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Sökning: WFRF:(Andersson JLR)

  • Resultat 1-10 av 29
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  • Fischer, H, et al. (författare)
  • Fear conditioning and brain activity : a positron emission tomography study in humans.
  • 2000
  • Ingår i: Behav Neurosci. - 0735-7044. ; 114:4, s. 671-80
  • Tidskriftsartikel (övrigt vetenskapligt)abstract
    • Regional cerebral blood flow (rCBF) was measured with H2 (15)O positron emission tomography in 8 healthy women before and after fear conditioning (i.e., paired shocks) and unpaired shocks to videotape cues. Conditioning was supported by enhanced peripheral nervous system recordings and subjective ratings. Fear conditioning increased rCBF in the central gray of the midbrain; bilaterally in the hypothalamus, the thalamus, and the left striatum; and in the right and left anterior cingulate and right prefrontal cortices. Regional CBF was attenuated bilaterally in the right and left prefrontal, temporal (including the amygdala), parietal, and occipital cortices, and in the left orbitofrontal cortex. When compared with unpaired shock presentations, fear conditioning resulted in elevated rCBF in the left cerebellum. Hence, in the present paradigm, only neural activity in the left cerebellum solely reflected processes associated with true Pavlovian conditioning.
  • Fischer, Hakan, et al. (författare)
  • Right-sided human prefrontal brain activation during acquisition of conditioned fear.
  • 2002
  • Ingår i: Emotion. - 1528-3542. ; 2:3, s. 233-41
  • Tidskriftsartikel (refereegranskat)abstract
    • This H2(15)O positron emission tomography (PET) study reports on relative regional cerebral blood flow (rCBF) alterations during fear conditioning in humans. In the PET scanner, subjects viewed a TV screen with either visual white noise or snake videotapes displayed alone, then with electric shocks, followed by final presentations of white noise and snakes. Autonomic nervous system responses confirmed fear conditioning only to snakes. To reveal neural activation during acquisition, while equating sensory stimulation, scans during snakes with shocks and white noise alone were contrasted against white noise with shocks and snakes alone. During acquisition, rCBF increased in the right medial frontal gyrus, supporting a role for the prefrontal cortex in fear conditioning to unmasked evolutionary fear-relevant stimuli.
  • Padilla, Nelly, et al. (författare)
  • Breakdown of Whole-brain Dynamics in Preterm-born Children
  • 2020
  • Ingår i: Cerebral Cortex. - : Oxford University Press. - 1047-3211. ; 30:3, s. 1159-1170
  • Tidskriftsartikel (refereegranskat)abstract
    • The brain operates at a critical point that is balanced between order and disorder. Even during rest, unstable periods of random behavior are interspersed with stable periods of balanced activity patterns that support optimal information processing. Being born preterm may cause deviations from this normal pattern of development. We compared 33 extremely preterm (EPT) children born at < 27 weeks of gestation and 28 full-term controls. Two approaches were adopted in both groups, when they were 10 years of age, using structural and functional brain magnetic resonance imaging data. The first was using a novel intrinsic ignition analysis to study the ability of the areas of the brain to propagate neural activity. The second was a whole-brain Hopf model, to define the level of stability, desynchronization, or criticality of the brain. EPT-born children exhibited fewer intrinsic ignition events than controls; nodes were related to less sophisticated aspects of cognitive control, and there was a different hierarchy pattern in the propagation of information and suboptimal synchronicity and criticality. The largest differences were found in brain nodes belonging to the rich-club architecture. These results provide important insights into the neural substrates underlying brain reorganization and neurodevelopmental impairments related to prematurity.
  • ANDERSSON, JLR, et al. (författare)
  • 1995
  • Ingår i: JOURNAL OF NUCLEAR MEDICINE. - : SOC NUCLEAR MEDICINE INC. - 0161-5505. ; 36:7, s. 1307-1315
  • Tidskriftsartikel (övrigt vetenskapligt)abstract
    • Combining MRI morphological data with functional PET data offers significant advantages in research as well as in many clinical situations. Automatic methods are needed, however, to coregister the data from the two modalities. Methods: Simulated PET imag
  • Andersson, JLR, et al. (författare)
  • A multivariate approach to registration of dissimilar tomographic images
  • 1999
  • Ingår i: European Journal of Nuclear Medicine. - : SPRINGER VERLAG. - 0340-6997 .- 1432-105X. ; 26:7, s. 718-733
  • Tidskriftsartikel (refereegranskat)abstract
    • We devised a method to allow for retrospective registration of tomographic images with very different information content, the main emphasis being on sets of positron emission tomography images obtained with different tracers. A multivariate cost-function
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  • Resultat 1-10 av 29
  • [1]23Nästa

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