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Pediatric cardiac output measurement using surface integration of velocity vectors : an in vivo validation study

Chew, Michelle (author)
Departments of Anaesthesia and Intensive Care, Institute of Experimental Clinical Research, Skejby Sygehus, Aarhus University Hospital, Denmark
Brandberg, Joakim (author)
Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan
Bjarum, Steinar (author)
Department of Biomerical Engineering, Trondheim University, Norway
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Baek-Jensen, Katrine (author)
Institute of Experimental Clinical Research, Skejby Sygehus, Aarhus University Hospital, Denmark
Sloth, Erik (author)
Departments of Anaesthesia and Intensive Care, Skejby Sygehus, Aarhus University Hospital, Denmark
Ask, Per (author)
Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan
Hasenkam, J. Michael (author)
Department of Cardiothoracic Surgery, Skejby Sygehus, Aarhus University Hospital, Denmark
Janerot Sjöberg, Birgitta (author)
Linköpings universitet,Klinisk fysiologi,Hälsouniversitetet,Hälsouniversitetet, Linköping University
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 (creator_code:org_t)
Ovid Technologies (Wolters Kluwer Health), 2000
2000
English.
In: Critical Care Medicine. - : Ovid Technologies (Wolters Kluwer Health). - 0090-3493 .- 1530-0293. ; 28:11, s. 3664-3671
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Objective: To test the accuracy and reproducibility of systemic cardiac output (CO) measurements using surface integration of velocity vectors (SIVV) in a pediatric animal model with hemodynamic instability and to compare SIVV with traditional pulsed-wave Doppler measurements.Design: Prospective, comparative study.Setting: Animal research laboratory at a university medical center.Subjects: Eight piglets weighing 10-15 kg.Interventions: Hemodynamic instability was induced by using inhalation of isoflurane and infusions of colloid and dobutamine.Measurements: SIVV CO was measured at the left ventricular outflow tract, the aortic valve, and ascending aorta. Transit time CO was used as the reference standard.Results: There was good agreement between SIVV and transit time CO. At high frame rates, the mean difference ± 2 sd between the two methods was 0.01 ± 0.27 L/min for measurements at the left ventricular outflow tract, 0.08 ± 0.26 L/min for the ascending aorta, and 0.06 ± 0.25 L/min for the aortic valve. At low frame rates, measurements were 0.06 ± 0.25, 0.19 ± 0.32, and 0.14 ± 0.30 L/min for the left ventricular outflow tract, ascending aorta, and aortic valve, respectively. There were no differences between the three sites at high frame rates. Agreement between pulsed-wave Doppler and transit time CO was poorer, with a mean difference ± 2 sd of 0.09 ± 0.93 L/min. Repeated SIVV measurements taken at a period of relative hemodynamic stability differed by a mean difference ±2 sd of 0.01 ± 0.22 L/min, with a coefficient of variation = 7.6%. Intraobserver coefficients of variation were 5.7%, 4.9%, and 4.1% at the left ventricular outflow tract, ascending aorta, and aortic valve, respectively. Interobserver variability was also small, with a coefficient of variation = 8.5%.Conclusions: SIVV is an accurate and reproducible flow measurement technique. It is a considerable improvement over currently used methods and is applicable to pediatric critical care.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

Medical engineering
Medicinsk teknik

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