Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "LAR1:uu ;mspu:(researchreview)"

Sökning: LAR1:uu > Forskningsöversikt

Sortera/gruppera träfflistan
  • Aad, G., et al. (författare)
  • The ATLAS Experiment at the CERN Large Hadron Collider
  • 2008
  • Ingår i: Journal of Instrumentation. - IOP Publishing. - 1748-0221. ; 3:S08003
  • Forskningsöversikt (refereegranskat)abstract
    • The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.
  • Abacan, MaryAnn, et al. (författare)
  • The Global State of the Genetic Counseling Profession
  • 2019
  • Ingår i: European Journal of Human Genetics. - NATURE PUBLISHING GROUP. - 1018-4813 .- 1476-5438. ; 27:2, s. 183-197
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • The profession of genetic counseling (also called genetic counselling in many countries) began nearly 50 years ago in the United States, and has grown internationally in the past 30 years. While there have been many papers describing the profession of genetic counseling in individual countries or regions, data remains incomplete and has been published in diverse journals with limited access. As a result of the 2016 Transnational Alliance of Genetic Counseling (TAGC) conference in Barcelona, Spain, and the 2017 World Congress of Genetic Counselling in the UK, we endeavor to describe as fully as possible the global state of genetic counseling as a profession. We estimate that in 2018 there are nearly 7000 genetic counselors with the profession established or developing in no less than 28 countries.
  • Abada, A., et al. (författare)
  • FCC Physics Opportunities Future Circular Collider Conceptual Design Report Volume 1
  • 2019
  • Ingår i: European Physical Journal C. - 1434-6044 .- 1434-6052. ; 79:6
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • We review the physics opportunities of the Future Circular Collider, covering its e(+)e(-), pp, ep and heavy ion programmes. We describe the measurement capabilities of each FCC component, addressing the study of electroweak, Higgs and strong interactions, the top quark and flavour, as well as phenomena beyond the Standard Model. We highlight the synergy and complementarity of the different colliders, which will contribute to a uniquely coherent and ambitious research programme, providing an unmatchable combination of precision and sensitivity to new physics.
  • Abazov, V. M., et al. (författare)
  • Evidence for production of single top quarks
  • 2008
  • Ingår i: Physical Review D. - 1550-7998. ; 78:1, s. 012005
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • We present first evidence for the production of single top quarks in the D0 detector at the Fermilab Tevatron p (p) over bar collider. The standard model predicts that the electroweak interaction can produce a top quark together with an antibottom quark or light quark, without the antiparticle top-quark partner that is always produced from strong-coupling processes. Top quarks were first observed in pair production in 1995, and since then, single top-quark production has been searched for in ever larger data sets. In this analysis, we select events from a 0.9 fb(-1) data set that have an electron or muon and missing transverse energy from the decay of a W boson from the top-quark decay, and two, three, or four jets, with one or two of the jets identified as originating from a b hadron decay. The selected events are mostly backgrounds such as W + jets and t (t) over bar events, which we separate from the expected signals using three multivariate analysis techniques: boosted decision trees, Bayesian neural networks, and matrix-element calculations. A binned likelihood fit of the signal cross section plus background to the data from the combination of the results from the three analysis methods gives a cross section for single top-quark production of sigma(p (p) over bar -> tb + X, tqb + X) = 4.7 +/- 1.3 pb. The probability to measure a cross section at this value or higher in the absence of signal is 0.014%, corresponding to a 3.6 standard deviation significance. The measured cross section value is compatible at the 10% level with the standard model prediction for electroweak top-quark production. We use the cross section measurement to directly determine the Cabibbo-Kobayashi-Maskawa quark mixing matrix element that describes the Wtb coupling and find vertical bar V(tb)f(1)(L)vertical bar = 1.31(-0.21)(+0.25), where f(1)(L) is a generic vector coupling. This model-independent measurement translates into 0.68 <= 1 at the 95% C.L. in the standard model.
  • Abbott, Jessica K. (författare)
  • Intra-locus sexual conflict and sexually antagonistic genetic variation in hermaphroditic animals
  • 2011
  • Ingår i: Proceedings of the Royal Society of London. Biological Sciences. - 0962-8452 .- 1471-2954. ; 278:1703, s. 161-169
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • Intra-locus sexual conflict results when sex-specific selection pressures for a given trait act against the intra-sexual genetic correlation for that trait. It has been found in a wide variety of taxa in both laboratory and natural populations, but the importance of intra-locus sexual conflict and sexually antagonistic genetic variation in hermaphroditic organisms has rarely been considered. This is not so surprising given the conceptual and theoretical association of intra-locus sexual conflict with sexual dimorphism, but there is no a priori reason why intra-locus sexual conflict cannot occur in hermaphroditic organisms as well. Here, I discuss the potential for intra-locus sexual conflict in hermaphroditic animals and review the available evidence for such conflict, and for the existence of sexually antagonistic genetic variation in hermaphrodites. I argue that mutations with asymmetric effects are particularly likely to be important in mediating sexual antagonism in hermaphroditic organisms. Moreover, sexually antagonistic genetic variation is likely to play an important role in inter-individual variation in sex allocation and in transitions to and from gonochorism (separate sexes) in simultaneous hermaphrodites. I also describe how sequential hermaphrodites may experience a unique form of intra-locus sexual conflict via antagonistic pleiotropy. Finally, I conclude with some suggestions for further research.
  • Abbott, Jessica K., et al. (författare)
  • Obtaining snapshots of genetic variation using hemiclonal analysis
  • 2011
  • Ingår i: Trends in Ecology & Evolution. - 0169-5347 .- 1872-8383. ; 26:7, s. 359-368
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • Hemiclones are naturally occurring or artificially produced individuals that share a single specific genetic haplotype. Natural hemiclones are produced via hybridization between two closely related species, whereas hemiclonal analysis in Drosophila is carried out in the laboratory via crosses with artificially created 'clone-generator' females with a specific genetic make-up. Hemiclonal analysis in Drosophila has been applied successfully to date to obtain measures of standing genetic variation for numerous traits. Here, we review the current hemiclonal literature and suggest future directions for hemiclonal research, including its application in molecular and genomic studies, and the adaptation of natural hemiclonal systems to carry out Drosophila-type studies of standing genetic variation.
  • Abbott, R., et al. (författare)
  • Hybridization and speciation
  • 2013
  • Ingår i: Journal of Evolutionary Biology. - 1010-061X .- 1420-9101. ; 26:2, s. 229-246
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • Hybridization has many and varied impacts on the process of speciation. Hybridization may slow or reverse differentiation by allowing gene flow and recombination. It may accelerate speciation via adaptive introgression or cause near-instantaneous speciation by allopolyploidization. It may have multiple effects at different stages and in different spatial contexts within a single speciation event. We offer a perspective on the context and evolutionary significance of hybridization during speciation, highlighting issues of current interest and debate. In secondary contact zones, it is uncertain if barriers to gene flow will be strengthened or broken down due to recombination and gene flow. Theory and empirical evidence suggest the latter is more likely, except within and around strongly selected genomic regions. Hybridization may contribute to speciation through the formation of new hybrid taxa, whereas introgression of a few loci may promote adaptive divergence and so facilitate speciation. Gene regulatory networks, epigenetic effects and the evolution of selfish genetic material in the genome suggest that the Dobzhansky-Muller model of hybrid incompatibilities requires a broader interpretation. Finally, although the incidence of reinforcement remains uncertain, this and other interactions in areas of sympatry may have knock-on effects on speciation both within and outside regions of hybridization.
  • Abdelmoniem, Amr M., et al. (författare)
  • Synthesis, Chemistry and Utilities of Diaminoazoles with Special Reference to 3,5-Diaminopyrazoles
  • 2018
  • Ingår i: Current Organic Synthesis. - BENTHAM SCIENCE PUBL LTD. - 1570-1794 .- 1875-6271. ; 15:4, s. 487-514
  • Forskningsöversikt (övrigt vetenskapligt)abstract
    • Background: Although the chemistry of heteroaromatic monoamino azoles has been surveyed more than once in the last decade, the chemistry of the di- and triaminoazoles has not been reviewed. In this article we will survey the synthesis, chemistry and utility of the diaminoazoles. In this review, the chemistry of the diaminoazoles as well as their most important utilities will be surveyed. Objective: The review focuses on recent progress in diaminoazoles (i.e. diaminopyrazoles, diaminoimidazoles, diaminotriazoles and diaminothiazole) with especial references to diaminopyrazoles. The synthesis as well as pharmaceutical utilities are reported. There are several methods for synthesis of diaminopyrazoles. 3,5-Diaminopyrazole and its derivatives are prepared through the reaction of malononitrile or arylhydrazononitrile with hydrazine derivatives. 3,4-Diaminopyrazoles are prepared via nitration of 3-aminopyrazole with subsequent reduction of the produced compound. The diaminopyrazoles have several applications in cosmetic and pharmaceutical industries. They also have useful utilities as a constituent in oxidative hair dyes. Conclusion: We managed to report the common methods for the synthesis of diaminoazoles with especial reference to aminopyrazoles that are prepared through the reaction of malononitrile or hydrazononitriles with hydrazine derivatives. Some important applications that include pharmaceutical utilities such as hair dye constituents are reported.
Skapa referenser, mejla, bekava och länka
fritt online (669)
Typ av publikation
Typ av innehåll
övrigt vetenskapligt (2651)
populärvet., debatt m.m. (259)
refereegranskat (216)
Schiöth, Helgi B., (31)
Nilsson, Bo, (26)
Björck, Martin, (22)
Heldin, Carl-Henrik, (22)
Rosenquist, Richard, (20)
Wanhainen, Anders, (20)
visa fler...
Öberg, Kjell, (20)
Nilsson Ekdahl, Kris ... (18)
Hedenstierna, Göran, (18)
El-Seedi, Hesham, (16)
Cederholm, Tommy, (16)
Andersson, Dan I., (16)
Bergqvist, David, (15)
Rönnblom, Lars, (15)
Lennernäs, Hans, (15)
Glimelius, Bengt, (14)
Li, Jin-Ping, (14)
Ellegren, Hans, (14)
Eklund, Matti, 1974- ... (13)
Holmes, Emily A., (13)
Lindblad, Peter, (13)
Wadelius, Mia, (13)
Zhang, Haibo, (13)
Bonten, Marc (13)
Antonelli, Massimo (13)
Chastre, Jean (13)
Citerio, Giuseppe (13)
Conti, Giorgio (13)
Macrae, Duncan (13)
Mancebo, Jordi (13)
Maggiore, Salvatore ... (13)
Claesson-Welsh, Lena ... (11)
Pontén, Fredrik, (11)
Gustafsson, Bengt (11)
Westermark, Per (11)
De Backer, Daniel (11)
Landegren, Ulf, (10)
Janson, Christer (10)
Stamatopoulos, Kosta ... (10)
Nyström, Staffan, 19 ... (10)
El-Seedi, Hesham R., (9)
Hughes, Diarmaid, 19 ... (9)
Fredriksson, Robert, (9)
NIlsson, Ingela, 197 ... (9)
Cars, Otto, (9)
Bohlin, Lars, (9)
Wallentin, Lars, 194 ... (9)
Hughes, Diarmaid, (9)
Azoulay, Elie (9)
Gerlach, Herwig (9)
visa färre...
Uppsala universitet (3052)
Stockholms universitet (52)
Lunds universitet (48)
Linköpings universitet (45)
Umeå universitet (37)
Göteborgs universitet (21)
visa fler...
Kungliga Tekniska Högskolan (21)
Örebro universitet (19)
Linnéuniversitetet (19)
Högskolan i Gävle (6)
Karolinska Institutet (6)
Mittuniversitetet (5)
Högskolan Dalarna (2)
Luleå tekniska universitet (1)
Mälardalens högskola (1)
Högskolan i Jönköping (1)
Högskolan i Skövde (1)
RISE (1)
Karlstads universitet (1)
Sophiahemmet Högskola (1)
Röda Korsets Högskola (1)
visa färre...
Engelska (2791)
Svenska (218)
Tyska (7)
Italienska (4)
Hindi (4)
Finska (3)
visa fler...
Polska (3)
Ungerska (3)
Norska (2)
Spanska (2)
Estniska (2)
Portugisiska (1)
Kinesiska (1)
visa färre...
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (1654)
Naturvetenskap (874)
Humaniora (277)
Samhällsvetenskap (165)
Teknik (118)
Lantbruksvetenskap (10)


pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy