| 1. |
- Arnadottir, Solrun Dogg, et al.
(författare)
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Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki : Aðdragandi og áhættuþættir
- 2024
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Ingår i: Laeknabladid. - : LAEKNAFELAG ISLANDS-ICELANDIC MEDICAL ASSOCIATION. - 0023-7213 .- 1670-4959. ; 110:1, s. 20-27
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: No recent studies exist on lower extremity amputations (LLAs) in Iceland. The aim of this study was to investigate LLA incidence in Iceland 2010-2019 and preceding procedures in amputations induced by peripheral arterial disease (PAD) and diabetes mellitus (DM).MATERIAL AND METHODS: Retrospective study on clinical records of all patients (>18 years) who underwent LLA in Iceland's two main hospitals during 2010-2019. Patients were excluded if LLA was performed for reasons other than DM and/or PAD. Symptoms, medication and circulation assessment were recorded from first hospital visit due to symptoms, and prior to the last LLA, respectively. Previous arterial surgeries and amputations were also recorded.RESULTS: A total of 167 patients underwent LLA. Thereof, 134 (77 ± 11 years, 93 men and 41 woman) due to DM and/or PAD. The LLA-rate due to those diseases increased from 4.1/100,000 inhabitants in 2010-2013 to 6.7/100,000 in 2016-2019 (p=0,04). Risk factors were mainly hypertension, 84%, and smoking, 69%. Chronic limb -threatening ischemia induced 71% of first hospital visits. Revascularisations were performed (66% endovascular) in 101 patients. Non -diabetic patients were 52% and had statins less frequently prescribed than DM patients (26:45, p<0.001).CONCLUSION: DM and/or PAD are the leading causes of LLA in Iceland. Amputation rate increased during the period but is low in an international context. Amputation is most often preceded by arterial surgery. DM is present in almost half of cases, similar or less than in most other countries. Opportunities for improved prevention should aim on earlier diagnosis and preventive treatment of non -diabetic individuals with PAD.
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| 2. |
- Garoarsdottir, Helga Run, et al.
(författare)
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Árangur kransæðahjáveituaðgerða hjá konum á Íslandi
- 2018
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Ingår i: Laeknabladid. - : LAEKNAFELAG ISLANDS-ICELANDIC MEDICAL ASSOC. - 0023-7213 .- 1670-4959. ; 104:7-8, s. 335-340
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Tidskriftsartikel (refereegranskat)abstract
- InngangurMarkmið þessarar rannsóknar var að bera saman árangur kransæða-hjáveituaðgerða hjá konum og körlum á Íslandi með áherslu á snemm- og síðkomna fylgikvilla, 30 daga dánartíðni og langtímalifun.Efniviður og aðferðirAfturskyggn rannsókn á öllum sjúklingum sem gengust undir kransæðahjáveituaðgerð á Íslandi á árunum 2001-2013. Upplýsingar fengust úr sjúkraskrám og Dánarmeinaskrá Embættis landlæknis. Fylgikvillum var skipt í snemm- og síðkomna fylgikvilla og heildarlif-un reiknuð með aðferð Kaplan-Meier. Fjölþátta aðhvarfsgreining var notuð til að meta forspárþætti dauða innan 30 daga og Cox aðhvarfs-greining til að meta forspárþætti verri langtímalifunar. Meðaleftirfylgd var 6,8 ár. NiðurstöðurAf 1755 sjúklingum voru 318 konur (18%). Meðalaldur þeirra var fjórum árum hærri en karla (69 ár á móti 65 árum, p<0,001), þær höfðu oftar sögu um háþrýsting (72% á móti 64%, p=0,009) og EuroSCOREst þeirra var hærra (6,1 á móti 4,3, p<0,001). Hlutfall annarra áhættu-þátta eins og sykursýki var hins vegar sambærilegt, líkt og útbreiðsla kransæðasjúkdóms. Alls létust 12 konur (4%) og 30 karlar (2%) innan 30 daga frá aðgerð en munurinn var ekki marktækur (p=0,08). Tíðni snemmkominna fylgikvilla, bæði minniháttar (53% á móti 48% p=0,07) og alvarlegra (13% á móti 11%, p=0,2), var sambærileg. Fimm árum frá aðgerð var lifun kvenna 87% borin saman við 90% hjá körlum (p=0,09). Þá var tíðni síðkominna fylgikvilla sambærileg hjá konum og körlum 5 árum frá aðgerð (21% á móti 19%, p=0,3). Kvenkyn reyndist hvorki sjálfstæður forspárþáttur 30 daga dánartíðni (OR 0,99; 95%-ÖB: 0,97-1,01) né verri lifunar (HR 1,08; 95%-ÖB: 0,82-1,42).Ályktun Mun færri konur en karlar gangast undir kransæðahjáveituaðgerð á Íslandi og eru þær fjórum árum eldri þegar kemur að aðgerð. Árangur kransæðahjáveitu er góður hjá konum líkt og körlum, en 5 árum eftir aðgerð eru 87% kvenna á lífi.
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| 3. |
- Gunnarsdottir, Anna Gudlaug, et al.
(författare)
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Snemmkominn árangur opinna ósæðarlokuskipta við ósæðarlokuþrengslum hjá konum á Íslandi
- 2019
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Ingår i: Laeknabladid. - : Laeknabladid/The Icelandic Medical Journal. - 0023-7213 .- 1670-4959. ; 105:5, s. 215-221
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Aortic valve replacement (AVR) for aortic stenosis (AS) is the second most common open-heart procedure performed in Iceland. The aim of this study was to analyze the early outcome of AVR among females in Iceland.Materials and methods: This was a retrospective study including 428 patients who underwent surgical AVR due to AS in Iceland from 2002-2013. Information was gathered from medical records, including pre-and postoperative results of echocardiography and complications. Overall survival was estimated (Kaplan-Meier) and logistic regression used to identify predictors of operative mortality. The median follow-up time was 8.8 years (0-16.5 years).Results: Of the 428 patients, 151 were female (35.3%), that were on average 2 years older than men (72.6 ± 9.4 vs. 70.4 ± 9.8 yrs., p=0.020). Preoperative symptoms were similar, but women had significantly higher EurosSCORE II than men (5.2 ± 8.8 vs. 3.2 ± 4.6, p=0.002). Maximal pressure-gradient across the aortic valve was higher for women (74.4 ± 29.3 mmHg vs. 68.0 ± 23.4 mmHg, p=0,013) but postoperative complications, operative mortality (8.6% vs. 4.0%, p=0.068) and 5-year survival (78.6% vs. 83.1%, p=0.245) were comparable for women and men. Logistic regression analysis showed that female gender was not an independent predictor of 30-day mortality (OR 1.54, 95% CI 0.63-3.77).Conclusions: Females constitute one third of patients that undergo AVR for AS in Iceland. At the time of surgery females are two years older than men and appear to have a more significant aortic stenosis at the time of surgery. However, complication rates, operative mortality and long-term survival were comparable for both genders.
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| 4. |
- Birgisson, Helgi, et al.
(författare)
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Skimun fyrir krabbameinum í ristli og endaþarmi : Yfirlitsgrein um nýgengi, dánartíðni, kostnað og árangur
- 2021
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Ingår i: Laeknabladid. - : LAEKNAFELAG ISLANDS-ICELANDIC MEDICAL ASSOC. - 0023-7213 .- 1670-4959. ; 107:9, s. 398-405
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Forskningsöversikt (refereegranskat)abstract
- In this article the incidence and mortality for cancer of the colon and rectum in Iceland is discussed. The two most common screening methods, faecal immunochemical test (FIT) and colonoscopy are compared and an estimate of cost and benefits for the Icelandic society will be made. The incidence of cancer of the colon and rectum has been increasing in Iceland in last decades but mortality has decreased and survival improved. However, more individuals die from cancer of the colon and rectum than from both breast-and cervical cancer added together. It is likely that screening for cancer of the colon and rectum, could prevent at least 6 of the 28 deaths related to those cancers, occurring yearly in Iceland in screening age, given a screening ages of 50-74 years. The extra cost for the Icelandic community due to the implementation of screening for cancer of the colon and rectum will be acceptable due to the lower cost of simpler treatments, lower cancer incidence and reduced mortality.
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| 5. |
- Gunnarsdottir, Guorun Mist, et al.
(författare)
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Endurtekin krampaköst hjá ungri konu : sjúkratilfelli
- 2016
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Ingår i: Laeknabladid. - : Laeknabladid/The Icelandic Medical Journal. - 0023-7213. ; 102:7-8, s. 339-342
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Tidskriftsartikel (refereegranskat)abstract
- 18 ára hraust stúlka kom endurtekið á slysadeild á 6 vikna tímabili vegna krampakasta. Engin fyrri saga var um flogaveiki og hún tók engin lyf. Myndrannsóknir og heilalínurit bentu ekki til flogaveiki. Hún mældist með lækkaðan blóðsykur í tvígang á slysadeild, 1,3 mmól/L og 1,7 mmól/L (4,0-6,0 mmól/L). Vaknaði þá grunur um insúlínmyndandi æxli. Gerð var víðtæk leit að æxlisvexti sem bar engan árangur. Var hún því send erlendis í frekari uppvinnslu, meðal annars í jáeindaskanna og sérhæfða æðamyndatöku. Hún var að lokum greind með nesidioblastosis. Hér verður fjallað um sjúkratilfellið auk yfirferðar um þennan sjaldgæfa sjúkdóm og uppvinnslu á honum.
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| 6. |
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| 7. |
- Svanbergsson, Gunnar, et al.
(författare)
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Segulómun við greiningu lendahryggsverkja : Nýting, samband við einkenni og áhrif á meðferð
- 2017
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Ingår i: LAEKNABLADID. - : Laeknabladid/The Icelandic Medical Journal. - 0023-7213. ; 103:1, s. 17-22
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Tidskriftsartikel (refereegranskat)abstract
- Background: Non-specific low-back pain is a worldwide problem. More specific diagnosis could improve prognosis. Magnetic resonance imaging (MRI) became available in Akureyri Hospital in 2004 but its utilisation in diagnosing low-back pain has not been investigated. Objective: To study the use of MRI in diagnosing low-back pain, correlation of the MRI outcomes with other clinical findings and its possible effects on treatment. Methods: Retrospective, descriptive analysis of patients' journals. Included were all adult (18 years and older) residents of Akureyri who underwent low-back MRI in Akureyri Hospital in 2009. Results: During 2009, 169 patients (82 women) underwent low-back MRI, mean age 51 years (18-88). The most common pathological findings were connected to the lumbar disk. Disk herniation was diagnosed in 38% of the patients, 77% at the L4-L5 or L5-S1 level. MRI results correlated poorly with symptoms and clinical findings. Treatment options for disk herniation were prescription of medications (70%), referrals to physiotherapy (67%) and orthopaedic surgeons (61%). Nine patients were operated. Among patients referred to physiotherapy, 49% were first examined with MRI and thus waited longer for referral than those referred directly to physiotherapy (p=0.008). One year after the MRI, recovery rate was 51%. Prognosis was better for patients referred to physiotherapy (p=0.024). Conclusions: MRI seems to be used for general diagnosis of low-back pain. Symptoms and MRI results correlate poorly, emphasizing the need for the doctor's thorough weighing of clinical and MRI findings when diagnosing low-back pain. Recovery rate of patients with lumbar disk herniation improves by physiotherapy. The general use of MRI might delay treatment.
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