 2021
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Ingår i: Journal of Chemical Physics. - : American Institute of Physics (AIP). - 0021-9606 .- 1089-7690. ; 155:2
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Tidskriftsartikel (refereegranskat)abstract
- Metal-organic frameworks (MOFs) constitute a class of three-dimensional porous materials that have shown applicability for carbon dioxide capture at low pressures, which is particularly advantageous in dealing with the well-known environmental problem related to the carbon dioxide emissions into the atmosphere. In this work, the effect of changing the metallic center in the inorganic counterpart of MIL-53 (X), where X = Fe3+, Al3+, and Cu2+, has been assessed over the ability of the porous material to adsorb carbon dioxide by means of first-principles theory. In general, the non-spin polarized computational method has led to adsorption energies in fair agreement with the experimental outcomes, where the carbon dioxide stabilizes at the pore center through long-range interactions via oxygen atoms with the axial hydroxyl groups in the inorganic counterpart. However, spin-polarization effects in connection with the Hubbard corrections, on Fe 3d and Cu 3d states, were needed to properly describe the metal orbital occupancy in the open-shell systems (Fe- and Cu-based MOFs). This methodology gave rise to a coherent high-spin configuration, with five unpaired electrons, for Fe atoms leading to a better agreement with the experimental results. Within the GGA+U level of theory, the binding energy for the Cu-based MOF is found to be E-b = -35.85 kJ/mol, which is within the desirable values for gas capture applications. Moreover, it has been verified that the adsorption energetics is dominated by the gas-framework and internal weak interactions.
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| 5. |
- Furmark, Tomas, et al.
(författare)
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Serotonin synthesis rate and the tryptophan hydroxylase-2: G-703T polymorphism in social anxiety disorder
- 2016
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Ingår i: Journal of Psychopharmacology. - London, United Kingdom : SAGE Publications. - 0269-8811 .- 1461-7285. ; 30:10, s. 1028-1035
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Tidskriftsartikel (refereegranskat)abstract
- It is disputed whether anxiety disorders, like social anxiety disorder, are characterized by serotonin over- or underactivity. Here, we evaluated whether our recent finding of elevated neural serotonin synthesis rate in patients with social anxiety disorder could be reproduced in a separate cohort, and whether allelic variation in the tryptophan hydroxylase-2 (TPH2) G-703T polymorphism relates to differences in serotonin synthesis assessed with positron emission tomography. Eighteen social anxiety disorder patients and six healthy controls were scanned during 60 minutes in a resting state using positron emission tomography and 5-hydroxy-L-[ -C-11]tryptophan, [C-11]5-HTP, a substrate of the second enzymatic step in serotonin synthesis. Parametric images were generated, using the reference Patlak method, and analysed using Statistical Parametric Mapping (SPM8). Blood samples for genotyping of the TPH2 G-703T polymorphism were obtained from 16 social anxiety disorder patients (T carriers: n=5, GG carriers: n=11). A significantly elevated [C-11]5-HTP accumulation rate, indicative of enhanced decarboxylase activity and thereby serotonin synthesis capacity, was detected in social anxiety disorder patients compared with controls in the hippocampus and basal ganglia nuclei and, at a more lenient (uncorrected) statistical threshold, in the amygdala and anterior cingulate cortex. In patients, the serotonin synthesis rate in the amygdala and anterior cingulate cortex was significantly elevated in TPH2 T carriers in comparison with GG homozygotes. Our results support that social anxiety disorder entails an overactive presynaptic serotonergic system that, in turn, seems functionally influenced by the TPH2 G-703T polymorphism in emotionally relevant brain regions.
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| 6. |
- Granstrom, Fredrik, et al.
(författare)
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Economic stress and condescending treatment in childhood and adult self-rated health : results from a population study in Sweden
- 2017
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Ingår i: BMC Public Health. - : BioMed Central. - 1471-2458. ; 17
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Tidskriftsartikel (refereegranskat)abstract
- Background: Even today, 12% of the children in Sweden live in poverty and many children are exposed to adverse experiences, such as being bullied, which may have long-term consequences on public health. This study examined the associations between economic stress and condescending treatment in childhood and self-rated health (SRH) in adulthood. Methods: The study is based on 26,706 persons who responded to a postal survey questionnaire sent to a random sample of men and women aged 25-84 years in 2012 (response rate 53%). The associations between childhood circumstances and adult SRH were analysed by logistic regression, adjusting for sex, age, economic stress in adulthood, condescending treatment in adulthood, socioeconomic status and several other known material, behavioural and psychosocial risk factors. Results: In total, 39% of both men and women reported economic stress in their family during childhood. 36% of the men and 41% of the women indicated that they had been treated in a condescending manner, e.g. in school or at home, during childhood. Both economic stress in childhood and condescending treatment in childhood were strongly associated with adult SRH. The associations attenuated, but were still statistically significant after adjustment for adulthood circumstances and other risk factors. Conclusion: Economic stress in childhood and condescending treatment in childhood were associated with SRH in adulthood, both independently and through adulthood circumstances. The results underline the importance of taking into account both material and psychosocial circumstances over the whole life course when developing public health measures.
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| 7. |
- Granström, Fredrik, et al.
(författare)
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Distinguishing independent and shared effects of material/structural conditions and psychosocial resources on educational inequalities in self-rated health : results from structural equation modelling
- 2021
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Ingår i: Public Health. - : Elsevier. - 0033-3506 .- 1476-5616. ; 196, s. 10-17
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: The aim of this study was to distinguish independent and shared effects of material/structural factors and psychosocial resources in explaining educational inequalities in self-rated health (SRH) by using structural equation modelling. Study design: Cross-sectional survey. Methods: Data were derived from a questionnaire sent to a random sample of the population in five counties in Sweden in 2008. The study population (aged 25–75 years) included 15,099 men and 17,883 women. Exploratory structural equation modelling was used to analyse the pathways from educational level to SRH. Results: The pathway including both material/structural factors (e.g. financial buffer and unemployment) and psychosocial resources (e.g. sense of coherence and social participation) explained about 40% of educational differences in SRH for both men and women. The pathways including only the independent effects of psychosocial resources (14% in men and 20% in women) or material/structural factors (9% and 18%, respectively) explained substantial but smaller proportions of the differences. Conclusions: The major pathway explaining educational inequalities in SRH included both material/structural factors and psychosocial resources. Therefore, to reduce educational inequalities in SRH, interventions need to address both material/structural conditions and psychosocial resources across educational groups.
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| 8. |
- Göransson, Kerstin, 1955-, et al.
(författare)
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Inclusive education in Sweden? A critical analysis
- 2011
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Ingår i: International Journal of Inclusive Education. - : Informa UK Limited. - 1360-3116 .- 1464-5173. ; 15:5, s. 541-555
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Tidskriftsartikel (refereegranskat)abstract
- When it comes to pupils in need of special support and pupils with disabilities, Sweden's compulsory school system is sometimes considered a one-track system. This article analyses and critically discusses current policy and practices at various levels of Sweden's compulsory school system for these pupils. The analysis traces three themes at the national and municipal levels: (1) values and goals; (2) organisation and placement of pupils; and (3) importance of categories in obtaining support. A rather complex picture emerges from this analysis. Several conclusions are made: (1) state policies leave a lot of room for interpretation at the municipal and school levels, and this results in an extensive variation; (2) Swedish state policy is not as inclusive as is often stated; (3) celebration of difference seems to be hard to achieve; (4) learning goals can be a double-edged sword with regard to inclusion; and (5) most pupils appear to enjoy participation in school, and in an international perspective, Swedish classrooms seem to be largely democratic.
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| 9. |
- Hearn, Jeff, 1947-, et al.
(författare)
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Hegemonic masculinity and beyond : 40 years of research in Sweden
- 2012
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Ingår i: Men and Masculinities. - Thousand Oaks, CA : Sage Publications. - 1097-184X .- 1552-6828. ; 15:1, s. 31-55
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Tidskriftsartikel (refereegranskat)abstract
- This article discusses the status of the concept of hegemonic masculinity in research on men and boys in Sweden, and how it has been used and developed. Sweden has a relatively long history of public debate, research, and policy intervention in gender issues and gender equality. This has meant, in sheer quantitative terms, a relatively sizeable corpus of work on men, masculinities, and gender relations. There is also a rather wide diversity of approaches, theoretically and empirically, to the analysis of men and masculinities. The Swedish national context and gender equality project is outlined. This is followed by discussion of three broad phases in studies on men and masculinities in Sweden: the 1960s and 1970s before the formulation of the concept of hegemonic masculinity; the 1980s and 1990s when the concept was important for a generation of researchers developing studies in more depth; and the 2000s with a younger generation committed to a variety of feminist and gender critiques other than those associated with hegemonic masculinity. The following sections focus specifically on how the concept of hegemonic masculinity has been used, adapted, and indeed not used, in particular areas of study: boys and young men in family and education; violence; and health. The article concludes with review of how hegemonic masculinity has been used in Swedish contexts, as: gender stereotype, often out of the context of legitimation of patriarchal relations; "Other" than dominant, white middle-class "Swedish," equated with outmoded, nonmodern, working-class, failing boy, or minority ethnic masculinities; a new masculinity concept and practice, incorporating some degree of gender equality; and reconceptualized and problematized as a modern, heteronormative, and subject-centered concept.
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| 10. |
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