| 1. |
- Andersson Lundell, Anna-Carin, 1976, et al.
(författare)
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Development of gut-homing receptors on circulating B cells during infancy.
- 2011
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Ingår i: Clinical immunology. - : Elsevier BV. - 1521-7035 .- 1521-6616. ; 138:1, s. 97-106
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Tidskriftsartikel (refereegranskat)abstract
- B cell gut-homing is mainly mediated by α4β7, CCR9 and CCR10. We here studied the expression of these receptors on B cells from cord blood and from peripheral blood at 1, 4, 18 and 36months of age in a prospective cohort of Swedish infants. The proportion of all B cells expressing α4β7 as well as the fraction of CCR10+ B cells expressing α4β7 was highest in early infancy. Nearly all naïve B cells in all age groups expressed α4β7, whereas the expression on class-switched B cells decreased with age. Moreover, the proportion of both IgA+ and IgG+ B cells expressing α4β7, CCR9 and CCR10 were higher during the first months when compared to adults. In conclusion, the high fraction of circulating IgA+ and IgG+ B cells expressing CCR9 and CCR10 in the first months of life indicates activation of naïve B cells in the gut, coinciding with bacterial colonization.
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| 2. |
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| 3. |
- Neitzel, R. L., et al.
(författare)
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Comparison of Multiple Measures of Noise Exposure in Paper Mills
- 2016
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Ingår i: Annals of Occupational Hygiene. - : Oxford University Press (OUP). - 0003-4878 .- 1475-3162. ; 60:5, s. 581-596
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Tidskriftsartikel (refereegranskat)abstract
- Noise exposures are associated with a host of adverse health effects, yet these exposures remain inadequately characterized in many industrial operations, including paper mills. We assessed noise at four paper mills using three measures: (i) personal noise dosimetry, (ii) area noise measurements, and (iii) questionnaire items addressing several different aspects of perceived noise exposure. We assessed exposures to noise characterized using the three measures and compared the relationships between them. We also estimated the validity of each of the three measures using a novel application of the Method of Triads, which does not appear to have been used previously in the occupational health literature. We collected 209 valid dosimetry measurements and collected perceived noise exposure survey items from 170 workers, along with 100 area measurements. We identified exposures in excess of 85 dBA at all mills. The dosimetry and area noise measurements assigned to individual subjects generally showed good agreement, but for some operations within mill, large differences between the two measures were observed, and a substantial fraction of paired measures differed by > 5 dB. Perceived noise exposures varied greatly between the mills, particularly for an item related to difficulty speaking in noise. One perceived noise exposure item related to difficulty hearing due to noise showed strong and significant correlations with both dosimetry and area measurements. The Method of Triads analysis showed that dosimetry measures had the highest estimated validity coefficient (0.70), and that the best performing perceived exposure measure had validity that exceeded that of area measurements (0.48 versus 0.40, respectively). Workers in Swedish pulp mills have the potential for exposures to high levels of noise. Our results suggest that, while dosimetry remains the preferred approach to exposure assessment, perceived noise exposures can be used to evaluate potential exposures to noise in epidemiological studies.
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| 4. |
- Neitzel, R. L., et al.
(författare)
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Development of a Job Exposure Matrix for Noise in the Swedish Soft Tissue Paper Industry
- 2018
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Ingår i: Annals of Work Exposures and Health. - : Oxford University Press (OUP). - 2398-7308 .- 2398-7316. ; 62:2, s. 195-209
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Noise exposure is a common occupational hazard, but has not been sufficiently characterized in paper mills. We developed a job-exposure matrix (JEM) for noise exposure for use in estimating exposures among Swedish soft tissue paper mill workers.& para;& para;Methods: We used a combination of area and personal dosimetry noise exposure measurements made at four soft tissue paper mills by industry and research staff between 1977 and 2013 to estimate noise exposures by department, location, and job title. We then utilized these estimates, in conjunction with information on process and facility changes and use of hearing protection collected via focus groups, to create a seven-category, semi-quantitative JEM for all departments, locations, and job titles spanning the years 1940-2010.& para;& para;Results: The results of the 1157 area and personal dosimetry noise measurements indicated that noise levels have generally declined in Swedish paper mills over time, though these changes have been neither uniform nor monotonic within or across the four mills. Focus group results indicated that use of hearing protection has generally increased over time. The noise JEM totals 1917 cells, with each cell representing a unique combination of operation, job title, and single year. We estimated that -50% of workers at the four mills assessed were exposed at or above the Swedish 8-h average noise exposure limit of an 85 dBA at the conclusion of the study period in 2010.& para;& para;Conclusions: Our results highlight the continuing need for hearing loss prevention and noise control efforts at these and similar mills, and the completed JEM now represents a tool for use in epidemiological studies of noise-related health outcomes.
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| 5. |
- Olin, Anna-Carin, 1960, et al.
(författare)
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Prevalence of asthma and exhaled nitric oxide are increased in bleachery workers exposed to ozone.
- 2004
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Ingår i: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. - 0903-1936. ; 23:1, s. 87-92
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Tidskriftsartikel (refereegranskat)abstract
- The aims of the present study were to determine whether exposure to high peaks of ozone resulted in an increased prevalence of asthma or respiratory symptoms among bleachery workers and whether nitric oxide (NO) was elevated in the exhaled air of these workers. Bleachery workers (n=228) from three Swedish pulp mills who had been exposed to ozone, together with 63 unexposed control subjects, were investigated by means of spirometry, Phadiatop, exhaled and nasal NO and answers to a questionnaire concerning respiratory symptoms and exposure. Exposure to an ozone peak that gave rise to respiratory symptoms was defined as a "gassing". Bleachery workers reporting four or more gassings involving ozone had an increased prevalence of adult-onset asthma, wheeze, and current asthma symptoms. They also had a higher median concentration of exhaled NO in comparison with those who reported no such gassings (19.2 versus 15.7 parts per billion). No such associations were found in respect of nasal NO. The results from this study show that bleachery workers who have been repeatedly exposed to ozone gassings have an increased prevalence of adult-onset asthma. The results also indicate exhaled nitric oxide may be a marker of airway inflammation in bleachery workers who have been exposed to high peaks of ozone.
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| 6. |
- Andersson, Marianne, 1955-
(författare)
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Faktasökning
- 2010. - 4
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Ingår i: Att studera Afrika. - Uppsala : Nordiska Afrikainstitutet. - 9789171066725 ; , s. 16-23
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Bokkapitel (populärvet., debatt m.m.)
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| 7. |
- Andersson, Marianne, 1955-
(författare)
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Literature searching
- 2011. - 2
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Ingår i: Studying Africa. - Uppsala : Nordiska Afrikainstitutet. - 9789171066862 ; , s. 7-15
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Bokkapitel (populärvet., debatt m.m.)
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| 8. |
- Andersson, Marianne, 1955-
(författare)
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Literature searching and searching for facts
- 2014. - 3
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Ingår i: Studying Africa. - Uppsala : Nordiska Afrikainstitutet. - 9789171067500 ; , s. 7-22
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Bokkapitel (populärvet., debatt m.m.)
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| 9. |
- Andersson, Marianne, 1955-
(författare)
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Litteratursökning
- 2010. - 4
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Ingår i: Att studera Afrika. - Uppsala : Nordiska Afrikainstitutet. - 9789171066725 ; , s. 7-15
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Bokkapitel (populärvet., debatt m.m.)
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| 10. |
- Andersson, Marianne, 1955-
(författare)
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Searching for facts
- 2011. - 2
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Ingår i: Studying Africa. - Uppsala : Nordiska Afrikainstitutet. - 9789171066862 ; , s. 16-23
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Bokkapitel (populärvet., debatt m.m.)
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