| 1. |
- Aalders, Johannes Theodor, et al.
(författare)
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Blogal Studies in 2020 and Beyond
- 2020
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Ingår i: School of Blogal Studies.
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Annan publikation (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Aalders, Johannes Theodor, et al.
(författare)
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Drawing together: Making Marginal Futures Visible through Collaborative Comic Creation (CCC)
- 2020
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Ingår i: Geographica Helvetica. The Swiss Journal of Geography. - : Copernicus GmbH. - 0016-7312. ; 75, s. 415-430
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Tidskriftsartikel (refereegranskat)abstract
- The article introduces collaborative comic creation (CCC) as a methodological tool. The central question it addresses is how marginalised imaginations of futures can be made visible in the context of the planned Lamu Port-South Sudan-Ethiopia-Transport (LAPSSET) in Kenya. The question assumes that infrastructure projects such as the LAPSSET corridor inscribe not only particular ways of moving into a landscape but also one specific temporality that marginalises other future-making practices. The paper participates in the ongoing debate about how imagined futures and future-making practices can be appreciated and analysed methodologically. It thus contributes to the literature on geographies of the future by drawing together conceptual insights from anthropology, infrastructure studies, and critical cartography. Based on these different approaches, the paper proposes to regard future-making practices not only in relation to contentious timelines but also in terms of lines made by moving and drawing on landscapes and surfaces. Using a review of existing social foresight methods as a basis, we describe the practical implementation of CCC. Subsequently, the analysis of one collaboratively produced comic illustrates how the method can help to visualise ambivalent and uncertain imaginations of different futures that oppose the unitary vision of modernity produced by dominant infrastructural visions of a single future. We conclude by reflecting on possible ways of developing the method further.
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| 3. |
- Aalders, Johannes Theodor
(författare)
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Ghostlines: Movements, Anticipations, and Drawings of the LAPSSET Development Corridor in Kenya
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The Lamu Port-South Sudan-Ethiopia-Transport (LAPSSET) corridor is a partly completed development corridor in Kenya that will connect the eponymous places via roads, pipelines and railway lines, if completed. This thesis investigates how inhabitants of the traversed area navigate and shape the spatio-temporal landscape of the corridor, following three motifs: lines created through moving, anticipating, and drawing. Under moving, the thesis explores people’s encounters of LAPSSET as connection, obstacle, and repulsion, relying on mobile ethnography. In anticipating, the thesis introduces ‘spectral landscapes of anticipation’ to investigate different temporalities people create in relation to the corridor. In drawing, it considers ways of visualizing and envisioning infrastructure projects and introduces Collaborative Comic Creation as a possibility to cut through the visual normativity of infrastructural megaprojects.
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| 4. |
- Abad, C., et al.
(författare)
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On the 'Disclosure Initiative - Principles of Disclosure': The EAA Financial Reporting Standards Committee's View
- 2020
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Ingår i: Accounting in Europe. - : Informa UK Limited. - 1744-9480 .- 1744-9499. ; 17:1, s. 1-32
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Tidskriftsartikel (refereegranskat)abstract
- This paper summarises the contents of a comment letter produced by a working group of 12 academics in response to the International Accounting Standards Board (IASB) Discussion Paper on principles of disclosure. The comment letter was submitted by the Financial Reporting Standards Committee (FRSC) of the European Accounting Association (EAA). The work includes reviews of relevant academic literature of areas related to the various questions posed by the IASB in the Discussion Paper, including the 'disclosure problem' and the objective of the project, the suggested principles of effective communication, the roles of the primary financial statements and notes, the location of information and the use of performance measures. The paper also discusses the disclosure of accounting policies, the objectives of centralised disclosure, and the New Zealand Accounting Standards Board staff's approach to disclosure.
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| 5. |
- Abadpour, S., et al.
(författare)
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Inhibition of the prostaglandin D-2-GPR44/DP2 axis improves human islet survival and function
- 2020
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Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 0012-186X .- 1432-0428. ; 63, s. 1355-1367
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Tidskriftsartikel (refereegranskat)abstract
- Aims/hypothesis Inflammatory signals and increased prostaglandin synthesis play a role during the development of diabetes. The prostaglandin D-2 (PGD(2)) receptor, GPR44/DP2, is highly expressed in human islets and activation of the pathway results in impaired insulin secretion. The role of GPR44 activation on islet function and survival rate during chronic hyperglycaemic conditions is not known. In this study, we investigate GPR44 inhibition by using a selective GPR44 antagonist (AZ8154) in human islets both in vitro and in vivo in diabetic mice transplanted with human islets. Methods Human islets were exposed to PGD(2) or proinflammatory cytokines in vitro to investigate the effect of GPR44 inhibition on islet survival rate. In addition, the molecular mechanisms of GPR44 inhibition were investigated in human islets exposed to high concentrations of glucose (HG) and to IL-1 beta. For the in vivo part of the study, human islets were transplanted under the kidney capsule of immunodeficient diabetic mice and treated with 6, 60 or 100 mg/kg per day of a GPR44 antagonist starting from the transplantation day until day 4 (short-term study) or day 17 (long-term study) post transplantation. IVGTT was performed on mice at day 10 and day 15 post transplantation. After termination of the study, metabolic variables, circulating human proinflammatory cytokines, and hepatocyte growth factor (HGF) were analysed in the grafted human islets. Results PGD(2) or proinflammatory cytokines induced apoptosis in human islets whereas GPR44 inhibition reversed this effect. GPR44 inhibition antagonised the reduction in glucose-stimulated insulin secretion induced by HG and IL-1 beta in human islets. This was accompanied by activation of the Akt-glycogen synthase kinase 3 beta signalling pathway together with phosphorylation and inactivation of forkhead box O-1and upregulation of pancreatic and duodenal homeobox-1 and HGF. Administration of the GPR44 antagonist for up to 17 days to diabetic mice transplanted with a marginal number of human islets resulted in reduced fasting blood glucose and lower glucose excursions during IVGTT. Improved glucose regulation was supported by increased human C-peptide levels compared with the vehicle group at day 4 and throughout the treatment period. GPR44 inhibition reduced plasma levels of TNF-alpha and growth-regulated oncogene-alpha/chemokine (C-X-C motif) ligand 1 and increased the levels of HGF in human islets. Conclusions/interpretation Inhibition of GPR44 in human islets has the potential to improve islet function and survival rate under inflammatory and hyperglycaemic stress. This may have implications for better survival rate of islets following transplantation.
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| 6. |
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| 7. |
- Abd Alrahman, Yehia, 1986, et al.
(författare)
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Programming interactions in collective adaptive systems by relying on attribute-based communication
- 2020
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Ingår i: Science of Computer Programming. - : Elsevier BV. - 0167-6423. ; 192:June
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Tidskriftsartikel (refereegranskat)abstract
- © 2020 Elsevier B.V. Collective adaptive systems are new emerging computational systems consisting of a large number of interacting components and featuring complex behaviour. These systems are usually distributed, heterogeneous, decentralised and interdependent, and are operating in dynamic and possibly unpredictable environments. Finding ways to understand and design these systems and, most of all, to model the interactions of their components, is a difficult but important endeavour. In this article we propose a language-based approach for programming the interactions of collective-adaptive systems by relying on attribute-based communication; a paradigm that permits a group of partners to communicate by considering their run-time properties and capabilities. We introduce AbC, a foundational calculus for attribute-based communication and show how its linguistic primitives can be used to program a sophisticated variant of the well-known problem of Stable Allocation in Content Delivery Networks. In our variant, content providers are assigned to clients based on collaboration and by taking into account the preferences of both parties in a fully anonymous and distributed settings. We also illustrate the expressive power of attribute-based communication by showing the natural encoding of group-based, publish/subscribe-based and channel-based communication paradigms into AbC.
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| 8. |
- Abd Alrahman, Yehia, 1986, et al.
(författare)
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Reconfigurable Interaction for MAS Modelling
- 2020
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Ingår i: Proceedings of the 19th International Conference on Autonomous Agents and MultiAgent Systems. - Auckland, New Zealand : ACM. - 9781450375184
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Konferensbidrag (refereegranskat)abstract
- We propose a formalism to model and reason about multi-agent systems. We allow agents to interact and communicate in different modes so that they can pursue joint tasks; agents may dynamically synchronize, exchange data, adapt their behaviour, and reconfigure their communication interfaces. The formalism defines a local behaviour based on shared variables and a global one based on message passing. We extend LTL to be able to reason explicitly about the intentions of the different agents and their interaction protocols. We also study the complexity of satisfiability and model-checking of this extension.
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| 9. |
- Abdellah, Tebani, et al.
(författare)
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Integration of molecular profiles in a longitudinal wellness profiling cohort.
- 2020
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Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 11:1
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Tidskriftsartikel (refereegranskat)abstract
- An important aspect of precision medicine is to probe the stability in molecular profiles among healthy individuals over time. Here, we sample a longitudinal wellness cohort with 100 healthy individuals and analyze blood molecular profiles including proteomics, transcriptomics, lipidomics, metabolomics, autoantibodies andimmune cell profiling, complementedwith gut microbiota composition and routine clinical chemistry. Overall, our results show high variation between individuals across different molecular readouts, while the intra-individual baseline variation is low. The analyses show that each individual has a unique and stable plasma protein profile throughout the study period and that many individuals also show distinct profiles with regards to the other omics datasets, with strong underlying connections between the blood proteome and the clinical chemistry parameters. In conclusion, the results support an individual-based definition of health and show that comprehensive omics profiling in a longitudinal manner is a path forward for precision medicine.
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| 10. |
- Abdilzadeh, R., et al.
(författare)
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Molecular assessment of the distribution and taxonomy of the Lesser Whitethroat Sylvia curruca complex in Iran, with particular emphasis on the identity of the contentious taxon, zagrossiensis Sarudny, 1911
- 2020
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Ingår i: Journal of Ornithology. - : Springer Science and Business Media LLC. - 2193-7192 .- 2193-7206. ; 161, s. 665-676
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Tidskriftsartikel (refereegranskat)abstract
- The Lesser Whitethroat Sylvia curruca complex continues to provide challenges for ornithologists and taxonomists. One of the remaining outstanding questions concerns the taxonomic identity of the different breeding populations in Iran and in particular zagrossiensis, which inhabits the Zagros mountains. We here used the three mitochondrial genes cyt b, COI and ND2, to evaluate samples of the Lesser Whitethroat complex from Iran. Our data include predominantly samples from the breeding season, and we find evidence of three taxa from Iran, of which two are certainly breeding; althaea from Kopet Dagh in NE Iran and the Kerman mountains, east of the Zagros mountains, SE Iran; and curruca from central Zagros mountains and northwestern Iran. Three samples of halimodendri from the south of Iran were migrating or wintering birds. The taxonomically contentious population from the Zagros mountains is here identified as belonging to the curruca clade, and evidence to recognize zagrossiensis based on molecular data is deemed insufficient.
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