Sökning: WFRF:(Christakou Athanasia E.)
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Solid tumor spheroi...
Solid tumor spheroid formation by temperature-controlled high voltage ultrasound in a multi-well microdevice
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- Christakou, Athanasia E. (författare)
- KTH,Cellens fysik
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- Ohlin, Mathias (författare)
- KTH,Tillämpad fysik
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- Önfelt, Björn (författare)
- KTH,Cellens fysik
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visa fler...
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- Wiklund, Martin (författare)
- KTH,Biomedicinsk fysik och röntgenfysik
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visa färre...
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(creator_code:org_t)
- Chemical and Biological Microsystems SocietyChemical and Biological Microsystems Society, 2014
- 2014
- Engelska.
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Ingår i: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. - : Chemical and Biological Microsystems SocietyChemical and Biological Microsystems Society. - 9780979806476 ; , s. 573-575
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- In the present work we demonstrate effective 3D growth of human hepatocellular carcinoma (HCC) HepG2 cell spheroids in parallel in a multi-well microdevice actuated with high voltage ultrasound in a temperature-controlled system. We compare the spheroid formation during continuous ultrasound exposure for one week where we formed spheroids in 59% of the wells, with the spheroid formation without ultrasound actuation, where we obtained 0% spheroids. Furthermore, we present an application of the tumor spheroids for investigating natural killer (NK) cells behavior against solid tumors.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Nyckelord
- Microchip
- Multi-well
- Natural killer cells
- Solid tumor
- Spheroid
- Ultrasound
- Temperature control
- Tumors
- Multi wells
- Solid tumors
- Ultrasonics
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)
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