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Unmet Needs in High...
Unmet Needs in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms (WHO G3)
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- Sorbye, Halfdan (author)
- Haukeland Hosp, Dept Oncol & Clin Sci, Bergen, Norway
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- Baudin, Eric (author)
- Gustave Roussy, Endocrine Oncol, Villejuif, France
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- Borbath, Ivan (author)
- Clin Univ St Luc, Hepato Gastroenterol Unit, Brussels, Belgium
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- Caplin, Martyn (author)
- Royal Free Hosp, Neuroendocrine Tumour Unit, Ctr Gastroenterol, London, England
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- Chen, Jie (author)
- Sun Yat Sen Univ, Dept Gastroenterol, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China
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- Cwikla, Jaroslaw B (author)
- Univ Warmia & Mazury, Fac Med Sci, Olsztyn, Poland
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- Frilling, Andrea (author)
- Imperial Coll London, Dept Surg & Canc, London, England
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- Grossman, Ashley (author)
- Royal Free Hosp, Neuroendocrine Tumour Unit, London, England
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- Kaltsas, Gregory (author)
- Univ Athens, Athens, Greece
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- Scarpa, Aldo (author)
- Univ & Hosp Trust Verona, ARC Net Ctr Appl Res Canc, Verona, Italy; Univ & Hosp Trust Verona, Dept Diagnost & Publ Hlth, Sect Pathol, Verona, Italy
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- Welin, Staffan (author)
- Uppsala universitet,Onkologisk endokrinologi
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- Garcia-Carbonero, Rocio (author)
- Univ Complutense Madrid, Hosp Univ 12 Octubre, Oncol Dept, CIBERONC,CNIO, Madrid, Spain
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- Falkerby, Jenny (contributor)
- Uppsala universitet,Onkologisk endokrinologi
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- Sundin, Anders, 1954- (contributor)
- Uppsala universitet,Radiologi
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- Tiensuu Janson, Eva (contributor)
- Uppsala universitet,Onkologisk endokrinologi
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- Welin, Staffan (contributor)
- Uppsala universitet,Onkologisk endokrinologi
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(creator_code:org_t)
- 2018-08-28
- 2019
- English.
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In: Neuroendocrinology. - : S. Karger AG. - 0028-3835 .- 1423-0194. ; 108:1, s. 54-62
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Abstract
Subject headings
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- Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are classified based on morphology and graded based on their proliferation rate as either well-differentiated low-grade (G1 to G2) neuroendocrine tumors (NET) or poorly differentiated high-grade (G3) neuroendocrine carcinomas (NEC). Recently, a new subgroup of well-differentiated high-grade pancreatic tumors (NET G3) has been defined. The GEP NEN G3 group consisting of both NEC and NET G3 has recently been shown to be a quite heterogeneous patient group concerning prognosis and treatment benefit, depending on factors such as the primary tumor site, differentiation, proliferation rate, and molecular alterations. In this review we discuss the existing data on diagnostics, treatment, and biomarkers in this patient group, the unmet needs, and the future perspectives.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Neuroendocrine carcinoma
- Neuroendocrine neoplasm
- Neuroendocrine tumor
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Sorbye, Halfdan
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Baudin, Eric
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Borbath, Ivan
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Caplin, Martyn
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Chen, Jie
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Cwikla, Jaroslaw ...
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Frilling, Andrea
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Grossman, Ashley
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Kaltsas, Gregory
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Scarpa, Aldo
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Welin, Staffan
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Garcia-Carbonero ...
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Falkerby, Jenny
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Sundin, Anders, ...
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Tiensuu Janson, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Neurosciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
- Articles in the publication
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Neuroendocrinolo ...
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Uppsala University