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- Aronsson, Mattias
(författare)
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Vilhelm Ekelund och den fransk-italienska kultursfären : Några nedslag i de tidiga prosaverken – från Antikt ideal (1909) till Attiskt i fågelperspektiv (1919)
- 2009
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Ingår i: Samlaren. - Uppsala : Svenska Litteratursällskapet. - 0348-6133 .- 2002-3871. ; 130, s. 85-101
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Tidskriftsartikel (refereegranskat)abstract
- The Swedish poet, essayist and aphorist Vilhelm Ekelund was not only influenced by German literature and philosophy, he also wrote extensive literary criticism on the subject of Romance language authors. This article discusses Ekelund’s relationship to some of the most influential French and Italian writers — as it can be seen in his work during the period 1909–1919. This relationship was ambiguous: he paid homage to French authors such as Montaigne, Montesquieu, Stendhal and Comte — as well as to the Italian poet and philosopher Leopardi – but he also severely criticized such distinguished writers as Baudelaire, Rousseau and Maupassant. One conclusion of this article is that the authors praised by Ekelund all venerate the Greek and Roman cultural heritage, whereas the despised novelists and poets were, in his opinion, either too “modern” or too “feminine” — both highly pejorative adjectives in the author’s terminology. It is also noted that Ekelund’s most ferocious attacks date from the first part of the decade, before he entered a more harmonic period with the works Metron (1918) and Attiskt i fågelperspektiv (1919).
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| 4. |
- Bennmarker, Helge, et al.
(författare)
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Do Benefit Hikes Damage Job Finding? Evidence from Swedish Unemployment Insurance Reforms
- 2005
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- In 2001 and 2002, Sweden introduced several unemployment insurance reforms. A major innovation in the first reform was the introduction of a two-tiered benefit structure for some unemployed individuals. This system involved supplementary compensation during the first 20 weeks of unemployment. The 2002 reform retained the two-tiered benefit structure but involved also substantial benefit hikes for spells exceeding 20 weeks. This paper examines how these reforms affected transitions from unemployment to employment. We take advantage of the fact that the reforms had quasi-experimental features where the “treatments” differed considerably among unemployed individuals. We find that the reforms had strikingly different effects on job finding among men and women. The two reforms in conjunction are estimated to have increased the expected duration of unemployment among men but to have decreased the duration of unemployment among women. The overall effect on the duration of unemployment is not statistically different from zero. However, the reforms reduced job finding among males who remained unemployed for more than 20 weeks.
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- Bergqvist, Tomas, 1962-, et al.
(författare)
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Upper secondary students’ task reasoning
- 2008
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Ingår i: International Journal of Mathematical Education in Science and Technology. - : Informa UK Limited. - 0020-739X .- 1464-5211. ; 39:1
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Tidskriftsartikel (refereegranskat)abstract
- Upper secondary students’ task solving reasoning was analysed, with a focus on grounds for different strategy choices and implementations. The results indicate that mathematically well-founded considerations were rare. The dominating reasoning types were algorithmic reasoning, where students tried to remember a suitable algorithm, sometimes in a random way, and guided reasoning, where progress was possible only when essentially all important strategy choices were made by the interviewer.
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- Björklund, Gunilla, 1973-
(författare)
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Driver Interaction : Informal Rules, Irritation and Aggressive Behaviour
- 2005
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- On a daily basis drivers have to share the roads with a great number of other road users. To make the driving task possible every driver has to take the intentions and behaviours of other road users into account. In other words, the road users have to interact with each other. The general aim of this thesis was to examine factors that regulate and influence the interaction between road users. To do so, three studies, applying a social psychological approach to driving, were conducted. In the first study it was investigated how the rules of priority, the design of the intersection, and the behaviour of other drivers influence yielding behaviour in intersections. The second study examined driver irritation and its relationship with aggressive behaviours. Finally, in the third study drivers’ attributions of their own and other drivers’ behaviour were investigated in relation to driver irritation. The thesis also includes a minor field study, aiming at examining to what extent informal traffic rules are used in intersections and in roundabouts, as well as measuring the validity of self-reports. The results indicate that, in addition to the formal rules, drivers rely on informal rules based on road design and on other drivers’ behaviour. Drivers also differ with respect to strategies of yielding behaviour. Irritability and aggressive behaviour on the roads appear largely to depend on drivers’ interactions and drivers’ interpretation of the behaviour of others. Some aggressive behaviour is an expression of irritation and may provoke irritation of other drivers. This means that an irritated driver might start a chain reaction, spreading irritation and aggressive behaviour from driver to driver. To diminish irritation and aggressive behaviour on the roads it is necessary to change drivers’ behaviour either by changing the road design or, which is probably a more possible remedy, by changing their general attitudes about driving. By providing drivers with insight into the cognitive biases they are subject to when judging other road users’ behaviour, both driver irritation and aggressive behaviours on the roads probably would decrease.
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- Blessborn, Daniel, et al.
(författare)
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A new approach to evaluate stability of amodiaquine and its metabolite in blood and plasma
- 2006
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Ingår i: Journal of Pharmaceutical and Biomedical Analysis. - : Elsevier BV. - 0731-7085 .- 1873-264X. ; 41:1, s. 207-212
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Tidskriftsartikel (refereegranskat)abstract
- A stability study for amodiaquine (AQ) and desethylamodiaquine (AQm) in whole blood and plasma is reported. AQ, AQm and chloroquine (CQ) were simultaneously analysed and the ratios AQ/CQ and AQm/CQ were used to ensure correct interpretation of the stability results. CQ was stable in whole blood and plasma at all tested temperatures enabling it to be a stability marker in stability studies. Simultaneous analysis of compounds, of which at least one is already known to be stable, permits a within sample ratio to be used as a stability indicator, The new approach significantly reduced bias when compared to the traditional approach. AQ and AQm were stable in plasma at -86 degrees C and -20 degrees C for 35 days, at 4 degrees C for 14 days and at 22 degrees C for 1 day. AQ and AQm were stable in blood at -86 degrees C and 4 degrees C for 35 days, at -20 degrees C and 22 degrees C for 7 days and at 37 degrees C for 1 day.
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| 8. |
- Blessborn, Daniel, et al.
(författare)
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Development and validation of an automated solid-phase extraction and liquid chromatographic method for determination of lumefantrine in capillary blood on sampling paper
- 2007
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Ingår i: Journal of Pharmaceutical and Biomedical Analysis. - : Elsevier BV. - 0731-7085 .- 1873-264X. ; 45:2, s. 282-287
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Tidskriftsartikel (refereegranskat)abstract
- A bioanalytical method for the determination of lumefantrine in 100 μl blood applied onto sampling paper, by solid-phase extraction and liquid chromatography, has been developed and validated. Whatman 31 ET Chr sampling paper was pre-treated with 0.75 M tartaric acid before sampling capillary blood to enable a high recovery of lumefantrine. Lumefantrine was extracted from the sampling paper, then further purified using solid-phase extraction and finally quantified with HPLC. The between-day variation was below 10% over the range 0.4-25 μM. The lower limit of quantification was 0.25 μM in 100 μl capillary blood. No decrease in lumefantrine concentration in dried blood spot is seen after 4 months storage at 22 °C. The method was also evaluated in field samples from patients in Tanzania after treatment with lumefantrine/artemether. Lumefantrine could be estimated accurately enough to assess bioavailability and treatment compliance on day 7 (i.e. 4 days after the last dose) after a standard regimen with the lumefantrine/artemether combination.
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| 9. |
- Blessborn, Daniel
(författare)
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Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. Automatic extraction procedures using a SPE robot were developed to reduce the workload for the analyst and to minimize variations in the extraction procedure. Liquid chromatography (LC) with either UV or mass spectrometric (MS) detection was used to determine sample concentrations. Determination of Pyronaridine in whole blood utilised a weak cation exchanger to extract Pyronaridine from blood. To improve LC separation between Pyronaridine and the internal standard, ion-pairing was utilized. For the simultaneous quantification of the highly lipophilic Atovaquone and the strong basic drug Proguanil with metabolites, a novel mixed mode solid phase extraction column was used. It combines the properties of a carboxylic acid (CBA) column and a non-polar octyl-silica (C8) column to extract the compounds from plasma; it also required a gradient LC separation. Stability is an important factor when developing new methods. A new approach was used to evaluate the stability of Amodiaquine in blood and plasma. This included the use of a stability marker, a stable compound which was added together with Amodiaquine when preparing the stability samples. This eliminated between-run variations and variations associated with preparation of new stock solutions. Lumefantrine (LF) is one of the active components in a new drug combination recommended by the World Health Organization as a replacement for older drugs which have lost their effect. The first of the two methods described for this compound is the determination of LF and a possible metabolite in plasma with a calibration range suitable for pharmacokinetic studies. In the second method, a capillary sampling technique is used where the blood is dried on a sampling paper and sent to the laboratory where the extraction and determination of LF concentrations take place. This method facilitates sample collection and will enable drug efficacy studies conducted in rural settings. To monitor a current change in treatment policy and self medication, a screening assay was developed. Its purpose is to be a complement to interviewing patients about their previous medication (in the previous few weeks) and to detect some of the more common drugs which might have been used.
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