| 1. |
- Bauer, M., et al.
(författare)
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Solar insolation in springtime influences age of onset of bipolar I disorder
- 2017
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Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 136:6, s. 571-582
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Forskningsöversikt (refereegranskat)abstract
- Objective: To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder. Method: Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth-cohort, family history, polarity of first episode and country physician density. Results: There was a significant, inverse association between the maximum monthly increase in solar insolation at the onset location, and the age of onset. This effect was reduced in those without a family history of mood disorders and with a first episode of mania rather than depression. The maximum monthly increase occurred in springtime. The youngest birth-cohort had the youngest age of onset. All prior relationships were confirmed using both the entire sample, and only the youngest birth-cohort (all estimated coefficients P < 0.001). Conclusion: A large increase in springtime solar insolation may impact the onset of bipolar disorder, especially with a family history of mood disorders. Recent societal changes that affect light exposure (LED lighting, mobile devices backlit with LEDs) may influence adaptability to a springtime circadian challenge.
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| 2. |
- Bauer, Michael, et al.
(författare)
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Association between solar insolation and a history of suicide attempts in bipolar I disorder.
- 2019
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Ingår i: Journal of psychiatric research. - : Elsevier BV. - 1879-1379 .- 0022-3956. ; 113, s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- In many international studies, rates of completed suicide and suicide attempts have a seasonal pattern that peaks in spring or summer. This exploratory study investigated the association between solar insolation and a history of suicide attempt in patients with bipolar I disorder. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area on Earth. Data were collected previously from 5536 patients with bipolar I disorder at 50 collection sites in 32 countries at a wide range of latitudes in both hemispheres. Suicide related data were available for 3365 patients from 310 onset locations in 51 countries. 1047 (31.1%) had a history of suicide attempt. There was a significant inverse association between a history of suicide attempt and the ratio of mean winter solar insolation/mean summer solar insolation. This ratio is smallest near the poles where the winter insolation is very small compared to the summer insolation. This ratio is largest near the equator where there is relatively little variation in the insolation over the year. Other variables in the model that were positively associated with suicide attempt were being female, a history of alcohol or substance abuse, and being in a younger birth cohort. Living in a country with a state-sponsored religion decreased the association. (All estimated coefficients p < 0.01). In summary, living in locations with large changes in solar insolation between winter and summer may be associated with increased suicide attempts in patients with bipolar disorder. Further investigation of the impacts of solar insolation on the course of bipolar disorder is needed.
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| 3. |
- Oieroset, M., et al.
(författare)
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Reconnection With Magnetic Flux Pileup at the Interface of Converging ts at the Magnetopause
- 2019
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Ingår i: Geophysical Research Letters. - : American Geophysical Union (AGU). - 0094-8276 .- 1944-8007. ; 46:4, s. 1937-1946
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Tidskriftsartikel (refereegranskat)abstract
- We report Magnetospheric Multiscale observations of reconnection in a in current sheet at the interface of interlinked flux tubes carried by nverging reconnection jets at Earth's magnetopause. The ion skin pth-scale width of the interface current sheet and the non-frozen-in ns indicate that Magnetospheric Multiscale crossed the reconnection yer near the X-line, through the ion diffusion region. Significant leup of the reconnecting component of the magnetic field in this and ree other events on approach to the interface current sheet was companied by an increase in magnetic shear and decrease in , leading conditions favorable for reconnection at the interface current sheet. e pileup also led to enhanced available magnetic energy per particle d strong electron heating. The observations shed light on the olution and energy release in 3-D systems with multiple reconnection tes. ain Language Summary The Earth and the solar wind magnetic fields terconnect through a process called magnetic reconnection. The newly connected magnetic field lines are strongly bent and accelerate rticles, similar to a rubber band in a slingshot. In this paper we ve used observations from NASA's Magnetospheric MultiScale spacecraft investigate what happens when two of these slingshot-like magnetic eld lines move toward each other and get tangled up. We found that the o bent magnetic field lines tend to orient themselves perpendicular to ch other as they become interlinked and stretched, similar to what bber bands would do. This reorientation allows the interlinked gnetic fields to reconnect again, releasing part of the built-up gnetic energy as strong electron heating. The results are important cause they show how interlinked magnetic fields, which occur in many lar and astrophysics contexts, reconnect and produce enhanced electron ating, something that was not understood before.
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| 4. |
- Angelopoulos, Konstantinos, et al.
(författare)
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Model predictive control for software systems with CobRA
- 2016
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Ingår i: Proceedings - 11th International Symposium on Software Engineering for Adaptive and Self-Managing Systems, SEAMS 2016. - New York, NY, USA : ACM. - 9781450341875 ; , s. 35-46
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Konferensbidrag (refereegranskat)abstract
- Self-adaptive software systems monitor their operation and adapt when their requirements fail due to unexpected phenomena in their environment. This paper examines the case where the environment changes dynamically over time and the chosen adaptation has to take into account such changes. In control theory, this type of adaptation is known as Model Predictive Control and comes with a well-developed theory and myriads of successful applications. The paper focuses on modelling the dynamic relationship between requirements and possible adaptations. It then proposes a controller that exploits this relationship to optimize the satisfaction of requirements relative to a cost-function. This is accomplished through a model-based framework for designing self-adaptive software systems that can guarantee a certain level of requirements satisfaction over time, by dynamically composing adaptation strategies when necessary. The proposed framework is illustrated and evaluated through a simulation of the Meeting-Scheduling System exemplar.
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| 5. |
- Artemyev, A. V., et al.
(författare)
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Field-Aligned Currents Originating From the Magnetic Reconnection Region : Conjugate MMS-ARTEMIS Observations
- 2018
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Ingår i: Geophysical Research Letters. - : American Geophysical Union (AGU). - 0094-8276 .- 1944-8007. ; 45:12, s. 5836-5844
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Tidskriftsartikel (refereegranskat)abstract
- Near-Earth magnetic reconnection reconfigures the magnetotail and produces strong plasma flows that transport plasma sheet particles and electromagnetic energy to the inner magnetosphere. An essential element of such a reconfiguration is strong, transient field-aligned currents. These currents, believed to be generated within the plasma sheet and closed at the ionosphere, are responsible for magnetosphere-ionosphere coupling during substorms. We use conjugate measurements from Magnetospheric Multiscale (MMS) at the plasma sheet boundary (around x approximate to- 10R(E)) and Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun (ARTEMIS) at the equator (around x approximate to- 60R(E)) to explore the potential generation region of these currents. We find a clear correlation between the field-aligned current intensity measured by MMS and the tailward plasma sheet flows measured by ARTEMIS. To better understand the origin of this correlation, we compare spacecraft observations with results from 3-D particle-in-cell simulations of magnetotail reconnection. The comparison reveals that field-aligned currents and plasma flows start, wax, and wane due to the development of a reconnection region between MMS (near-Earth) and ARTEMIS (at lunar distance). A weak correlation between the field-aligned current intensity at MMS and earthward flow magnitudes at ARTEMIS suggests that distant magnetotail reconnection does not significantly contribute to the generation of the observed near-Earth currents. Our findings support the idea that the dominant role of the near-Earth magnetotail reconnection in the field-aligned current generation is likely responsible for their transient nature, whereas more steady distant tail reconnection would support long-term field-aligned current system. Plain Language Summary Field-aligned currents connect the Earth magnetotail and ionosphere, proving energy and information transport from the region where main energy release process, magnetic reconnection, occurs to the region where the collisional energy dissipation takes place. Therefore, investigation and modeling of the field-aligned current generation is important problem of the magnetosphere plasma physics. However, field-aligned current investigation requires simultaneous observations of reconnection signatures in the magnetotail and at high latitudes. Simultaneous and conjugate operation of two multispacecraft missions, Magnetospheric Multiscale and Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun, for the first time provide an opportunity for such investigation. Combining spacecraft observations with results from 3-D particle-in-cell simulations of magnetotail reconnection, we demonstrate that field-aligned currents and plasma flows start, wax, and wane due to the development of a reconnection region between near-Earth (Magnetospheric Multiscale location) and lunar distant tail (Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun location). Our findings support the idea that the dominant role of the near-Earth magnetotail reconnection in the field-aligned current generation is likely responsible for their transient nature, whereas more steady distant tail reconnection would support long-term field-aligned current system.
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| 6. |
- Konstantinos, Angelopoulos, et al.
(författare)
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Engineering Self-Adaptive Software Systems : From Requirements to Model Predictive Control
- 2018
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Ingår i: ACM Transactions on Autonomous and Adaptive Systems. - : Association for Computing Machinery (ACM). - 1556-4665 .- 1556-4703. ; 13:1
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Tidskriftsartikel (refereegranskat)abstract
- Self-adaptive software systems monitor their operation and adapt when their requirements fail due to unexpected phenomena in their environment. This article examines the case where the environment changes dynamically over time and the chosen adaptation has to take into account such changes. In control theory, this type of adaptation is known as Model Predictive Control and comes with a well-developed theory and myriad successful applications. The article focuses on modeling the dynamic relationship between requirements and possible adaptations. It then proposes a controller that exploits this relationship to optimize the satisfaction of requirements relative to a cost function. This is accomplished through a model-based framework for designing self-adaptive software systems that can guarantee a certain level of requirements satisfaction over time by dynamically composing adaptation strategies when necessary. The proposed framework is illustrated and evaluated through two simulated systems, namely, the Meeting-Scheduling exemplar and an E-Shop.
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