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> Svensson Leif >
Direct or subacute ...
Direct or subacute coronary angiography in out-of-hospital cardiac arrest (DISCO)-An initial pilot-study of a randomized clinical trial
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- Elfwen, Ludvig (författare)
- Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital
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- Lagedal, Rickard (författare)
- Uppsala University,Uppsala universitet,Anestesiologi och intensivvård
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- Nordberg, Per (författare)
- Karolinska Institutet,Karolinska Institute
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- James, Stefan, 1964- (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
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- Oldgren, Jonas, 1964- (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
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- Bohm, Felix (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital
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- Lundgren, Peter (författare)
- Gothenburg University,Göteborgs universitet,University of Borås,University of Gothenburg,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Rylander, Christian, 1960 (författare)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
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- van der Linden, Jan (författare)
- Karolinska Institutet,Karolinska Institute
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- Hollenberg, Jacob (författare)
- Karolinska Institutet,Karolinska Institute
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- Erlinge, David (författare)
- Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups
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- Cronberg, Tobias (författare)
- Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Jensen, Ulf (författare)
- Karolinska Institute,Stockholm South General Hospital
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- Friberg, Hans (författare)
- Lund University,Lunds universitet,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital
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- Lilja, Gisela (författare)
- Lund University,Lunds universitet,Brain Injury After Cardiac Arrest,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Larsson, Ing-Marie, 1963- (författare)
- Uppsala University,Uppsala universitet,Anestesiologi och intensivvård
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- Wallin, Ewa (författare)
- Uppsala University,Uppsala universitet,Anestesiologi och intensivvård
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- Rubertsson, Sten (författare)
- Uppsala University,Uppsala universitet,Anestesiologi och intensivvård
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- Svensson, Leif (författare)
- Karolinska Institutet,Karolinska Institute
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(creator_code:org_t)
- ELSEVIER IRELAND LTD, 2019
- 2019
- Engelska.
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Ingår i: Resuscitation. - : ELSEVIER IRELAND LTD. - 0300-9572 .- 1873-1570. ; 139, s. 253-261
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- Background: The clinical importance of immediate coronary angiography, with potentially subsequent percutaneous coronary intervention (PCI), in out-of-hospital cardiac arrest (OHCA) patients without ST-elevation on the ECG is unclear. In this study, we assessed feasibility and safety aspects of performing immediate coronary angiography in a pre-specified pilot phase of the 'DIrect or Subacute Coronary angiography in Out-of-hospital cardiac arrest' (DISCO) randomized controlled trial (ClinicalTrials.gov ID: NCT02309151). Methods: Resuscitated bystander witnessed OHCA patients > 18 years without ST-elevation on the ECG were randomized to immediate coronary angiography versus standard of care. Event times, procedure related adverse events and safety variables within 7 days were recorded. Results: In total, 79 patients were randomized to immediate angiography (n = 39) or standard of care (n = 40). No major differences in baseline characteristics between the groups were found. There were no differences in the proportion of bleedings and renal failure. Three patients randomized to immediate angiography and six patients randomized to standard care died within 24 h. The median time from EMS arrival to coronary angiography was 135 min in the immediate angiography group. In patients randomized to immediate angiography a culprit lesion was found in 14/38 (36.8%) and PCI was performed in all these patients. In 6/40 (15%) patients randomized to standard of care, coronary angiography was performed before the stipulated 3 days. Conclusion: In this out-of-hospital cardiac arrest population without ST-elevation, randomization to a strategy to perform immediate coronary angiography was feasible although the time window of 120 min from EMS arrival at the scene of the arrest to start of coronary angiography was not achieved. No significant safety issues were reported.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- Out-of-hospital
- Cardiac arrest
- Coronary angiography
- Percutaneous coronary intervention
- Cardiac arrest
- Coronary angiography
- Out-of-hospital
- Percutaneous coronary intervention
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Elfwen, Ludvig
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Lagedal, Rickard
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Nordberg, Per
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James, Stefan, 1 ...
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Oldgren, Jonas, ...
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Bohm, Felix
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visa fler...
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Lundgren, Peter
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Rylander, Christ ...
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van der Linden, ...
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Hollenberg, Jaco ...
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Erlinge, David
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Cronberg, Tobias
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Jensen, Ulf
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Friberg, Hans
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Lilja, Gisela
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Larsson, Ing-Mar ...
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Wallin, Ewa
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Rubertsson, Sten
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Svensson, Leif
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Anestesi och int ...
- Artiklar i publikationen
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Resuscitation
- Av lärosätet
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Uppsala universitet
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Lunds universitet
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Karolinska Institutet
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Göteborgs universitet