| 1. |
- Aad, G., et al.
(författare)
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The ATLAS Experiment at the CERN Large Hadron Collider
- 2008
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Ingår i: Journal of Instrumentation. - 1748-0221. ; 3:S08003
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Forskningsöversikt (refereegranskat)abstract
- The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.
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| 2. |
- Abazov, V. M., et al.
(författare)
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Evidence for production of single top quarks
- 2008
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Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; D:78, s. 012005-
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Forskningsöversikt (refereegranskat)abstract
- We present first evidence for the production of single top quarks in the D0 detector at the Fermilab Tevatron p (p) over bar collider. The standard model predicts that the electroweak interaction can produce a top quark together with an antibottom quark or light quark, without the antiparticle top-quark partner that is always produced from strong-coupling processes. Top quarks were first observed in pair production in 1995, and since then, single top-quark production has been searched for in ever larger data sets. In this analysis, we select events from a 0.9 fb(-1) data set that have an electron or muon and missing transverse energy from the decay of a W boson from the top-quark decay, and two, three, or four jets, with one or two of the jets identified as originating from a b hadron decay. The selected events are mostly backgrounds such as W + jets and t (t) over bar events, which we separate from the expected signals using three multivariate analysis techniques: boosted decision trees, Bayesian neural networks, and matrix-element calculations. A binned likelihood fit of the signal cross section plus background to the data from the combination of the results from the three analysis methods gives a cross section for single top-quark production of sigma(p (p) over bar -> tb + X, tqb + X) = 4.7 +/- 1.3 pb. The probability to measure a cross section at this value or higher in the absence of signal is 0.014%, corresponding to a 3.6 standard deviation significance. The measured cross section value is compatible at the 10% level with the standard model prediction for electroweak top-quark production. We use the cross section measurement to directly determine the Cabibbo-Kobayashi-Maskawa quark mixing matrix element that describes the Wtb coupling and find vertical bar V(tb)f(1)(L)vertical bar = 1.31(-0.21)(+0.25), where f(1)(L) is a generic vector coupling. This model-independent measurement translates into 0.68 <= 1 at the 95% C.L. in the standard model.
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| 3. |
- Abele, H., et al.
(författare)
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Particle physics at the European Spallation Source
- 2023
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Ingår i: Physics reports. - : Elsevier. - 0370-1573 .- 1873-6270. ; 1023, s. 1-84
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Forskningsöversikt (refereegranskat)abstract
- Presently under construction in Lund, Sweden, the European Spallation Source (ESS) will be the world’s brightest neutron source. As such, it has the potential for a particle physics program with a unique reach and which is complementary to that available at other facilities. This paper describes proposed particle physics activities for the ESS. These encompass the exploitation of both the neutrons and neutrinos produced at the ESS for high precision (sensitivity) measurements (searches).
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| 4. |
- Adhikari, Subash, et al.
(författare)
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A high-stringency blueprint of the human proteome
- 2020
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 11:1
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Forskningsöversikt (refereegranskat)abstract
- The Human Proteome Organization (HUPO) launched the Human Proteome Project (HPP) in 2010, creating an international framework for global collaboration, data sharing, quality assurance and enhancing accurate annotation of the genome-encoded proteome. During the subsequent decade, the HPP established collaborations, developed guidelines and metrics, and undertook reanalysis of previously deposited community data, continuously increasing the coverage of the human proteome. On the occasion of the HPP’s tenth anniversary, we here report a 90.4% complete high-stringency human proteome blueprint. This knowledge is essential for discerning molecular processes in health and disease, as we demonstrate by highlighting potential roles the human proteome plays in our understanding, diagnosis and treatment of cancers, cardiovascular and infectious diseases.
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| 5. |
- Alekseev, A. Y., et al.
(författare)
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Structural stability and electronic properties of 2D alkaline-earth metal silicides, germanides, and stannides
- 2020
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Ingår i: Japanese Journal of Applied Physics. - : IOP PUBLISHING LTD. - 0021-4922 .- 1347-4065. ; 59
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Forskningsöversikt (refereegranskat)abstract
- We present the results of an extended theoretical study of the structure, phonon, electronic and optical properties of 2D alkaline-earth metal silicides, germanides and stannides (2D Me2X, where Me=Mg, Ca, Sr, Ba and X=Si, Ge, Sn). The performed analysis has shown the occurrence of the pseudo passivation effect and ionic chemical bonding in these 2D Me2X. In addition, the preformed investigation of their phonon spectra has shown the absence of imaginary frequencies indicating the stability of these 2D structures. The band structure calculations performed using the hybrid functional have revealed that all 2D Me2X are semiconductors with the gap varying from 0.12 to 1.01 eV. Among them Mg- and Ca-based 2D materials are direct band-gap semiconductors with the first direct transition having appreciable oscillator strength. We also propose to consider ternary 2D silicides, germanides and stannides with different Me atoms as a feasible way to modify properties of parent 2D Me2X.
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| 6. |
- Andersson, David A., et al.
(författare)
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First-principles based calculation of binary and multicomponent phase diagrams for titanium carbonitride
- 2008
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Ingår i: Calphad. - : Elsevier BV. - 0364-5916 .- 1873-2984. ; 32:3, s. 543-565
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Forskningsöversikt (refereegranskat)abstract
- In this paper we have used a combined first principles and Calphad approach to calculate phase diagrams in the titanium-carbon-nitrogen system, with particular focus on the vacancy-induced ordering of the substoichiometric carbonitride phase, TiCxNy (x + y <= 1). Results from earlier Monte Carlo simulations of the low-temperature binary phase diagrams are used in order to formulate sublattice models for TiCxNy within the compound energy formalism (CEF) that are capable of describing both the low temperature ordered and the high-temperature disordered state. We parameterize these models using first-principles calculations and then we demonstrate how they can be merged with thermodynamic descriptions of the remaining Ti-C-N phases that are derived within the Calphad method by fitting model parameters to experimental data. We also discuss structural and electronic properties of the ordered end-member compounds, as well as short range order effects in the TiCxNy phase.
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| 7. |
- Bale, S. D., et al.
(författare)
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The FIELDS Instrument Suite for Solar Probe Plus
- 2016
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Ingår i: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 204:1-4, s. 49-82
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Forskningsöversikt (refereegranskat)abstract
- NASA's Solar Probe Plus (SPP) mission will make the first in situ measurements of the solar corona and the birthplace of the solar wind. The FIELDS instrument suite on SPP will make direct measurements of electric and magnetic fields, the properties of in situ plasma waves, electron density and temperature profiles, and interplanetary radio emissions, amongst other things. Here, we describe the scientific objectives targeted by the SPP/FIELDS instrument, the instrument design itself, and the instrument concept of operations and planned data products.
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| 8. |
- Baumjohann, W., et al.
(författare)
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Dynamics of thin current sheets : Cluster observations
- 2007
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Ingår i: Annales Geophysicae. - : Copernicus GmbH. - 0992-7689 .- 1432-0576. ; 25:6, s. 1365-1389
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Forskningsöversikt (refereegranskat)abstract
- The paper tries to sort out the specific signatures of the Near Earth Neutral Line (NENL) and the Current Disruption (CD) models. and looks for these signatures in Cluster data from two events. For both events transient magnetic si-natures are observed, together with fast ion flows. In the simplest form of NENL scenario, with a large-scale two-dimensional reconnection site, quasi-invariance along Y is expected. Thus the magnetic signatures in the S/C frame are interpreted as relative motions, along the X or Z direction, of a quasi-steady X-line, with respect to the S/C. In the simplest form of CD scenario an azimuthal modulation is expected. Hence the signatures in the S/C frame are interpreted as signatures of azimuthally (along Y) moving current system associated with low frequency fluctuations of J(y) and the corresponding field-aligned currents Event I covers a pseudo-breakup, developing only at high latitudes. First, a thin (H approximate to 2000Km approximate to 2 rho(i), with pi the ion gyroradius) Current Sheet (CS) is found to be quiet. A slightly thinner CS (H approximate to 1000-2000 km approximate to 1-2 rho(i)), crossed about 30 min later, is found to be active. with fast earthward ion flow bursts (300-600 km/s) and simultaneous large amplitude fluctuations (delta B/B similar to 1). In the quiet CS the current density J(y) is carried by ions. Conversely, in the active CS ions are moving eastward; the westward current is carried by electrons that move eastward, faster than ions. Similarly, the velocity of earthward flows (300-600 km/s), observed during the active period. maximizes near or at the CS center. During the active phase of Event I no signature of the crossing of an X-line is identified, but an X-line located beyond Cluster could account for the observed ion flows, provided that it is active for at least 20 min. Ion flow bursts can also be due to CD and to the corresponding dipolarizations which are associated with changes in the current density. Yet their durations are shorter than the duration of the active period. While the overall partial derivative Bz/partial derivative t is too weak to accelerate ions up to the observed velocities, short duration partial derivative B-z/partial derivative t can produce the azimuthal electric field requested to account for the observed ion flow bursts. The corresponding large amplitude perturbations are shown to move eastward. which suggests that the reduction in the tail current could be achieved via a series of eastward traveling partial dipolarisations/CD. The second event is much more active than the first one. The observed flapping of the CS corresponds to an azimuthally propagating wave. A reversal in the proton flow velocity, from 1000 to + 1000 km/s, is measured by CODIF. The overall flow reversal, the associated change in the sign of B-z and the relationship between B-x and B-y suggest that the spacecraft are moving with respect to an X-line and its associated Hall-structure. Yet, a simple tailward retreat of a large-scale X-line cannot account for all the observations, since several flow reversals are observed. These quasi-periodic flow reversals can also be associated with an azimuthal motion of the low frequency oscillations. Indeed, at the beginning of the interval B-y varies rapidly along the Y direction; the magnetic signature is three-dimensional and essentially corresponds to a structure of filamentary field-aligned current, moving eastward at similar to 200 km/s. The transverse size of the structure is similar to 1000 km. Similar structures are observed before and after. Thesefilamentary structures are consistent with an eastward propagation of an azimuthal modulation associated with a current system J(y), J(x). During Event 1, signatures of filamentary field-aligned current structures are also observed, in association with modulations of J(y). Hence, for both events the structure of the magnetic fields and currents is three-dimensional.
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| 9. |
- Berglund, Lisa, et al.
(författare)
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A genecentric Human Protein Atlas for expression profiles based on antibodies
- 2008
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Ingår i: Molecular & Cellular Proteomics. - 1535-9476 .- 1535-9484. ; 7:10, s. 2019-2027
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Forskningsöversikt (refereegranskat)abstract
- An attractive path forward in proteomics is to experimentally annotate the human protein complement of the genome in a genecentric manner. Using antibodies, it might be possible to design protein-specific probes for a representative protein from every protein-coding gene and to subsequently use the antibodies for systematical analysis of cellular distribution and subcellular localization of proteins in normal and disease tissues. A new version (4.0) of the Human Protein Atlas has been developed in a genecentric manner with the inclusion of all human genes and splice variants predicted from genome efforts together with a visualization of each protein with characteristics such as predicted membrane regions, signal peptide, and protein domains and new plots showing the uniqueness (sequence similarity) of every fraction of each protein toward all other human proteins. The new version is based on tissue profiles generated from 6120 antibodies with more than five million immunohistochemistry-based images covering 5067 human genes, corresponding to approximately 25% of the human genome. Version 4.0 includes a putative list of members in various protein classes, both functional classes, such as kinases, transcription factors, G-protein-coupled receptors, etc., and project-related classes, such as candidate genes for cancer or cardiovascular diseases. The exact antigen sequence for the internally generated antibodies has also been released together with a visualization of the application-specific validation performed for each antibody, including a protein array assay, Western blot analysis, immunohistochemistry, and, for a large fraction, immunofluorescence-based confocal microscopy. New search functionalities have been added to allow complex queries regarding protein expression profiles, protein classes, and chromosome location. The new version of the protein atlas thus is a resource for many areas of biomedical research, including protein science and biomarker discovery.
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| 10. |
- Bern, Zvi, et al.
(författare)
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The SAGEX review on scattering amplitudes Chapter 2 : An invitation to color-kinematics duality and the double copy
- 2022
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Ingår i: Journal of Physics A. - : IOP Publishing. - 1751-8113 .- 1751-8121. ; 55:44
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Forskningsöversikt (refereegranskat)abstract
- Advances in scattering amplitudes have exposed previously-hidden color-kinematics and double-copy structures in theories ranging from gauge and gravity theories to effective field theories such as chiral perturbation theory and the Born-Infeld model. These novel structures both simplify higher-order calculations and pose tantalizing questions related to a unified framework underlying relativistic quantum theories. This introductory mini-review article invites further exploration of these topics. After a brief introduction to color-kinematics duality and the double copy as they emerge at tree and loop-level in gauge and gravity theories, we present two distinct examples: (1) an introduction to the web of double-copy-constructible theories, and (2) a discussion of the application of the double copy to calculation relevant to gravitational-wave physics.
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