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Träfflista för sökning "LAR1:gu ;lar1:(cth);srt2:(1995-1999);srt2:(1999)"

Search: LAR1:gu > Chalmers University of Technology > (1995-1999) > (1999)

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1.	Abel, Frida, 1974, et al. (author) Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24. 1999 In: British journal of cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 81:8, s. 1402-9 Journal article (peer-reviewed)abstract Deletion of chromosome arm 1p and amplification of the MYCN oncogene are well-recognized genetic alterations in neuroblastoma cells. Recently, another alteration has been reported; gain of the distal part of chromosome arm 17q. In this study 48 neuroblastoma tumours were successfully analysed for 17q status in relation to known genetic alterations. Chromosome 17 status was detected by fluorescence in situ hybridization (FISH). Thirty-one of the 48 neuroblastomas (65%) showed 17q gain, and this was significantly associated with poor prognosis. As previously reported, 17q gain was significantly associated with metastatic stage 4 neuroblastoma and more frequently detected than both deletion of chromosome arm 1p and MYCN amplification in tumours of all stages. 17q gain also showed a strong correlation to survival probability (P = 0.0009). However, the most significant correlation between 17q gain and survival probability was observed in children with low-stage tumours (stage 1, 2, 3 and 4S), with a survival probability of 100% at 5 years from diagnosis for children with tumours showing no 17q gain compared to 52.5% for those showing 17q gain (P = 0.0021). This suggests that 17q gain as a prognostic factor plays a more crucial role in low-stage tumours. Expression of the somatostatin receptor 2 (SSTR2), localized in chromosome region 17q24, has in previous studies been shown to be positively related to survival in neuroblastoma. A point mutation in the SSTR2 gene has earlier been reported in a human small-cell lung cancer. In this study, mutation screening of the SSTR2 gene in 43 neuroblastoma tumours was carried out with polymerase chain reaction-based single-stranded conformation polymorphism/heteroduplex (SSCP/HD) and DNA sequencing, and none of the tumours showed any aberrations in the SSTR2 gene. These data suggest that mutations in the SSTR2 gene are uncommon in neuroblastoma tumours and do not correlate with either the 17q gain often seen or the reason some tumours do not express SSTR2 receptors. Overall, this study indicates that gain of chromosome arm 17q is the most frequently occurring genetic alteration, and that it is associated with established prognostic factors.
2.	Abul Milh, Miroslawa, et al. (author) International field intercomparison of methods to speciate mercury in simulated flue gas 1999 In: Book of Abstract. 5th International Conference on Mercury as a Global Pollutant, Rio de Janeiro, Brazil, (1999). Conference paper (other academic/artistic)
3.	Adolfsson, Tobias, 1970 (author) Partial least squares and its implementations from a statistical point of view 1999 Licentiate thesis (other academic/artistic)
4.	Andersson, Mats, 1957, et al. (author) A constructive proof of the composition rule for Taylor's functional calculus 1999 Other publication (other academic/artistic)
5.	Andlid, Thomas, 1963, et al. (author) Characterization of Saccharomyces cerevisiae CBS 7764 isolated from rainbow trout intestine 1999 In: Systematic and Applied Microbiology. ; 22, s. 145-155 Journal article (peer-reviewed)
6.	Arkeryd, Leif, 1940, et al. (author) On the Milne problem and the hydrodynamic limit for a steady Boltzmann equation model 1999 Other publication (other academic/artistic)
7.	Arkeryd, Leif, 1940 (author) On the stationary oltzmann equation in Rn 1999 Other publication (other academic/artistic)
8.	Asadzadeh, Mohammad, 1952 (author) Characteristic Methods for Fokker-Planck and Fermi Pencil Beam Equations 1999 In: Proceedings of 21th International Symposium on Rarefied Gas Dynamics, ed. by R. Brun et al , Marseille 1998. ; 2, s. 205-212 Conference paper (peer-reviewed)abstract We design an efficient and accurate numerical method for the pencil beam equations based on the principle of solving i) An {\sl exact transport} problem on each collision free spatial segment: Let $x$ be the beam penetration direction, $\{x_{n}\}$ an increasing sequence of discrete points indicating collision sites and $\{\mathcal{V}_{n}\}$ be a corresponding sequence of piecewise polynomial spaces on meshes $\{\mathcal{T}_{n}\}$ on the transversal variable $x_{\perp}$. Then given the approximate solution $J^{h,n}\in\mathcal{V}_{n}$ at the collision site $x_{n}$ solve the pencil beam equation exactly on the collision free interval $(x_{n},x_{n+1})$ with the data $J^{h,n}$ to give the solution $J^{h,n+1}_{-}$ at the next collision site $x_{n+1}$, before the collision. ii) A {\sl projection}: Compute $J^{h,n+1}=\mathcal{P}_{n+1}J^{h,n+1}_{-}$, with $\mathcal{P}_{n+1}$ being a projection into $\{\mathcal{V}_{n+1}\}$.
9.	Asadzadeh, Mohammad, 1952 (author) Convergence of a discontinuousi Galerkin scheme for the neutron transport 1999 Other publication (other academic/artistic)
10.	Beilina, Larisa, 1970 (author) Osmotic mass transfer through a cylindric semipermeable membrane 1999 Other publication (other academic/artistic)

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Result 1-10 of 105

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Type of publication: other publication (46); journal article (29); licentiate thesis (13); conference paper (9); doctoral thesis (3); book chapter (3); show more...; book (1); research review (1); show less...

Type of content: other academic/artistic (70); peer-reviewed (35)

Author/Editor: Patriksson, Michael, ... (4); Lindqvist, Oliver, 1 ... (3); Stolin, Alexander, 1 ... (3); Feng, Xinbin (3); Strömberg, Dan, 1959 (3); Wennberg, Bernt, 196 ... (3); show more...; Wijk, Helle, 1958 (3); Abul Milh, Miroslawa (2); Sommar, Jonas (2); Steif, Jeffrey, 1960 (2); Carlson, Johan, 1972 (2); Engström, Tomas, 195 ... (2); Steen, B (2); Asadzadeh, Mohammad, ... (2); Li, H. (1); Gustafsson, L (1); Johansson, Henrik (1); Carlsson, Nils-Gunna ... (1); Molander, Sverker, 1 ... (1); Hernandez, A (1); Abel, Frida, 1974 (1); Kogner, Per (1); Nilsson, Staffan, 19 ... (1); Ejeskär, Katarina, 1 ... (1); Martinsson, Tommy, 1 ... (1); Blomberg, Anders, 19 ... (1); Cooper, David (1); Hong, B (1); Ikävalko, E (1); Jormanainen, P (1); Munthe, John (1); Siemens, V (1); Iverfeldt, Åke (1); Larjava, K (1); Andersson, Mats, 195 ... (1); Tamás, Markus J., 19 ... (1); Adolfsson, Tobias, 1 ... (1); Mazorchuk, Volodymyr (1); Luyten, K. (1); Schwab, C. (1); Helenius, Ola, 1970 (1); Brune, Mats, 1950 (1); Sandberg, Ann-Sofie, ... (1); Hohmann, Stefan, 195 ... (1); Turowska, Lyudmila, ... (1); Gustafsson, Lena, 19 ... (1); Andlid, Thomas, 1963 (1); Beilina, Larisa, 197 ... (1); Pettersson, Rolf, 19 ... (1); Strömberg, Ann-Brith ... (1); show less...

University: University of Gothenburg (105); Chalmers University of Technology (105)Undo refine; RISE (2); Karolinska Institutet (1)

Language: English (103); Swedish (2)

Research subject (UKÄ/SCB): Natural sciences (92); Social Sciences (6); Medical and Health Sciences (5); Humanities (5); Engineering and Technology (4); Agricultural Sciences (1)

Year: 1999 (105)Undo refine

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