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Träfflista för sökning "WFRF:(Andersson Carina) ;pers:(Johansson Carina)"

Sökning: WFRF:(Andersson Carina) > Johansson Carina

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1.
  • Andersson, Gerhard, et al. (författare)
  • Chronic Pain in Older Adults: A Controlled Pilot Trial of a Brief Cognitive-Behavioural Group Treatment
  • 2012
  • Ingår i: Behavioural and Cognitive Psychotherapy. - : Cambridge University Press (CUP). - 1352-4658 .- 1469-1833. ; 40:2, s. 239-244
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Chronic pain is a common condition among older adults. While cognitive behaviour therapy (CBT) has been tested in numerous studies on adults and children there are fewer studies on older persons. The objective of this study was to investigate the effects of a six-session CBT group treatment for older persons with chronic pain. As a secondary aim we investigated whether treatment credibility was associated with outcome. Method: We included 21 persons (mean age = 72.0 years) who were randomly allocated to either a waitlist condition or treatment consisting of applied relaxation, with the addition of problem solving, assertiveness, communication strategies, sleep management, and relapse prevention. Results: Few statistically significant effects were found on measures of pain, mood, anxiety, and quality of life; however, a significant treatment effect with a between group effect size of d = 1.0 was observed with respect to perceived ability to function despite the discomfort of pain. Conclusion: The study provides some preliminary support for the use of group-based CBT with a focus on applied relaxation for older adults with chronic pain.
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2.
  • Andersson, Rina Argelia, et al. (författare)
  • Organic matter delivery to Quaternary sediments of Amundsen Basin, central Arctic Ocean
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Quaternary marine sediments retrieved from the central Arctic Ocean in a 30 cm long core, were analyzed for paleoenvironmental reconstruction. n-Alkane biomarkers combined with elemental analyses that include X-ray fluorescence (XRF) core scanning provide complementary information that suggest important influxes of terrigenous derived organic matter (OM) with depth. Changes in the variability of n-alkane-derived and elemental ratios with depth reflect the complexity of the organic carbon cycle in this region. The distributions and abundances of the long-chain n-alkanes reveal a high content of terrigenous derived components and suggest together with mathematical estimations high deliveries of the terrigenous OM in the past. XRF trace metal analyses suggest less-oxygenated bottom waters that may have allowed for better preservation conditions of OM deeper in the core.
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3.
  • Barkarmo, Sargon, et al. (författare)
  • Enhanced bone healing around nanohydroxyapatite-coated polyetheretherketone implants : An experimental study in rabbit bone
  • 2014
  • Ingår i: Journal of biomaterials applications. - : Sage Publications. - 0885-3282 .- 1530-8022. ; 29:5, s. 737-747
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To investigate the bone response to threaded polyetheretherketone (PEEK) implants coated with nanohydroxyapatite. Materials and methods: A total of 39 PEEK implants were coated with nanocrystalline hydroxyapatite and 39 uncoated implants were used as controls. The implant surface was characterized by optical interferometry and scanning electron microscope. The implants were inserted in the tibia and femur of 13 rabbits. After 6 weeks of healing, quantitative and qualitative analyses were performed. Results: The test implants showed significantly higher removal torque test values compared with the control group. Histomorphometric evaluation demonstrated higher bone-to-implant contact for the test implants; however, there were no differences in bone area between the groups. Qualitative histological analyses demonstrated inflammatory cellular reactions in close vicinity of both implant surfaces. A two-cell layer of foreign body giant cells was observed irrespective of sample type. Conclusion: Our findings demonstrate that implants with a threaded design render good stability to PEEK in both coated and uncoated implants. Nanohydroxyapatite-coated PEEK implants demonstrated improved bone formation compared with uncoated controls.
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4.
  • Barnes, Brian R, et al. (författare)
  • The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle
  • 2004
  • Ingår i: Journal of Biological Chemistry. - 0021-9258 .- 1083-351X. ; 279:37, s. 38441-38447
  • Tidskriftsartikel (refereegranskat)abstract
    • 5'-AMP-activated protein kinase (AMPK) is a metabolic stress sensor present in all eukaryotes. A dominant missense mutation (R225Q) in pig PRKAG3, encoding the muscle-specific gamma3 isoform, causes a marked increase in glycogen content. To determine the functional role of the AMPK gamma3 isoform, we generated transgenic mice with skeletal muscle-specific expression of wild type or mutant (225Q) mouse gamma3 as well as Prkag3 knockout mice. Glycogen resynthesis after exercise was impaired in AMPK gamma3 knock-out mice and markedly enhanced in transgenic mutant mice. An AMPK activator failed to increase skeletal muscle glucose uptake in AMPK gamma3 knock-out mice, whereas contraction effects were preserved. When placed on a high fat diet, transgenic mutant mice but not knock-out mice were protected against excessive triglyceride accumulation and insulin resistance in skeletal muscle. Transfection experiments reveal the R225Q mutation is associated with higher basal AMPK activity and diminished AMP dependence. Our results validate the muscle-specific AMPK gamma3 isoform as a therapeutic target for prevention and treatment of insulin resistance.
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  • Resultat 1-5 av 5

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