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Träfflista för sökning "WAKA:ref ;pers:(Lissner Lauren 1956);pers:(Lapidus Leif 1950)"

Sökning: WAKA:ref > Lissner Lauren 1956 > Lapidus Leif 1950

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  • Bengtsson, Calle, 1934-, et al. (författare)
  • [Time to stop basing the risk on BMI]
  • 2009
  • Ingår i: Läkartidningen. - 0023-7205. ; 106:26-27, s. 1752-3
  • Tidskriftsartikel (refereegranskat)
  • Kristjansson, Karl, 1958-, et al. (författare)
  • The interrelationships between fasting serum insulin level, obesity and blood pressure in women: Results from a cross-sectional population study of women in Gothenburg, Sweden
  • 1993
  • Ingår i: Hypertension Research. - 1348-4214. ; 16:3, s. 197-201
  • Tidskriftsartikel (refereegranskat)abstract
    • This study is based on a representative population sample of women in Gothenburg, Sweden. Three hundred and thirty-six 50-year-old nondiabetic women, not taking any antihypertensive medication, were included in the study. They underwent a comprehensive examination programme, where body weight, body height, waist and hip circumferences, systolic and diastolic blood pressures and fasting serum insulin concentration were measured. Fasting serum insulin concentration was significantly correlated with systolic and diastolic blood pressures. After controlling for both body mass index (BMI) and waist to hip circumference ratio (WHR), fasting serum insulin concentration remained independently associated with blood pressure (P=0.001 for systolic blood pressure, P=0.06 for diastolic blood pressure). When stratified for BMI or WHR the correlations between fasting serum insulin concentration and blood pressure remained significant only in the upper 50th precentiles of BMI and WHR. When relating pressure to different levels of fasting serum insulin concentration there seems to be a threshold at an insulin concentration corresponding to the upper quartile limit (at approximately 17?U/ml), above which level the blood pressure rises more obviously. The same phenomenon was seen for systolic and diastolic blood pressures.
  • Lapidus, Leif, 1950-, et al. (författare)
  • Weight and length at birth and their relationship to diabetes incidence and all-cause mortality--a 32-year follow-up of the population study of women in Gothenburg, Sweden
  • 2008
  • Ingår i: Primary Care Diabetes. ; 2, s. 127-133
  • Tidskriftsartikel (refereegranskat)abstract
    • Department of Primary Health Care, Göteborg University, Göteborg, Sweden. leif.lapidus@vgregion.se OBJECTIVE: The purpose of the study was to explore the relationship of weight and length at birth to diabetes in adult life and to all-cause mortality. Special attention was taken to potential confounding factors as age, family history, education, socio-economic group, physical inactivity, smoking, blood pressure, serum lipids and obesity. RESEARCH DESIGN AND METHODS: A longitudinal population study consisting of a representative sample of 1381 women aged 38-54 started in Gothenburg, Sweden, in 1968-1969 monitoring for diabetes mellitus and overall mortality over 32 years. Original delivery records were retrieved for 61.2% of the women. Death certificates were obtained for 99.3% the women who died during the 32-year follow-up period. RESULTS: We observed an inverse statistically significant relationship between birth weight and 32-year diabetes incidence independent of age, the highest incidence 16.3% in the lowest quartile of birth weight compared to 9.2% in the highest quartile. The relationship remained when controlling for the following covariates: education, socio-economic group, physical activity, smoking, systolic blood pressure, adult body mass index (BMI), waist-hip ratio, serum triglycerides and cholesterol. When overweight women (BMI> or =25) were excluded from the statistical analyses birth weight was even stronger related to the incidence of diabetes, 12.8% in lowest quartile and 5.7% in the highest quartile of birth weight independent of birth length, education, socio-economic group, physical activity, smoking, systolic blood pressure, body mass index, waist-hip ratio, blood glucose, serum triglycerides and cholesterol. Length at birth was a predictor for diabetes independent of age plus adult body mass index (BMI) and smoking but not independent of age only. No significant associations were observed between birth factors as birth weight and birth length and overall mortality during the 32-year of follow-up. CONCLUSIONS: A low birth weight seems to be a risk factor for diabetes in adult women independent of age and most of the established risk factors for diabetes.
  • Lissner, Lauren, 1956-, et al. (författare)
  • Diet, obesity and obesogenic trends in two generations of Swedish women.
  • 2008
  • Ingår i: European Journal of Nutrition. - 1436-6207. ; 48:8, s. 424-431
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: Secular trends in obesity and related lifestyle factors are reported in two generations of 38- and 50-year old Swedish women. Specifically, we describe changes in obesity and fat patterning, while examining concurrent shifts in factors that are proposed to be causally related to the modern obesity epidemic. METHODS: A total of 1,270 women aged 38 or 50 were selected from population registries and examined in 1968/69 (born 1930 or 1918) or 2004/05 (born 1966 or 1954). Anthropometric methods and lifestyle questions were unchanged between earlier and later surveys. Dietary comparisons were based on 24-h recall, with additional questions about usual alcohol and salt consumption patterns. In subgroups, 24-h urinary sodium was determined. RESULTS: Weight, height, waist circumference, waist-hip ratio, triceps and subscapular skinfold measures were all significantly higher in later-born cohorts, although BMI and obesity were not significantly changed. Higher sodium excretion was observed among later-born sub-groups, consistent with reports of increasing salt preference. Lower proportions of energy as fat and sucrose, but higher carbohydrate, protein and fiber concentrations were reported by later-born cohorts. There were shifts towards increased frequency of wine and liquor consumption, but decreased beer. Leisure time physical activity and perceived stress levels both increased significantly over 36 years. CONCLUSIONS: A number of anthropometric and lifestyle differences between two generations of Swedish women were observed. Increases in subcutaneous and abdominal fatness were detected without significantly increasing BMI. While some aspects of diet showed improvement, increases in salt preference and sodium excretion are cause for concern.
  • Lissner, Lauren, 1956-, et al. (författare)
  • Fasting insulin in relation to subsequent blood pressure changes and hypertension in women
  • 1992
  • Ingår i: Hypertension. ; 20, s. 797-801
  • Tidskriftsartikel (refereegranskat)abstract
    • Department of Primary Health Care, University of Göteborg, Sweden. The role of hyperinsulinemia in the development of hypertension is not well understood, particularly insofar as both conditions relate to obesity. The present analysis examines the hypothesis that hyperinsulinemia, independent of obesity, precedes hypertension and natural blood pressure increases in women. The subjects were 50-year-old women from a prospective population study in Gothenburg, Sweden. Fasting insulin levels were determined at baseline (1968-1969) and were evaluated in relation to subsequent hypertension. Blood pressures were measured at the initial physical examination and at the 6- and 12-year follow-up examinations. The first analysis presented here (n = 278) identified incident cases of hypertension during the 12-year follow-up period, whereas the second analysis (n = 219) examined continuous changes in blood pressure. In both analyses, degree, type, and changes in obesity were considered as possible confounding factors. High fasting insulin values were predictive of subsequent incidence of hypertension over the 12-year follow-up period. Subjects with insulin values above the 75th percentile experienced three times more hypertension than did those below the 25th percentile. There was also a significant association between insulin at baseline and increases in diastolic (but not systolic) blood pressure. The positive relations between fasting insulin, on one hand, and diastolic blood pressure changes and hypertension, on the other, could not be explained by confounding effects of body mass index, waist/hip ratio, or weight gain. These findings are consistent with the hypothesis that fasting insulin levels may be one predisposing factor in the etiology of hypertension.
  • Rowshan Ravan, Andisheh, et al. (författare)
  • Thirty-six-year secular trends in sleep duration and sleep satisfaction, and associations with mental stress and socioeconomic factors - results of the Population Study of Women in Gothenburg, Sweden
  • 2010
  • Ingår i: Journal of Sleep Research. - 1365-2869. ; 19:3, s. 496-503
  • Tidskriftsartikel (refereegranskat)abstract
    • Several European studies have reported sleeping problems in 20-40% of the population. We used data from the Population Study of Women in Gothenburg, based on medical examinations of three different representative cohorts of 38- and 50-year-old women in 1968-1969, 1980-1981 and 2004-2005 to study secular trends in sleep-related factors. The average reported sleep duration declined by about 15 min in the 38-year-old women during the 36 years of observation. No corresponding change in sleep duration was observed among 50-year-old women. During the same period, the proportion of women complaining of sleeping problems almost doubled in both age groups: from 17.7% in 1968 to 31.7% in 2004 in 38-year-old women, and from 21.6% to 41.8% in 50-year-old women. The prevalence of insomnia was higher in 50-year olds than in 38-year olds in all investigated cohorts. The use of sleeping medications remained unchanged since 1968. There were significant associations between perceived sleeping problems and reported lower satisfaction concerning economic, social and family situations, as well as with medical retirement and mental stress. There was, however, no association between alcohol consumption and sleeping problems. Regular leisure time physical activity was not, in most cases, associated with less perceived sleeping problems. Our study indicates that the physician should take socio-economic and family situations into consideration when examining female patients complaining of sleeping problems. Improvements on society level rather than on the individual level could be expected to be more efficient in improving women's sleep.
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