Sökning: WFRF:(Alving Kjell 1959 )
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High levels of phys...
High levels of physical activity are associated with poorer asthma control in young females but not in males
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- Lövström, Ludvig (författare)
- Uppsala universitet,Klinisk fysiologi
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- Emtner, Margareta (författare)
- Uppsala universitet,Fysioterapi,Lungmedicin och allergologi,Lungmedicin och allergologi, Respiratory Medicine and Allergology
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- Alving, Kjell, 1959- (författare)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Pediatrisk inflammationsforskning/Alving
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- Nordvall, Lennart (författare)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Pediatrisk inflammationsforskning/Alving
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- Borres, Magnus P, 1956- (författare)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Pediatrisk inflammationsforskning/Alving
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- Janson, Christer (författare)
- Uppsala universitet,Lungmedicin och allergologi
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- Malinovschi, Andrei (författare)
- Uppsala universitet,Klinisk fysiologi
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(creator_code:org_t)
- 2015-11-19
- 2016
- Engelska.
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Ingår i: Respirology (Carlton South. Print). - : Wiley. - 1323-7799 .- 1440-1843. ; 21:1, s. 79-87
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND AND OBJECTIVE: Earlier studies on the levels of physical activity in asthma patients compared with controls have yielded varying results. We have previously reported that high versus moderate levels of physical activity were associated with higher prevalence of wheezing, especially in females. Here we studied the levels of physical activity in young patients with asthma and healthy subjects and their effect on asthma control.METHODS: Four hundred eight physician-diagnosed patients with asthma and 118 controls (10-34 years) answered questions concerning frequency and/or duration of physical activity and undertook the Asthma Control Test (ACT), spirometry, methacholine challenges and exhaled nitric oxide measurements.RESULTS: Asthma patients were more frequently physically active (P = 0.01) and for longer durations (P = 0.002) than controls. Highly versus moderately physically active patients with asthma had a higher prevalence of not well-controlled asthma (ACT < 20) when physical activity was assessed by frequency (40.6% vs 24.1%, P = 0.001) or duration (39.0% vs 21.7%, P < 0.001). This was only seen in females who had reduced ACT items (P < 0.05). Frequently versus moderately active females had an odds ratio of 4.81 (2.43, 9.51) to have ACT < 20, while no such effect was found in males (OR 1.18 (0.61, 2.30)) and this interaction was statistically significantly associated with gender (P = 0.003). No differences in fraction of exhaled nitric oxide or methacholine reactivity were found between moderately and highly physically active females with asthma.CONCLUSION: Young asthma patients were more active than controls. High levels of physical activity were associated with poor asthma control as judged by the ACT in females, but not in males, and this appears unrelated to airway inflammation or responsiveness.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- airway responsiveness; asthma control; exhaled nitric oxide; gender difference; physical activity
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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