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Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe

Frantz, Laurent A. F. (author)
Haile, James (author)
Lin, Audrey T. (author)
show more...
Scheu, Amelie (author)
Geörg, Christina (author)
Benecke, Norbert (author)
Alexander, Michelle (author)
Linderholm, Anna (author)
Mullin, Victoria E. (author)
Daly, Kevin G. (author)
Battista, Vincent M. (author)
Price, Max (author)
Gron, Kurt J. (author)
Alexandri, Panoraia (author)
Arbogast, Rose-Marie (author)
Arbuckle, Benjamin (author)
Bӑlӑşescu, Adrian (author)
Barnett, Ross (author)
Bartosiewicz, László (author)
Stockholms universitet,Institutionen för arkeologi och antikens kultur
Baryshnikov, Gennady (author)
Bonsall, Clive (author)
Borić, Dušan (author)
Boroneanţ, Adina (author)
Bulatović, Jelena (author)
Çakirlar, Canan (author)
Carretero, José-Miguel (author)
Chapman, John (author)
Church, Mike (author)
Crooijmans, Richard (author)
De Cupere, Bea (author)
Detry, Cleia (author)
Dimitrijevic, Vesna (author)
Dumitraşcu, Valentin (author)
du Plessis, Louis (author)
Edwards, Ceiridwen J. (author)
Erek, Cevdet Merih (author)
Erim-Özdoğan, Aslı (author)
Ervynck, Anton (author)
Fulgione, Domenico (author)
Gligor, Mihai (author)
Götherström, Anders (author)
Stockholms universitet,Institutionen för arkeologi och antikens kultur
Gourichon, Lionel (author)
Groenen, Martien A. M. (author)
Helmer, Daniel (author)
Hongo, Hitomi (author)
Horwitz, Liora K. (author)
Irving-Pease, Evan K. (author)
Lebrasseur, Ophélie (author)
Lesur, Joséphine (author)
Malone, Caroline (author)
Manaseryan, Ninna (author)
Marciniak, Arkadiusz (author)
Martlew, Holley (author)
Mashkour, Marjan (author)
Matthews, Roger (author)
Matuzeviciute, Giedre Motuzaite (author)
Maziar, Sepideh (author)
Meijaard, Erik (author)
McGovern, Tom (author)
Megens, Hendrik-Jan (author)
Miller, Rebecca (author)
Mohaseb, Azadeh Fatemeh (author)
Orschiedt, Jörg (author)
Orton, David (author)
Papathanasiou, Anastasia (author)
Pearson, Mike Parker (author)
Pinhasi, Ron (author)
Radmanović, Darko (author)
Ricaut, François-Xavier (author)
Richards, Mike (author)
Sabin, Richard (author)
Sarti, Lucia (author)
Schier, Wolfram (author)
Sheikhi, Shiva (author)
Stephan, Elisabeth (author)
Stewart, John R. (author)
Stoddart, Simon (author)
Tagliacozzo, Antonio (author)
Tasić, Nenad (author)
Trantalidou, Katerina (author)
Tresset, Anne (author)
Valdiosera, Cristina (author)
van den Hurk, Youri (author)
Van Poucke, Sophie (author)
Vigne, Jean-Denis (author)
Yanevich, Alexander (author)
Zeeb-Lanz, Andrea (author)
Triantafyllidis, Alexandros (author)
Gilbert, M. Thomas P. (author)
Schibler, Jörg (author)
Rowley-Conwy, Peter (author)
Zeder, Melinda (author)
Peters, Joris (author)
Cucchi, Thomas (author)
Bradley, Daniel G. (author)
Dobney, Keith (author)
Burger, Joachim (author)
Evin, Allowen (author)
Girdland-Flink, Linus (author)
Larson, Greger (author)
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 (creator_code:org_t)
2019-08-12
2019
English.
In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 116:35, s. 17231-17238
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Archaeological evidence indicates that pig domestication had begun by similar to 10,500 y before the present ( BP) in the Near East, and mitochondrial DNA ( mtDNA) suggests that pigs arrived in Europe alongside farmers similar to 8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local European wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hypotheses, we obtained mtDNA sequences from 2,099 modern and ancient pig samples and 63 nuclear ancient genomes from Near Eastern and European pigs. Our analyses revealed that European domestic pigs dating from 7,100 to 6,000 y BP possessed both Near Eastern and European nuclear ancestry, while later pigs possessed no more than 4% Near Eastern ancestry, indicating that gene flow from European wild boars resulted in a near-complete disappearance of Near East ancestry. In addition, we demonstrate that a variant at a locus encoding black coat color likely originated in the Near East and persisted in European pigs. Altogether, our results indicate that while pigs were not independently domesticated in Europe, the vast majority of human-mediated selection over the past 5,000 y focused on the genomic fraction derived from the European wild boars, and not on the fraction that was selected by early Neolithic farmers over the first 2,500 y of the domestication process.

Subject headings

NATURVETENSKAP  -- Biologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences (hsv//eng)

Keyword

domestication
evolution
gene flow
Neolithic

Publication and Content Type

ref (subject category)
art (subject category)

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By the author/editor
Frantz, Laurent ...
Haile, James
Lin, Audrey T.
Scheu, Amelie
Geörg, Christina
Benecke, Norbert
show more...
Alexander, Miche ...
Linderholm, Anna
Mullin, Victoria ...
Daly, Kevin G.
Battista, Vincen ...
Price, Max
Gron, Kurt J.
Alexandri, Panor ...
Arbogast, Rose-M ...
Arbuckle, Benjam ...
Bӑlӑşescu, Adria ...
Barnett, Ross
Bartosiewicz, Lá ...
Baryshnikov, Gen ...
Bonsall, Clive
Borić, Dušan
Boroneanţ, Adina
Bulatović, Jelen ...
Çakirlar, Canan
Carretero, José- ...
Chapman, John
Church, Mike
Crooijmans, Rich ...
De Cupere, Bea
Detry, Cleia
Dimitrijevic, Ve ...
Dumitraşcu, Vale ...
du Plessis, Loui ...
Edwards, Ceiridw ...
Erek, Cevdet Mer ...
Erim-Özdoğan, As ...
Ervynck, Anton
Fulgione, Domeni ...
Gligor, Mihai
Götherström, And ...
Gourichon, Lione ...
Groenen, Martien ...
Helmer, Daniel
Hongo, Hitomi
Horwitz, Liora K ...
Irving-Pease, Ev ...
Lebrasseur, Ophé ...
Lesur, Joséphine
Malone, Caroline
Manaseryan, Ninn ...
Marciniak, Arkad ...
Martlew, Holley
Mashkour, Marjan
Matthews, Roger
Matuzeviciute, G ...
Maziar, Sepideh
Meijaard, Erik
McGovern, Tom
Megens, Hendrik- ...
Miller, Rebecca
Mohaseb, Azadeh ...
Orschiedt, Jörg
Orton, David
Papathanasiou, A ...
Pearson, Mike Pa ...
Pinhasi, Ron
Radmanović, Dark ...
Ricaut, François ...
Richards, Mike
Sabin, Richard
Sarti, Lucia
Schier, Wolfram
Sheikhi, Shiva
Stephan, Elisabe ...
Stewart, John R.
Stoddart, Simon
Tagliacozzo, Ant ...
Tasić, Nenad
Trantalidou, Kat ...
Tresset, Anne
Valdiosera, Cris ...
van den Hurk, Yo ...
Van Poucke, Soph ...
Vigne, Jean-Deni ...
Yanevich, Alexan ...
Zeeb-Lanz, Andre ...
Triantafyllidis, ...
Gilbert, M. Thom ...
Schibler, Jörg
Rowley-Conwy, Pe ...
Zeder, Melinda
Peters, Joris
Cucchi, Thomas
Bradley, Daniel ...
Dobney, Keith
Burger, Joachim
Evin, Allowen
Girdland-Flink, ...
Larson, Greger
show less...
About the subject
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
Articles in the publication
Proceedings of t ...
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Stockholm University

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