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Träfflista för sökning "WFRF:(Brodin Lars Åke) ;pers:(Janerot Sjöberg Birgitta 1958)"

Sökning: WFRF:(Brodin Lars Åke) > Janerot Sjöberg Birgitta 1958

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  • Fraser, AG, et al. (författare)
  • Feasibility and reproducibility of off-line tissue Doppler measurement of regional myocardial function during dobutamine stress echocardiography
  • 2003
  • Ingår i: European Journal of Echocardiography. - 1525-2167 .- 1532-2114. ; 4:1, s. 43-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: Off-line post-processing of colour tissue Doppler from digital loops may allow objective quantification of dobutamine stress echocardiography. We assessed the reproducibility of off-line measurements of regional myocardial velocities. Methods and Results: Nine observers analysed 10 studies, each making 2400 observations. Coefficients of variation in basal segments from apical windows, at rest and maximal stress, were 9-14% and 11-18% for peak systolic velocity, 16-18% and 17-19% for time-to-peak systolic velocity, 9-17% and 18-24% for systolic velocity time integral, and 18-23% and 21-27% for systolic acceleration. Coefficients of variation for diastolic velocities in basal segments at rest were 11-40%. Coefficients of variation for peak systolic velocity were 10-24% at rest and 14-28% at peak in mid segments, and 19-53% and 29-69% in apical segments. From parasternal windows coefficients of variation for peak systolic velocity were 14-16% in basal posterior, and 19-29% in mid-anterior segments. High variability makes measurement unreliable in apical and basal anterior septal segments. The feasibility of obtaining traces was tested in 92 subjects, and >90% in all basal and mid segments apart from the anterior septum. Conclusion: Quantification of myocardial functional reserve by off-line analysis of colour tissue Doppler acquired during dobutamine stress is feasible and reproducible in 11 segments of the left ventricle. The most reliable measurements are systolic velocities of longitudinal motion in basal segments.
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  • Janerot Sjöberg, Birgitta, 1958-, et al. (författare)
  • Mobila tekniker för diagnostik vid sängkanten : Mobile bedside diagnostic techniques
  • 2008
  • Ingår i: Läkartidningen. - 0023-7205 .- 1652-7518. ; 105:43, s. 3025-3030
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Ekokardiografi och mobil myokardskintigrafi är lätta att använda vid sängkanten på akut- och infarktvårdavdelning och kan styra patientflödet.Akut myokardischemi kan påvisas som nedsatt regional väggrörlighet och/eller perfusion med både ekokardiigrafi och ektomografi.Kvantitativ myokardrörlighetsanalys underlättar och minskar subjektiviteten i ischemidiagnostiken.
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  • Ressner, Marcus, 1967-, et al. (författare)
  • Effects of ultrasound contrast agents on Doppler tissue velocity estimation
  • 2006
  • Ingår i: Journal of the American Society of Echocardiography. - : Elsevier BV. - 0894-7317 .- 1097-6795. ; 19:2, s. 154-164
  • Tidskriftsartikel (refereegranskat)abstract
    • The combination of Doppler tissue imaging and myocardial contrast echocardiography has the potential to provide information about motion and perfusion of the myocardium in a single examination. The purpose of this study was to establish how the presence of ultrasound contrast agent (UCA) affects measurements of Doppler tissue velocities in vivo and in vitro. We performed echocardiography in 12 patients with ischemic heart disease before and immediately after a slow intravenous infusion of the UCA Optison, using color Doppler tissue imaging to examine the effect of contrast agents in vivo. The myocardial peak systolic velocities and their integrals were analyzed in digitally stored cineloops before and after contrast administration. To distinguish between methodologic and physiologic factors affecting the measurement of tissue velocity in vitro, experiments with a rotating disk and a flow cone phantom were also carried out for the 3 contrast agents: Optison, Sonovue, and Sonazoid. in vivo results show that the values for peak systolic velocity increased by about 10% during contrast infusion, from mean 5.2 +/- 1.8 to 5.7 +/- 2.3 cm/s (P = .02, 95% confidence interval 2%-16%). The increase in myocardial peak systolic velocities was verified in experimental models in which the UCA increased the estimated mean velocity in the order of 5% to 20% for the motion interval of 5 to 7 cm/s, corresponding to the myocardial velocities studied in vivo. The response was similar for all 3 contrast agents and was not affected by moderate variations in concentration of the agent. We have shown that the presence UCA will affect Doppler tissue measurements in vivo and in vitro. The observed bias is presumed to be an effect of harmonic signal contribution from rupturing contrast agent microbubbles and does not indicate biologic or physiologic effects.
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