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1.
  • A.O., Tillmar, et al. (författare)
  • Using X-chromosomal markers in relationship testing: : How to calculate likelihood ratios taking linkage and linkage disequilibrium into account
  • 2011
  • Ingår i: Forensic Science International : Genetics. - Elsevier. - 1872-4973. ; 5:5, s. 506-511
  • Tidskriftsartikel (refereegranskat)abstract
    • X-chromosomal markers in forensic genetics have become more widely used during the recent years, particularly for relationship testing. Linkage and linkage disequilibrium (LD) must typically be accounted for when using close X-chromosomal markers. Thus, when producing the weight-of-evidence, given by a DNA-analysis with markers that are linked, the normally used product rule is invalid. Here we present an efficient model for calculating likelihood ratio (LR) with markers on the X-chromosome which are linked and in LD. Furthermore, the model was applied on several cases based on data from the eight X-chromosomal loci included in the Mentype® Argus X-8 (Biotype). Using a simulation approach we showed that the use of X-chromosome data can offer valuable information for choosing between the alternatives in each of the cases we studied, and that the LR can be high in several cases. We demonstrated that when linkage and LD were disregarded, as opposed to taken into account, the difference in calculated LR could be considerable. When these differences were large, the estimated haplotype frequencies often had a strong impact and we present a method to estimate haplotype frequencies. Our conclusion is that linkage and LD should be accounted for when using the tested set of markers, and the presented model is an efficient way of doing so.
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2.
  • Aaboe, L, et al. (författare)
  • Incubator performance: an efficiency frontier analysis
  • 2008
  • Ingår i: International Journal of Business Innovation and Research. - 1751-0252. ; 2:4, s. 354-380
  • Tidskriftsartikel (refereegranskat)abstract
    • Assessments and evaluations of incubators has been a topic of discussion for as long as incubators have been in existence due to the fact that there has not been an agreement on how to determine good performance. This paper demonstrates the use of Data Envelopment Analysis (DEA) when studying performance of incubators. More specifically, it does so within the four dimensions of cooperation with universities, business networks, external funding and competence development on a sample of 16 Swedish incubators. We show that DEA enables us to measure non-numerical dimensions, and to simultaneously take into account the efforts made by both the incubator and the outcomes. Moreover, DEA provides benchmarks and, based on a model that divides the incubators into four different groups, illustrates the difference between the benchmark and the incubators' current situation.
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3.
  • Aaboen, Lise, 1978- (författare)
  • Business Incubators as Networks - How and Why?
  • 2008
  • Ingår i: Proceedings of ECEI 2008 The 3rd European Conference on Entrepreneurship and Innovation. - 978-1-906638-15-3 ; s. 1-8
  • Konferensbidrag (refereegranskat)
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8.
  • Aaboen, Lise, et al. (författare)
  • Nourishment for the piggy bank: facilitation of external financing in incubators
  • 2011
  • Ingår i: International Journal of Technology Transfer and Commercialisation (IJTTC). - 1470-6075. ; 10:3/4, s. 354-374
  • Tidskriftsartikel (refereegranskat)abstract
    • In this paper, we argue that incubators facilitate access to external financing for their incubatees. Incubators use a wide range of activities to facilitate the accessing of external financing from public and private sources. We have grouped these into two sets of activities. The general activities aim to develop the conditions for external financing through information, education of incubatees, network-building and lobbying activities. The specific activities aim to assist the individual incubatee in their pursuit of external finance through help in application procedures, establishing need for capital, making contacts with the best public or private investor, etc. Based on the survey data, we have also shown that it is more common for incubatees to attract external capital compared to non-incubator firms. The incubatees seem especially successful in attracting public capital. The incubatees also attract more private external capital, however, the observed frequency of private capital in the incubatees are low.
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