| 1. |
- Björklund, Verna, et al.
(författare)
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Early-onset group B streptococcal infections in five Nordic countries with different prevention policies, 1995 to 2019
- 2024
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Ingår i: Eurosurveillance. - : European Centre for Disease Control and Prevention (ECDC). - 1025-496X .- 1560-7917. ; 29:3
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Tidskriftsartikel (refereegranskat)abstract
- Background: Neonatal early-onset disease caused by group B Streptococcus (GBS) is a leading cause of infant morbidity. Intrapartum antibiotic prophylaxis (IAP) is effective in preventing early-onset GBS disease, but there is no agreement on the optimal strategy for identifying the pregnant women requiring this treatment, and both risk-based prophylaxis (RBP) and GBS screening-based prophylaxis (SBP) are used.Aim: The aim of this study was to evaluate the effect of SBP as a public health intervention on the epidemiology of early-onset GBS infections.Methods: In 2012, Finland started the universal SBP, while Denmark, Iceland, Norway and Sweden continued with RBP. We conducted an interrupted time series analysis taking 2012 as the intervention point to evaluate the impact of this intervention. The incidences of early- and late-onset GBS infections during Period I (1995-2011) and Period II (2012-2019) were collected from each national register, covering 6,605,564 live births.Results: In Finland, a reduction of 58% in the incidence of early-onset GBS disease, corresponding to an incidence rate ratio (IRR) of 0.42 (95% CI: 0.34-0.52), was observed after 2012. At the same time, the pooled IRR of other Nordic countries was 0.89 (95% CI: 0.80-1.0), specifically 0.89 (95% CI: 0.70-1.5) in Denmark, 0.34 (95% CI: 0.15-0.81) in Iceland, 0.72 (95% CI: 0.59-0.88) in Norway and 0.97 (95% CI: 0.85-1.1) in Sweden.Conclusions: In this ecological study of five Nordic countries, early-onset GBS infections were approximately halved following introduction of the SBP approach as compared with RBP.
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| 2. |
- Nilsson, Annika E., et al.
(författare)
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Towards extended shared socioeconomic pathways : A combined participatory bottom-up and top-down methodology with results from the Barents region
- 2017
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Ingår i: Global Environmental Change. - : ELSEVIER SCI LTD. - 0959-3780 .- 1872-9495. ; 45, s. 124-132
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Tidskriftsartikel (refereegranskat)abstract
- A major challenge in planning for adaptation to climate change is to assess future development not only in relation to climate but also in relation to social, economic and political changes that affect the capacity for adaptation or otherwise play a role in decision making. One approach is to use scenario methods. This article presents a methodology that combines top-down scenarios and bottom-up approaches to scenario building, with the aim of articulating local so-called extended socio-economic pathways. Specifically, we used the Shared Socioeconomic Pathways (SSPs) of the global scenario framework as developed by the climate research community to present boundary conditions about potential global change in workshop discussion with local and regional actors in the Barents region. We relate the results from these workshops to the different elements of the global SSPs and discuss potential and limitations of the method in relation to use in decision making processes.
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| 3. |
- Nilsson, Annika E., et al.
(författare)
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Uncertain futures : the changing global context of the European Arctic. Report from a scenario workshop in Pajala, Sweden
- 2015
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- What does the future look like from the perspective of a small municipality in northern Sweden? What social and environmental challenges might there be and how might local people respond? This report presents findings from a workshop in which actors from Pajala municipality and the surrounding region in northern Sweden discussed, together with researchers, challenges for long-term planning posed by a rapidly changing and uncertain global context. The workshop piloted a new approach combining bottom-up participation with scenario work generated within the international climate change research community, in order to construct locally and regionally relevant narratives of possible futures. The resulting narratives feature some issues that do not figure prominently in the assessment of global futures, but also show that local development is perceived as closely linked to global processes, such as changes related to climate and demography. The report’s purpose is to document the workshop results and offer a description of and reflection on the methods employed as a basis for further development of the approach.
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| 4. |
- Olstrup, Henrik, et al.
(författare)
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The Long-Term Mortality Effects Associated with Exposure to Particles and NOx in the Malmö Diet and Cancer Cohort
- 2023
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Ingår i: Toxics. - : MDPI. - 2305-6304. ; 11:11
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Tidskriftsartikel (refereegranskat)abstract
- In this study, the long-term mortality effects associated with exposure to PM10 (particles with an aerodynamic diameter smaller than or equal to 10 µm), PM2.5 (particles with an aerodynamic diameter smaller than or equal to 2.5 µm), BC (black carbon), and NOx (nitrogen oxides) were analyzed in a cohort in southern Sweden during the period from 1991 to 2016. Participants (those residing in Malmö, Sweden, born between 1923 and 1950) were randomly recruited from 1991 to 1996. At enrollment, 30,438 participants underwent a health screening, which consisted of questionnaires about lifestyle and diet, a clinical examination, and blood sampling. Mortality data were retrieved from the Swedish National Cause of Death Register. The modeled concentrations of PM10, PM2.5, BC, and NOx at the cohort participants’ home addresses were used to assess air pollution exposure. Cox proportional hazard models were used to estimate the associations between long-term exposure to PM10, PM2.5, BC, and NOx and the time until death among the participants during the period from 1991 to 2016. The hazard ratios (HRs) associated with an interquartile range (IQR) increase in each air pollutant were calculated based on the exposure lag windows of the same year (lag0), 1–5 years (lag1–5), and 6–10 years (lag6–10). Three models were used with varying adjustments for possible confounders including both single-pollutant estimates and two-pollutant estimates. With adjustments for all covariates, the HRs for PM10, PM2.5, BC, and NOx in the single-pollutant models at lag1–5 were 1.06 (95% CI: 1.02–1.11), 1.01 (95% CI: 0.95–1.08), 1.07 (95% CI: 1.04–1.11), and 1.11 (95% CI: 1.07–1.16) per IQR increase, respectively. The HRs, in most cases, decreased with the inclusion of a larger number of covariates in the models. The most robust associations were shown for NOx, with statistically significant positive HRs in all the models. An overall conclusion is that road traffic-related pollutants had a significant association with mortality in the cohort.
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