↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Cherney Samantha) "

Search: WFRF:(Cherney Samantha)

Result 1-1 of 1

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Frazier-Wood, Alexis C., et al. (author) Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses 2016 In: Nature Genetics. - : Nature Research (part of Springer Nature). - 1061-4036 .- 1546-1718. ; 48, s. 624- Journal article (peer-reviewed)abstract Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with both of these traits, has not yet been studied with genome-wide data. We conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n = 161,460), and neuroticism (n = 170,911). We identify 3 variants associated with subjective well-being, 2 variants associated with depressive symptoms, and 11 variants associated with neuroticism, including 2 inversion polymorphisms. The two loci associated with depressive symptoms replicate in an independent depression sample. Joint analyses that exploit the high genetic correlations between the phenotypes (vertical bar(p) over cap vertical bar approximate to 0.8) strengthen the overall credibility of the findings and allow us to identify additional variants. Across our phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-1 of 1

Refine your search

Type of publication: journal article (1)

Type of content: peer-reviewed (1)

Author/Editor: Johannesson, Magnus (1); Davey Smith, George (1); Rudan, Igor (1); Kraft, Peter (1); Ahluwalia, Tarunveer ... (1); Koellinger, Philipp ... (1); show more...; Nolte, IM (1); Hansen, Torben (1); Snieder, H. (1); Amin, Najaf (1); Magnusson, Patrik K ... (1); Pedersen, Nancy L (1); Zhao, Wei (1); Lehtimäki, Terho (1); Lee, James J. (1); Thorleifsson, Gudmar (1); Thorsteinsdottir, Un ... (1); Stefansson, Kari (1); Gieger, Christian (1); Boomsma, Dorret I. (1); Spector, Tim D. (1); Kaprio, Jaakko (1); Karlsson, Robert (1); Alizadeh, Behrooz Z (1); Realo, Anu (1); Metspalu, Andres (1); Forstner, Andreas J (1); Eriksson, Johan G. (1); Schmidt, Reinhold (1); Schmidt, Helena (1); Deary, Ian J (1); Cucca, Francesco (1); Sørensen, Thorkild I ... (1); Montgomery, Grant W. (1); Cesarini, David (1); Jöckel, Karl-Heinz (1); Smith, Albert Vernon (1); Harris, Tamara B (1); Launer, Lenore J (1); Hofman, Albert (1); Kolcic, Ivana (1); Rich, Stephen S (1); Starr, John M (1); Uitterlinden, André ... (1); Hayward, Caroline (1); Järvelin, Marjo-Riit ... (1); Gudnason, Vilmundur (1); Polasek, Ozren (1); Rawal, Rajesh (1); Kumari, Meena (1); show less...

University: Stockholm School of Economics (1); Karolinska Institutet (1)

Language: English (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

Year: 2016 (1)

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view