SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Brown P) ;lar1:(hh)"

Sökning: WFRF:(Brown P) > Högskolan i Halmstad

  • Resultat 1-3 av 3
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • 2019
  • Tidskriftsartikel (refereegranskat)
  •  
2.
  • Russell, Aaron P., et al. (författare)
  • Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training
  • 2013
  • Ingår i: Journal of Physiology. - Chichester : Wiley-Blackwell. - 0022-3751 .- 1469-7793. ; 591:18, s. 4637-4653
  • Tidskriftsartikel (refereegranskat)abstract
    • The identification of microRNAs (miRNAs) has established new mechanisms that control skeletal muscle adaptation to exercise. The present study investigated the mRNA regulation of components of the miRNA biogenesis pathway (Drosha, Dicer and Exportin-5), muscle enriched miRNAs, (miR-1, -133a, -133b and -206), and several miRNAs dysregulated in muscle myopathies (miR-9, -23, -29, -31 and -181). Measurements were made in muscle biopsies from nine healthy untrained males at rest, 3 h following an acute bout of moderate-intensity endurance cycling and following 10 days of endurance training. Bioinformatics analysis was used to predict potential miRNA targets. In the 3 h period following the acute exercise bout, Drosha, Dicer and Exportin-5, as well as miR-1, -133a, -133-b and -181a were all increased. In contrast miR-9, -23a, -23b and -31 were decreased. Short-term training increased miR-1 and -29b, while miR-31 remained decreased. Negative correlations were observed between miR-9 and HDAC4 protein (r=-0.71; P= 0.04), miR-31 and HDAC4 protein (r =-0.87; P= 0.026) and miR-31 and NRF1 protein (r =-0.77; P= 0.01) 3 h following exercise. miR-31 binding to the HDAC4 and NRF1 3′ untranslated region (UTR) reduced luciferase reporter activity. Exercise rapidly and transiently regulates several miRNA species in muscle. Several of these miRNAs may be involved in the regulation of skeletal muscle regeneration, gene transcription and mitochondrial biogenesis. Identifying endurance exercise-mediated stress signals regulating skeletal muscle miRNAs, as well as validating their targets and regulatory pathways post exercise, will advance our understanding of their potential role/s in human health. © 2013 The Authors. The Journal of Physiology © 2013 The Physiological Society.
  •  
3.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-3 av 3
Typ av publikation
tidskriftsartikel (2)
bokkapitel (1)
Typ av innehåll
refereegranskat (2)
övrigt vetenskapligt/konstnärligt (1)
Författare/redaktör
Kelly, Daniel (1)
Brown, K. (1)
Bengtsson-Palme, Joh ... (1)
Nilsson, Henrik (1)
Kelly, Ryan (1)
Li, Ying (1)
visa fler...
Moore, Matthew D. (1)
Liu, Fang (1)
Zhang, Yao (1)
Jin, Yi (1)
Raza, Ali (1)
Rafiq, Muhammad (1)
Zhang, Kai (1)
Khatlani, T (1)
Kahan, Thomas (1)
Sörelius, Karl, 1981 ... (1)
Batra, Jyotsna (1)
Roobol, Monique J (1)
Backman, Lars (1)
Yan, Hong (1)
Lorkowski, Stefan (1)
Thrift, Amanda G. (1)
Zhang, Wei (1)
Hammerschmidt, Sven (1)
Patil, Chandrashekha ... (1)
Wang, Jun (1)
Pollesello, Piero (1)
Conesa, Ana (1)
El-Esawi, Mohamed A. (1)
Zhang, Weijia (1)
Li, Jian (1)
Marinello, Francesco (1)
Frilander, Mikko J. (1)
Wei, Pan (1)
Badie, Christophe (1)
Zhao, Jing (1)
Li, You (1)
Bansal, Abhisheka (1)
Rahman, Proton (1)
Parchi, Piero (1)
Polz, Martin (1)
Ijzerman, Adriaan P. (1)
Subhash, Santhilal, ... (1)
Quinn, Terence J. (1)
Widén, Kristian (1)
Uversky, Vladimir N. (1)
Gemmill, Alison (1)
Zhang, Yi (1)
Meule, Adrian (1)
Vohl, Marie-Claude (1)
visa färre...
Lärosäte
Högskolan i Halmstad  (3)Ta bort avgränsningen
Lunds universitet (2)
Karolinska Institutet (2)
Göteborgs universitet (1)
Uppsala universitet (1)
Stockholms universitet (1)
visa fler...
Chalmers tekniska högskola (1)
visa färre...
Språk
Engelska (3)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (2)
Naturvetenskap (1)
Teknik (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy